Q96KR7: Phosphatase and actin regulator 3

General Information

Protein names	- Phosphatase and actin regulator 3 - Scaffold-associated PP1-inhibiting protein - Scapinin
Gene names	PHACTR3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96KR7

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Phosphatase and actin regulator 3 - Isoform 3 of Phosphatase and actin regulator 3 - Isoform 4 of Phosphatase and actin regulator 3

Sequence View

        10         20         30         40         50         60
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP EYLVSGIRTP
        70         80         90        100        110        120
PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA GRQGREELIK KGLLEMMEQD
       130        140        150        160        170        180
AESKTCNPDG GPRSVQSEPP TPKSETLTSE DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA
       190        200        210        220        230        240
AKMPSASSGE EADAGSLLPT TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK
       250        260        270        280        290        300
ASSKTTKNVT GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA
       310        320        330        340        350        360
LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE NKRTAAKESE
       370        380        390        400        410        420
ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK ELLAVKLRNR PSKQELEDRN
       430        440        450        460        470        480
IFPRRTDEER QEIRQQIEMK LSKRLSQRPA VEELERRNIL KQRNDQTEQE ERREIKQRLT
       490        500        510        520        530        540
RKLNQRPTVD ELRDRKILIR FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK
       550
SNEMEVHASS KHLTRFHRP         10         20         30         40         50         60
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP EYLVSGIRTP
        70         80         90        100        110        120
PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA GRQGREELIK KGLLEMMEQD
       130        140        150        160        170        180
AESKTCNPDG GPRSVQSEPP TPKSETLTSE DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA
       190        200        210        220        230        240
AKMPSASSGE EADAGSLLPT TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK
       250        260        270        280        290        300
ASSKTTKNVT GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA
       310        320        330        340        350        360
LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE NKRTAAKESE
       370        380        390        400        410        420
ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK ELLAVKLRNR PSKQELEDRN
       430        440        450        460        470        480
IFPRRTDEER QEIRQQIEMK LSKRLSQRPA VEELERRNIL KQRNDQTEQE ERREIKQRLT
       490        500        510        520        530        540
RKLNQRPTVD ELRDRKILIR FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK
       550
SNEMEVHASS KHLTRFHRP         10         20         30         40         50         60
MAASEDGSGC LVSRGRSQSD PSVLTDSSAT SSADAGENPD EMDQTPPARP EYLVSGIRTP
        70         80         90        100        110        120
PVRRNSKLAT LGRIFKPWKW RKKKNEKLKQ TTSALEKKMA GRQGREELIK KGLLEMMEQD
       130        140        150        160        170        180
AESKTCNPDG GPRSVQSEPP TPKSETLTSE DAQPGSPLAT GTDQVSLDKP LSSAAHLDDA
       190        200        210        220        230        240
AKMPSASSGE EADAGSLLPT TNELSQALAG ADSLDSPPRP LERSVGQLPS PPLLPTPPPK
       250        260        270        280        290        300
ASSKTTKNVT GQATLFQASS MKSADPSLRG QLSTPTGSPH LTTVHRPLPP SRVIEELHRA
       310        320        330        340        350        360
LATKHRQDSF QGRESKGSPK KRLDVRLSRT SSVERGKERE EAWSFDGALE NKRTAAKESE
       370        380        390        400        410        420
ENKENLIINS ELKDDLLLYQ DEEALNDSII SGTLPRKCKK ELLAVKLRNR PSKQELEDRN
       430        440        450        460        470        480
IFPRRTDEER QEIRQQIEMK LSKRLSQRPA VEELERRNIL KQRNDQTEQE ERREIKQRLT
       490        500        510        520        530        540
RKLNQRPTVD ELRDRKILIR FSDYVEVAKA QDYDRRADKP WTRLSAADKA AIRKELNEYK
       550
SNEMEVHASS KHLTRFHRP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96KR7-1-unknown	MAASED...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96KR7-42-unknown	MDQTPP...	42	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85011
Q96KR7-42-unknown	MDQTPP...	42	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85012
Q96KR7-42-unknown	MDQTPP...	42	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96989
Q96KR7-112-	GLLEMM...	112		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
Q96KR7-112-unknown	GLLEMM...	112	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177495
Q96KR7-112-unknown	GLLEMM...	112	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177496
Q96KR7-112-unknown	GLLEMM...	112	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177494

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RFHRP	559	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RFHRP	559	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80630
...RFHRP	559	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80629
...RFHRP	559	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80631

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)