Q96HH9: GRAM domain-containing protein 2B

General Information

Protein names	- GRAM domain-containing protein 2B - HCV NS3-transactivated protein 2
Gene names	GRAMD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96HH9

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD

Isoforms

- Isoform 2 of GRAM domain-containing protein 3 - Isoform 3 of GRAM domain-containing protein 3 - Isoform 4 of GRAM domain-containing protein 3 - Isoform 5 of GRAM domain-containing protein 3 - Isoform 2 of GRAM domain-containing protein 2B - Isoform 3 of GRAM domain-containing protein 2B - Isoform 4 of GRAM domain-containing protein 2B - Isoform 5 of GRAM domain-containing protein 2B

Sequence View

        10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD         10         20         30         40         50         60
MTELQQDVED TKPAKVLGKR ESKLGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
        70         80         90        100        110        120
QKKIISLWSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSSQYKANM HFHKLFLSVP
       130        140        150        160        170        180
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
       190        200        210        220        230        240
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
       250        260        270        280        290        300
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHATESQ TVLNVSKGEA
       310        320        330        340        350        360
KPTRADAHVN RVPEGKAKSL PVQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
       370        380        390        400        410        420
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLRSQVQ FNVEVLCQEL TANIVKLEKI
       430
QNNLQKLLEN GD

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96HH9-1-Acetylation	MTELQQ...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96HH9-2-unknown	TELQQD...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LENGD	432	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LENGD	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72008
...LENGD	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72007
...LENGD	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72005
...LENGD	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72006

TopFIND

Q96HH9: GRAM domain-containing protein 2B

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates