Q96GD4: Aurora kinase B

General Information

Protein names	- Aurora kinase B - 2.7.11.1 - Aurora 1 - Aurora- and IPL1-like midbody-associated protein 1 - AIM-1 - Aurora/IPL1-related kinase 2 - ARK-2 - Aurora-related kinase 2 - STK-1 - Serine/threonine-protein kinase 12 - Serine/threonine-protein kinase 5 - Serine/threonine-protein kinase aurora-B
Gene names	AURKB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96GD4

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Aurora kinase B - Isoform 3 of Aurora kinase B - Isoform 4 of Aurora kinase B - Isoform 5 of Aurora kinase B

Sequence View

        10         20         30         40         50         60
MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN
        70         80         90        100        110        120
SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH
       130        140        150        160        170        180
QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI
       190        200        210        220        230        240
MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL
       250        260        270        280        290        300
PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPMGA
       310        320        330        340
QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA         10         20         30         40         50         60
MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN
        70         80         90        100        110        120
SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH
       130        140        150        160        170        180
QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI
       190        200        210        220        230        240
MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL
       250        260        270        280        290        300
PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPMGA
       310        320        330        340
QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA         10         20         30         40         50         60
MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN
        70         80         90        100        110        120
SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH
       130        140        150        160        170        180
QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI
       190        200        210        220        230        240
MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL
       250        260        270        280        290        300
PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPMGA
       310        320        330        340
QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA         10         20         30         40         50         60
MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN
        70         80         90        100        110        120
SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH
       130        140        150        160        170        180
QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI
       190        200        210        220        230        240
MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL
       250        260        270        280        290        300
PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPMGA
       310        320        330        340
QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96GD4-1-unknown	MAQKEN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96GD4-1-unknown	MAQKEN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68024
Q96GD4-1-unknown	MAQKEN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68025
Q96GD4-1-unknown	MAQKEN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68027
Q96GD4-42-unknown	MSRSNV...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt68026
Q96GD4-42-unknown	MSRSNV...	42	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000443869
Q96GD4-42-unknown	MSRSNV...	42	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463636
Q96GD4-42-unknown	MSRSNV...	42	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464031
Q96GD4-42-unknown	MSRSNV...	42	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462027
Q96GD4-42-unknown	MSRSNV...	42	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q96GD4-42-unknown	MSRSNV...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106257
Q96GD4-42-unknown	MSRSNV...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106258
Q96GD4-42-unknown	MSRSNV...	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106259

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVLFKS	110	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462027
...KVLFKS	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113532
...KVLFKS	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113531
...KVLFKS	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113533
...GLKGEL	213	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464031
...GLKGEL	213	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113528
...GLKGEL	213	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113527
...GLKGEL	213	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113529
...HAPSLR	228	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462930
...HAPSLR	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113524
...HAPSLR	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113523
...HAPSLR	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113525
...LLVGNP	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463636
...LLVGNP	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113520
...LLVGNP	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113519
...LLVGNP	270	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113521
...LQSVA	344	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LQSVA	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63644
...LQSVA	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63642
...LQSVA	344	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt63645

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)