Q96KS0: Egl nine homolog 2 {ECO:0000305}

General Information

Protein names	- Egl nine homolog 2 {ECO:0000305} - 1.14.11.29 {ECO:0000255\|PROSITE-ProRule:PRU00805, ECO:0000269\|PubMed:11595184, ECO:0000269\|PubMed:12039559, ECO:0000269\|PubMed:15925519} - Estrogen-induced tag 6 {ECO:0000303\|PubMed:11850811} - EIT-6 {ECO:0000303\|PubMed:11850811} - HPH-3 - Hypoxia-inducible factor prolyl hydroxylase 1 - HIF-PH1 - HIF-prolyl hydroxylase 1 - HPH-1 - Prolyl hydroxylase domain-containing protein 1 {ECO:0000303\|PubMed:11595184} - PHD1 {ECO:0000303\|PubMed:11595184}
Gene names	EGLN2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96KS0

5 N-termini

8 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDSPCQPQPL SQALPQLPGS SSEPLEPEPG RARMGVESYL PCPLLPSYHC PGVPSEASAG
        70         80         90        100        110        120
SGTPRATATS TTASPLRDGF GGQDGGELRP LQSEGAAALV TKGCQRLAAQ GARPEAPKRK
       130        140        150        160        170        180
WAEDGGDAPS PSKRPWARQE NQEAEREGGM SCSCSSGSGE ASAGLMEEAL PSAPERLALD
       190        200        210        220        230        240
YIVPCMRYYG ICVKDSFLGA ALGGRVLAEV EALKRGGRLR DGQLVSQRAI PPRSIRGDQI
       250        260        270        280        290        300
AWVEGHEPGC RSIGALMAHV DAVIRHCAGR LGSYVINGRT KAMVACYPGN GLGYVRHVDN
       310        320        330        340        350        360
PHGDGRCITC IYYLNQNWDV KVHGGLLQIF PEGRPVVANI EPLFDRLLIF WSDRRNPHEV
       370        380        390        400
KPAYATRYAI TVWYFDAKER AAAKDKYQLA SGQKGVQVPV SQPPTPT

Isoforms

- Isoform p40 of Egl nine homolog 2

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

5 N-termini - 8 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96KS0-1-unknown	MDSPCQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96KS0-34-unknown	MGVESY...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt73730
Q96KS0-240-unknown	IAWVEG...	240	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472991
Q96KS0-240-unknown	IAWVEG...	240	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198379
Q96KS0-283-unknown	MVACYP...	283	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472414
Q96KS0-283-unknown	MVACYP...	283	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198713
Q96KS0-357-unknown	PHEVKP...	357	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471740
Q96KS0-357-unknown	PHEVKP...	357	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199142

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPRATA	67	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472870
...TPRATA	67	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154003
...ATSTTA	72	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472146
...ATSTTA	72	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154063
...ASPLRD	77	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469272
...ASPLRD	77	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154097
...QDGGEL	87	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470968
...QDGGEL	87	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154220
...PLQSEG	94	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469323
...PLQSEG	94	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154298
...AALVTK	101	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471568
...AALVTK	101	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154392
...PWARQE	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471546
...PWARQE	139	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154832
...PPTPT	407	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PPTPT	407	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69348

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)