Q96M02: (E2-independent) E3 ubiquitin-conjugating enzyme FATS {ECO:0000305}

General Information

Protein names	- (E2-independent) E3 ubiquitin-conjugating enzyme FATS {ECO:0000305} - 2.3.2.- {ECO:0000250\|UniProtKB:D2J0Y4} - Centrosomal protein C10orf90 {ECO:0000305} - E2/E3 hybrid ubiquitin-protein ligase FATS {ECO:0000305} - Fragile-site associated tumor suppressor homolog {ECO:0000250\|UniProtKB:D2J0Y4} - FATS {ECO:0000250\|UniProtKB:D2J0Y4}
Gene names	C10orf90
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96M02

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Centrosomal protein C10orf90 - Isoform 2 of (E2-independent) E3 ubiquitin-conjugating enzyme FATS

Sequence View

        10         20         30         40         50         60
MLKLSGEGLR DSYHSRRDQI ALKNLQSDVT EAKSDFTKET LASQNTKMIS SIVISQMIDE
        70         80         90        100        110        120
NKSRENRASL PLPCAIAQSR AHHAKQSLAN RSGVNIHRAF ALLPGRLGIP APSDERGPEA
       130        140        150        160        170        180
ELPPKEERPC GGPRRGFASI TITARRVGPP ARALVWGTAG DSLCPKCRAE DTLFQAPPAL
       190        200        210        220        230        240
ANGAHPGRHQ RSFACTEFSR NSSVVRLKVP EAHTGLCERR KYWVTHADDK ETSFSPDTPL
       250        260        270        280        290        300
SGKSPLVFSS CVHLRVSQQC PDSIYYVDKS LSVPIEPPQI ASPKMHRSVL SLNLNCSSHR
       310        320        330        340        350        360
LTADGVDGLV NREPISEALK QELLEGDQDL VGQRWNPGLQ ESHLKETPSL RRVHLGTGAC
       370        380        390        400        410        420
PWSGSFPLEN TELANVGANQ VTVRKGEKDH TTHCHASDHA NQLSIHIPGW SYRAVHTKVF
       430        440        450        460        470        480
SGSSKRQQGE VCMTVSAPPV EQKPTRHFLP IGDSSPSDDC LSRDLSEPTE RRHQSFLKPR
       490        500        510        520        530        540
ILFPGFLCPL QDVCASLQED NGVQIESKFP KGDYTCCDLV VKIKECKKSE DPTTPEPSPA
       550        560        570        580        590        600
APSPAPRDGA GSPGLSEDCS ESQQTPARSL TLQEALEVRK PQFISRSQER LKKLEHMVQQ
       610        620        630        640        650        660
RKAQRKEDLR QKQSLLPIRT SKKQFTIPHP LSDNLFKPKE RCISEKEMHM RSKRIYDNLP
       670        680        690
EVKKKKEEQR KRVILQSNRL RAEVFKKQLL DQLLQRNAV         10         20         30         40         50         60
MLKLSGEGLR DSYHSRRDQI ALKNLQSDVT EAKSDFTKET LASQNTKMIS SIVISQMIDE
        70         80         90        100        110        120
NKSRENRASL PLPCAIAQSR AHHAKQSLAN RSGVNIHRAF ALLPGRLGIP APSDERGPEA
       130        140        150        160        170        180
ELPPKEERPC GGPRRGFASI TITARRVGPP ARALVWGTAG DSLCPKCRAE DTLFQAPPAL
       190        200        210        220        230        240
ANGAHPGRHQ RSFACTEFSR NSSVVRLKVP EAHTGLCERR KYWVTHADDK ETSFSPDTPL
       250        260        270        280        290        300
SGKSPLVFSS CVHLRVSQQC PDSIYYVDKS LSVPIEPPQI ASPKMHRSVL SLNLNCSSHR
       310        320        330        340        350        360
LTADGVDGLV NREPISEALK QELLEGDQDL VGQRWNPGLQ ESHLKETPSL RRVHLGTGAC
       370        380        390        400        410        420
PWSGSFPLEN TELANVGANQ VTVRKGEKDH TTHCHASDHA NQLSIHIPGW SYRAVHTKVF
       430        440        450        460        470        480
SGSSKRQQGE VCMTVSAPPV EQKPTRHFLP IGDSSPSDDC LSRDLSEPTE RRHQSFLKPR
       490        500        510        520        530        540
ILFPGFLCPL QDVCASLQED NGVQIESKFP KGDYTCCDLV VKIKECKKSE DPTTPEPSPA
       550        560        570        580        590        600
APSPAPRDGA GSPGLSEDCS ESQQTPARSL TLQEALEVRK PQFISRSQER LKKLEHMVQQ
       610        620        630        640        650        660
RKAQRKEDLR QKQSLLPIRT SKKQFTIPHP LSDNLFKPKE RCISEKEMHM RSKRIYDNLP
       670        680        690
EVKKKKEEQR KRVILQSNRL RAEVFKKQLL DQLLQRNAV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96M02-1-unknown	MLKLSG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96M02-1-unknown	MLKLSG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70721
Q96M02-48-unknown	MISSIV...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000349318
Q96M02-48-unknown	MISSIV...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474558
Q96M02-48-unknown	MISSIV...	48	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376459
Q96M02-48-unknown	MISSIV...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196081
Q96M02-597-unknown	MVQQRK...	597	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474753
Q96M02-597-unknown	MVQQRK...	597	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199963

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VHLRVS	256	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474558
...NLPEVK	662	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405995
...QRNAV	699	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QRNAV	699	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66339

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)