Q96FZ2: Abasic site processing protein HMCES {ECO:0000305}

General Information

Protein names	- Abasic site processing protein HMCES {ECO:0000305} - Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000312\|HGNC:HGNC:24446} - ES cell-specific 5hmC-binding protein {ECO:0000312\|HGNC:HGNC:24446} - Peptidase HMCES {ECO:0000305} - 3.4.-.- {ECO:0000250\|UniProtKB:Q8R1M0} - Putative endonuclease HMCES {ECO:0000305} - 3.1.25.- {ECO:0000250\|UniProtKB:Q8R1M0} - SRAP domain-containing protein 1
Gene names	HMCES
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96FZ2

1 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MCGRTSCHLP RDVLTRACAY QDRRGQQRLP EWRDPDKYCP SYNKSPQSNS PVLLSRLHFE
        70         80         90        100        110        120
KDADSSERII APMRWGLVPS WFKESDPSKL QFNTTNCRSD TVMEKRSFKV PLGKGRRCVV
       130        140        150        160        170        180
LADGFYEWQR CQGTNQRQPY FIYFPQIKTE KSGSIGAADS PENWEKVWDN WRLLTMAGIF
       190        200        210        220        230        240
DCWEPPEGGD VLYSYTIITV DSCKGLSDIH HRMPAILDGE EAVSKWLDFG EVSTQEALKL
       250        260        270        280        290        300
IHPTENITFH AVSSVVNNSR NNTPECLAPV DLVVKKELRA SGSSQRMLQW LATKSPKKED
       310        320        330        340        350
SKTPQKEESD VPQWSSQFLQ KSPLPTKRGT AGLLEQWLKR EKEEEPVAKR PYSQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

1 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96FZ2-1-unknown	MCGRTS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...WLDFGE	230	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000421895
...FGEVST	233	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000424594
...PVDLVV	273	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000426276
...TKRGTA	330	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000423132
...RPYSQ	354	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...RPYSQ	354		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)