Q96G74: OTU domain-containing protein 5

General Information

Protein names	- OTU domain-containing protein 5 - 3.4.19.12 - Deubiquitinating enzyme A - DUBA
Gene names	OTUD5
Organism	Homo sapiens
Protease Family
Protease ID	C85.001
Chromosome location
UniProt ID	Q96G74

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of OTU domain-containing protein 5 - Isoform 3 of OTU domain-containing protein 5 - Isoform 4 of OTU domain-containing protein 5 - Isoform 5 of OTU domain-containing protein 5

Sequence View

        10         20         30         40         50         60
MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR
        70         80         90        100        110        120
PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA
       130        140        150        160        170        180
AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE
       190        200        210        220        230        240
YEAAAARIEA MDPATVEQQE HWFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH
       250        260        270        280        290        300
EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ
       310        320        330        340        350        360
YSTGTSAVEP INTFHGIHQN EDEPIRVSYH RNIHYNSVVN PNKATIGVGL GLPSFKPGFA
       370        380        390        400        410        420
EQSLMKNAIK TSEESWIEQQ MLEDKKRATD WEATNEAIEE QVARESYLQW LRDQEKQARQ
       430        440        450        460        470        480
VRGPSQPRKA SATCSSATAA ASSGLEEWTS RSPRQRSSAS SPEHPELHAE LGMKPPSPGT
       490        500        510        520        530        540
VLALAKPPSP CAPGTSSQFS AGADRATSPL VSLYPALECR ALIQQMSPSA FGLNDWDDDE
       550        560        570
ILASVLAVSQ QEYLDSMKKN KVHRDPPPDK S         10         20         30         40         50         60
MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR
        70         80         90        100        110        120
PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA
       130        140        150        160        170        180
AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE
       190        200        210        220        230        240
YEAAAARIEA MDPATVEQQE HWFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH
       250        260        270        280        290        300
EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ
       310        320        330        340        350        360
YSTGTSAVEP INTFHGIHQN EDEPIRVSYH RNIHYNSVVN PNKATIGVGL GLPSFKPGFA
       370        380        390        400        410        420
EQSLMKNAIK TSEESWIEQQ MLEDKKRATD WEATNEAIEE QVARESYLQW LRDQEKQARQ
       430        440        450        460        470        480
VRGPSQPRKA SATCSSATAA ASSGLEEWTS RSPRQRSSAS SPEHPELHAE LGMKPPSPGT
       490        500        510        520        530        540
VLALAKPPSP CAPGTSSQFS AGADRATSPL VSLYPALECR ALIQQMSPSA FGLNDWDDDE
       550        560        570
ILASVLAVSQ QEYLDSMKKN KVHRDPPPDK S         10         20         30         40         50         60
MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR
        70         80         90        100        110        120
PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA
       130        140        150        160        170        180
AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE
       190        200        210        220        230        240
YEAAAARIEA MDPATVEQQE HWFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH
       250        260        270        280        290        300
EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ
       310        320        330        340        350        360
YSTGTSAVEP INTFHGIHQN EDEPIRVSYH RNIHYNSVVN PNKATIGVGL GLPSFKPGFA
       370        380        390        400        410        420
EQSLMKNAIK TSEESWIEQQ MLEDKKRATD WEATNEAIEE QVARESYLQW LRDQEKQARQ
       430        440        450        460        470        480
VRGPSQPRKA SATCSSATAA ASSGLEEWTS RSPRQRSSAS SPEHPELHAE LGMKPPSPGT
       490        500        510        520        530        540
VLALAKPPSP CAPGTSSQFS AGADRATSPL VSLYPALECR ALIQQMSPSA FGLNDWDDDE
       550        560        570
ILASVLAVSQ QEYLDSMKKN KVHRDPPPDK S         10         20         30         40         50         60
MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR
        70         80         90        100        110        120
PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA
       130        140        150        160        170        180
AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE
       190        200        210        220        230        240
YEAAAARIEA MDPATVEQQE HWFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH
       250        260        270        280        290        300
EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ
       310        320        330        340        350        360
YSTGTSAVEP INTFHGIHQN EDEPIRVSYH RNIHYNSVVN PNKATIGVGL GLPSFKPGFA
       370        380        390        400        410        420
EQSLMKNAIK TSEESWIEQQ MLEDKKRATD WEATNEAIEE QVARESYLQW LRDQEKQARQ
       430        440        450        460        470        480
VRGPSQPRKA SATCSSATAA ASSGLEEWTS RSPRQRSSAS SPEHPELHAE LGMKPPSPGT
       490        500        510        520        530        540
VLALAKPPSP CAPGTSSQFS AGADRATSPL VSLYPALECR ALIQQMSPSA FGLNDWDDDE
       550        560        570
ILASVLAVSQ QEYLDSMKKN KVHRDPPPDK S

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96G74-1-unknown	MTILPK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96G74-1-unknown	MTILPK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83923
Q96G74-1-unknown	MTILPK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83925
Q96G74-128-unknown	GVVVGV...	128	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390767
Q96G74-128-unknown	GVVVGV...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197394
Q96G74-128-unknown	GVVVGV...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197392
Q96G74-128-unknown	GVVVGV...	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197393
Q96G74-218-unknown	MKEDGA...	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt83924
Q96G74-218-unknown	MKEDGA...	218	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401629
Q96G74-218-unknown	MKEDGA...	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107768
Q96G74-218-unknown	MKEDGA...	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107766
Q96G74-218-unknown	MKEDGA...	218	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107767

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PPDKS	571	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PPDKS	571	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79542
...PPDKS	571	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79540
...PPDKS	571	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79543

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)