Q96M86: Dynein heavy chain domain-containing protein 1
| Protein names | - Dynein heavy chain domain-containing protein 1 - Dynein heavy chain domain 1-like protein - Protein CCDC35 |
|---|---|
| Gene names | DNHD1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q96M86 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVPEERRVGL SSDETSSDSL KSWHSICVLD SKEQPLACQQ KQRQFVKPVT ESEQPTVLEL
70 80 90 100 110 120
LLAELRTLFS AVLQDSSPAA WRYLHAVLGL LPPYRELLVG HLDLLPFLEQ LYCWAPWVQT
130 140 150 160 170 180
HLHLDLLGAI VQAFPPDSSL LDSASHADCC PQKRRLHHRP PCPACPFVQA QWSRQQVKEE
190 200 210 220 230 240
LATWLRPLTL PELQRCLGIV GAQVALEEAV WLDGLSLLPL ALAADIPVRY ESSDTDNAEV
250 260 270 280 290 300
EPVGRKETRS QLDYEVPREK AFQKSSTGFS PETSFLDSQV MTALKMERYL KKIHFLYLNV
310 320 330 340 350 360
APSRYFRPYS LMVVPPDKVN PEHYIFSPFG ILHVHPVEGS ETMTLGTWHH HCVLWQQLQF
370 380 390 400 410 420
IPFFKYCLLR KSFTCWKKNV RLQGLHRLQK FLENHLLLAV PHFGAGLLHI SRLLQELHSV
430 440 450 460 470 480
SWLPQELDRC YELLDLQTAL AEEKHKALRL LHRCLNLCTS ILRLVHEDTY HMQQCLQERV
490 500 510 520 530 540
QNCDRIRTGQ GSIYLQRVQH KQLEQKLKQA EAWWLQLGKF ARLVDYMICQ SLISVLEEQI
550 560 570 580 590 600
TSFVANILQA PRQKPFLSSQ LVFDDHGQLS HVPCVENMIQ TLTGGLQSVK TSALQVVQSA
610 620 630 640 650 660
DLKTSSDSLY SEEEDEEEDS KDEFLMPKFQ GQPSDAVSIF CGPNVGLVWP WKSHPIAGIL
670 680 690 700 710 720
EVRGCRLRGQ YFPHNYKQLE EDLDNNPKIQ QALNIQQVLL EGVLCKVQEF CREHHWITGI
730 740 750 760 770 780
YEFLQSWGPQ KLEDMRGGPI KNYVTLVSRL NVWQARVSSM PIELLTKGGL LLLSCHDVQA
790 800 810 820 830 840
EMESKLNSIR KDILAHVQNE CWNLSQQLMT ELTDFMHIFR TINSDIHAIA QCTQKLNEAN
850 860 870 880 890 900
EQYVELEERM EYVRALHELI RNHFSLFSAE NEALDISVRR QFGESPIPPC PPPPQPHLLH
910 920 930 940 950 960
CPLLAPQLLD MWEAFQFEKS QASEFLLSKR HAIMPKLQQL MAAALAELEG LLAKALSGPF
970 980 990 1000 1010 1020
MDPTQDQRST EHQLVSLERQ FQNTVSDLSE LHHAYAIFTE DETPVPLPIC GTRPIVQQQR
1030 1040 1050 1060 1070 1080
IWHLYRVISE NISEWKCMAF AKFSPAMAQE KTEGWLTEAA RMSTTLELHS PVLQHCMRIL
1090 1100 1110 1120 1130 1140
GEFRSYLPLL TKLGSLHPQS LNCQCLLRAL GLGSLQTIEL LTLGQLLTYP LLEFADRINQ
1150 1160 1170 1180 1190 1200
VWQNENERIH AQETIRRLQR YWEARQLRLL NFILHVPYEP PASERSKRQV LRSPQWEVVD
1210 1220 1230 1240 1250 1260
KDSGTFILSD YSNLQDSIQE SLQVLSKILA IEKSGDLNKI ALEWVAIMHG LGALLEVWLT
1270 1280 1290 1300 1310 1320
FQQKWIFLNK VLHEMKIQFP NADLNSRFKV MDDQYRTLMR ISVADPMVLS LVVPSAERSP
1330 1340 1350 1360 1370 1380
YFQGQQLQQL LQAGSVELEG IIMSLESVLY GVCAHFPRLF FLSDSELVAL LAARLESCEA
1390 1400 1410 1420 1430 1440
QLWVRRCFPH VHAVSFRSCP TGEKNTDDWE SSPNTQTQVE ALAVLGAGGE EVKLQGPLPL
1450 1460 1470 1480 1490 1500
HPDLPKWLAS LEKCLRLALV HMLQGCVAAR LARGPSLGEA LKQLPKQNKL YLQLYVQHWI
1510 1520 1530 1540 1550 1560
DLVQAFPWQC VLVAEEVVWR AEMEEALLEW GTLAMVSMHM RKLEVLVNFM RAQRASQGGQ
1570 1580 1590 1600 1610 1620
SLPSVRQTSL LSALLVMAVT HRDIAQLLEQ HQVSDLTDFH WVRQLKYHLG SPHIIPKSPL
1630 1640 1650 1660 1670 1680
QSLKTIASSE PSLSPAACWI DVLGRSFLYN YEYLGPRLGP LPSLLPERPA LVLLLALEEV
1690 1700 1710 1720 1730 1740
ACGTVLGPNG VGKRAIVNSL AQALGRQLVM LPCSPQIEAQ CLSNYLNGAL QGGAWLLLEK
1750 1760 1770 1780 1790 1800
VHQLPPGLLS ALGQRLGELH HLYAPLYQEA SRNTSTIDPT QPQLLGSSFF EKHHVSVRLG
1810 1820 1830 1840 1850 1860
YGCLLVLRAL SSAVPANLHL LLRPVALALP DLRQVAELTL LGAGMRDAFQ MATRLSKFFS
1870 1880 1890 1900 1910 1920
LERELVSGPL PCRLPLLKQI LEDTIRTLNV TKEEPKCQKP RSLAAIEEAA LLRSPLFSIL
1930 1940 1950 1960 1970 1980
NGLHLHNLRG LLCALFPSAS QVLAEPMTYK LMKPLVVEEL QQVGLDPSPD ILGSLEQLSQ
1990 2000 2010 2020 2030 2040
ALSRASGILL LGPAGSGKTT CWHSLFKIQN RLAAMEDTST QGCQPVEITH LYPSGLSPQE
2050 2060 2070 2080 2090 2100
FLGWLEGSCW HHGIFPKVLR AAGQCNNMGQ KRQTEESIGI QHWIICDGAS NGAWLDSITC
2110 2120 2130 2140 2150 2160
LLSELPQLSL PSGQQIARPP GTFLLMEVAD TTGISPTVVG CCALVWCGGE QTWQCILSAL
2170 2180 2190 2200 2210 2220
MASLPYEYRL QHRTVAELNH MAEVLVPATL RFLTCQGVSS LLQVHGQQAV CAGVAEVTSM
2230 2240 2250 2260 2270 2280
ARILHSLLDL HLRLKEEKAP GPEDLSYSDP VAQSFRSSKS SFLNRSQVDS DDVPDKCREH
2290 2300 2310 2320 2330 2340
LLAVSSFLFA LIWGFGAHLP SRFWPIFDTF IRDSISRLSN YPEPPPSALV FDLHVSPEDG
2350 2360 2370 2380 2390 2400
TLVPFTGQYL SSHIKGTLGT FHPSIQTERL LYVVDLLLSG GQPVLLAGEA ATGKSAFVEV
2410 2420 2430 2440 2450 2460
LVEPHHPYIY SPIHPAFSSS HLRLLLSRGI QGQTQASPQP GHHQDSKPSL LFLLEDLHLA
2470 2480 2490 2500 2510 2520
TSDPEKSCQP VLETLRQAMD GTVYAHSTLE LQTLQPTVNF LATVTVPGYC ERPLCPRLFR
2530 2540 2550 2560 2570 2580
LFTVLALESM TQATLLERHV PIIQAWLERF PSVERERALA RGLVRASVEA WEAVCNCFMP
2590 2600 2610 2620 2630 2640
SPLHPHYHFS LHSVSHLLSS LQLLPNRTGS RGFVDYPNHQ EHLRRVSGLR GTCLTVMMAT
2650 2660 2670 2680 2690 2700
RNVVRLWLHE AQRTFCDRLD SPRERSYCAK LLLVVAQSVF CCGPGPQHLG KDHQESEEEE
2710 2720 2730 2740 2750 2760
EEERVPEVES EGELAQWEDF SNSNSETEEE EEPYGLQVAR VSNSRDPSLT PSIGPVSRGM
2770 2780 2790 2800 2810 2820
KESISHKIRQ EKGTRASNYR LQVRRSFKTW WQKKPQMDLI SPLLLPVLLL HPQEKPSDLV
2830 2840 2850 2860 2870 2880
FSQELILGPN SETPNLYLER QWEKLEEQLA TSAAQLKLSP HLARCHSMAQ HVARLVRVLA
2890 2900 2910 2920 2930 2940
RPRQHGLLLS GALGTGRHTA ITLASSICQA HFFHLPSGSE EAILQCLRDA SWHAGMLSQP
2950 2960 2970 2980 2990 3000
VALLVPSGVD LTTLHRLLAL ATSGSFPGQY TEADLDRIGE HLPRENLGVK QNIKKEMVLQ
3010 3020 3030 3040 3050 3060
RFHQQVCSHL HLFFLIGDKQ AHKQLPSTLF LRLLQLATAS IDRYEPWDQA ALAKVAQHHL
3070 3080 3090 3100 3110 3120
EGAQSVPLDD GSWKYPDLQA SIPSVAKAMA LIHLSATHYH EHLCPALPLV TPKTFLDFLD
3130 3140 3150 3160 3170 3180
TFLMLQQQTI LKIKNKAQRV QNALENLRML IKEHGTHANL IFDLEQQLKD SGKSLSMFQQ
3190 3200 3210 3220 3230 3240
QLEQSKLLYK QQLEECRHQE NLIENLARQR DALQAQREAF LEQMSKAFLE PLSQLQVADF
3250 3260 3270 3280 3290 3300
EEIRSYRAPP ESVVRVTDAM CDLFHHETGW ASAKQLLCTE DFYQELVFFP KEKITDSELI
3310 3320 3330 3340 3350 3360
KLHLILKAPG MDDAALRAVS RPAASLAAWL WAVLHYGLAH CRGLPTDLLL QQVEATLTRE
3370 3380 3390 3400 3410 3420
QARLGYYQFQ AQETLEHNLA LAKMVEDAQA SHNCVAKTLS QAQCGQYHKW PMKAALLTPM
3430 3440 3450 3460 3470 3480
RAWTTQLQKL KGRCMTVFGD TLLCSAAIIY LGPFPPLRRQ ELLDEWLALC RGFQEALGPD
3490 3500 3510 3520 3530 3540
DVAQALKRKQ KSVSIPPKNP LLATHSPFSI LSLLSSESEQ YQWDGNLKPQ AKSAHLAGLL
3550 3560 3570 3580 3590 3600
LRSPTHYSSC RWPLLLDPSN EALIWLDPLP LEENRSFAPA LTEGRGKGLM RNQKRESKTD
3610 3620 3630 3640 3650 3660
MKEEDDESEE SNEAEDQTKE QKAEERKNEQ EKEQEENEEK EEEKTESQGS KPAYETQLPS
3670 3680 3690 3700 3710 3720
LPYLSVLSGA DPELGSQLQE AAACGLPVLL TNVELGLGCE ELQWLLQREQ LSPPQVQPGF
3730 3740 3750 3760 3770 3780
CLYLSTTLSL CAMEKVLGCE LLKGLNVLDL GLNMEILEEQ MLHEILCREY PELETRWQDL
3790 3800 3810 3820 3830 3840
KIRALDTCKA VEAAEERLLT MLLFQNPKRQ KPAKFLRNIV RAQGKLCQLR AHCEELEGQK
3850 3860 3870 3880 3890 3900
LQEMVLWAPY RPVVWHGMAM VKALSQLQNL LPLFCMSPEN WLAVTKQALD SMKPREINHG
3910 3920 3930 3940 3950 3960
EDLASHLLQL RAHLTRQLLG STVTALGLTQ VPLVGALGAL ALLQATGKAS ELERLALWPG
3970 3980 3990 4000 4010 4020
LAASPSTVHS KPVSDVARPA WLGPKAWHEC EMLELLPPFV GLCASLAGHS SAWQAYLSLS
4030 4040 4050 4060 4070 4080
STVLGPAPGP GPEPLSLLQK LILWRVLRPE CLAGALADFT TSLLGRPLDE NTYAPTMPFK
4090 4100 4110 4120 4130 4140
HSQATQPMLI LLPPPGHPSA TLHPLTVIQK LAAKYQQGQK QLQVIALGSE AWDPVSVVVS
4150 4160 4170 4180 4190 4200
TLSQAMYEGH WLVLDNCHLM PHWPKELLQL LLELLGRAKV VADLESEQLL DQPESRNVST
4210 4220 4230 4240 4250 4260
VHRDFRLWLI VPAESSASLP AVLTQHSMPV FWNQSLELGH VLIDSVELAQ QVLYMQPPTQ
4270 4280 4290 4300 4310 4320
ALPLLLLHGL LLHRQLYGTR LQAHRGRWSQ VTLTQVLQTQ DQLWASLSNP RAAMQELAAS
4330 4340 4350 4360 4370 4380
VFYGGPLGDT EDREALISLT QACLSPSSGS WVQPHTPQSL LATLMPLPEL RELDAMAECK
4390 4400 4410 4420 4430 4440
AQMHLLPSPP EPRLCGLSEG PQAWLLRRQS RALLSALQRS SPVWVPESRR GAQLAERRLR
4450 4460 4470 4480 4490 4500
QRLVQVNRRL ESLQDLLTHV IRQDESDAPW SVLGPNARRP LEGVLETEAL ELSQLVGTLQ
4510 4520 4530 4540 4550 4560
RDLDCLLQQL KGAPPCPSRR CAAVAHALWT GRLPLPWRPH APAGPQPPWH WLRQLSRRGQ
4570 4580 4590 4600 4610 4620
LLVRYLGVGA DASSDVPERV FHLSAFRHPR RLLLALRGEA ALDQNVPSSN FPGSRGSVSS
4630 4640 4650 4660 4670 4680
QLQYKRLEMN SNPLHFRVEN GPNPTVPERG LLLIGLQVLH AEWDPIAGAL QDSPSSQPSP
4690 4700 4710 4720 4730 4740
LPPVSISTQA PGTSDLPAPA DLTVYSCPVY MGGPLGTAKL QSRNIVMHLP LPTKLTPNTC
4750
VQRRVHVCSP PLS
Isoforms
- Isoform 2 of Dynein heavy chain domain-containing protein 1 - Isoform 3 of Dynein heavy chain domain-containing protein 1Sequence View
10 20 30 40 50 60
MVPEERRVGL SSDETSSDSL KSWHSICVLD SKEQPLACQQ KQRQFVKPVT ESEQPTVLEL
70 80 90 100 110 120
LLAELRTLFS AVLQDSSPAA WRYLHAVLGL LPPYRELLVG HLDLLPFLEQ LYCWAPWVQT
130 140 150 160 170 180
HLHLDLLGAI VQAFPPDSSL LDSASHADCC PQKRRLHHRP PCPACPFVQA QWSRQQVKEE
190 200 210 220 230 240
LATWLRPLTL PELQRCLGIV GAQVALEEAV WLDGLSLLPL ALAADIPVRY ESSDTDNAEV
250 260 270 280 290 300
EPVGRKETRS QLDYEVPREK AFQKSSTGFS PETSFLDSQV MTALKMERYL KKIHFLYLNV
310 320 330 340 350 360
APSRYFRPYS LMVVPPDKVN PEHYIFSPFG ILHVHPVEGS ETMTLGTWHH HCVLWQQLQF
370 380 390 400 410 420
IPFFKYCLLR KSFTCWKKNV RLQGLHRLQK FLENHLLLAV PHFGAGLLHI SRLLQELHSV
430 440 450 460 470 480
SWLPQELDRC YELLDLQTAL AEEKHKALRL LHRCLNLCTS ILRLVHEDTY HMQQCLQERV
490 500 510 520 530 540
QNCDRIRTGQ GSIYLQRVQH KQLEQKLKQA EAWWLQLGKF ARLVDYMICQ SLISVLEEQI
550 560 570 580 590 600
TSFVANILQA PRQKPFLSSQ LVFDDHGQLS HVPCVENMIQ TLTGGLQSVK TSALQVVQSA
610 620 630 640 650 660
DLKTSSDSLY SEEEDEEEDS KDEFLMPKFQ GQPSDAVSIF CGPNVGLVWP WKSHPIAGIL
670 680 690 700 710 720
EVRGCRLRGQ YFPHNYKQLE EDLDNNPKIQ QALNIQQVLL EGVLCKVQEF CREHHWITGI
730 740 750 760 770 780
YEFLQSWGPQ KLEDMRGGPI KNYVTLVSRL NVWQARVSSM PIELLTKGGL LLLSCHDVQA
790 800 810 820 830 840
EMESKLNSIR KDILAHVQNE CWNLSQQLMT ELTDFMHIFR TINSDIHAIA QCTQKLNEAN
850 860 870 880 890 900
EQYVELEERM EYVRALHELI RNHFSLFSAE NEALDISVRR QFGESPIPPC PPPPQPHLLH
910 920 930 940 950 960
CPLLAPQLLD MWEAFQFEKS QASEFLLSKR HAIMPKLQQL MAAALAELEG LLAKALSGPF
970 980 990 1000 1010 1020
MDPTQDQRST EHQLVSLERQ FQNTVSDLSE LHHAYAIFTE DETPVPLPIC GTRPIVQQQR
1030 1040 1050 1060 1070 1080
IWHLYRVISE NISEWKCMAF AKFSPAMAQE KTEGWLTEAA RMSTTLELHS PVLQHCMRIL
1090 1100 1110 1120 1130 1140
GEFRSYLPLL TKLGSLHPQS LNCQCLLRAL GLGSLQTIEL LTLGQLLTYP LLEFADRINQ
1150 1160 1170 1180 1190 1200
VWQNENERIH AQETIRRLQR YWEARQLRLL NFILHVPYEP PASERSKRQV LRSPQWEVVD
1210 1220 1230 1240 1250 1260
KDSGTFILSD YSNLQDSIQE SLQVLSKILA IEKSGDLNKI ALEWVAIMHG LGALLEVWLT
1270 1280 1290 1300 1310 1320
FQQKWIFLNK VLHEMKIQFP NADLNSRFKV MDDQYRTLMR ISVADPMVLS LVVPSAERSP
1330 1340 1350 1360 1370 1380
YFQGQQLQQL LQAGSVELEG IIMSLESVLY GVCAHFPRLF FLSDSELVAL LAARLESCEA
1390 1400 1410 1420 1430 1440
QLWVRRCFPH VHAVSFRSCP TGEKNTDDWE SSPNTQTQVE ALAVLGAGGE EVKLQGPLPL
1450 1460 1470 1480 1490 1500
HPDLPKWLAS LEKCLRLALV HMLQGCVAAR LARGPSLGEA LKQLPKQNKL YLQLYVQHWI
1510 1520 1530 1540 1550 1560
DLVQAFPWQC VLVAEEVVWR AEMEEALLEW GTLAMVSMHM RKLEVLVNFM RAQRASQGGQ
1570 1580 1590 1600 1610 1620
SLPSVRQTSL LSALLVMAVT HRDIAQLLEQ HQVSDLTDFH WVRQLKYHLG SPHIIPKSPL
1630 1640 1650 1660 1670 1680
QSLKTIASSE PSLSPAACWI DVLGRSFLYN YEYLGPRLGP LPSLLPERPA LVLLLALEEV
1690 1700 1710 1720 1730 1740
ACGTVLGPNG VGKRAIVNSL AQALGRQLVM LPCSPQIEAQ CLSNYLNGAL QGGAWLLLEK
1750 1760 1770 1780 1790 1800
VHQLPPGLLS ALGQRLGELH HLYAPLYQEA SRNTSTIDPT QPQLLGSSFF EKHHVSVRLG
1810 1820 1830 1840 1850 1860
YGCLLVLRAL SSAVPANLHL LLRPVALALP DLRQVAELTL LGAGMRDAFQ MATRLSKFFS
1870 1880 1890 1900 1910 1920
LERELVSGPL PCRLPLLKQI LEDTIRTLNV TKEEPKCQKP RSLAAIEEAA LLRSPLFSIL
1930 1940 1950 1960 1970 1980
NGLHLHNLRG LLCALFPSAS QVLAEPMTYK LMKPLVVEEL QQVGLDPSPD ILGSLEQLSQ
1990 2000 2010 2020 2030 2040
ALSRASGILL LGPAGSGKTT CWHSLFKIQN RLAAMEDTST QGCQPVEITH LYPSGLSPQE
2050 2060 2070 2080 2090 2100
FLGWLEGSCW HHGIFPKVLR AAGQCNNMGQ KRQTEESIGI QHWIICDGAS NGAWLDSITC
2110 2120 2130 2140 2150 2160
LLSELPQLSL PSGQQIARPP GTFLLMEVAD TTGISPTVVG CCALVWCGGE QTWQCILSAL
2170 2180 2190 2200 2210 2220
MASLPYEYRL QHRTVAELNH MAEVLVPATL RFLTCQGVSS LLQVHGQQAV CAGVAEVTSM
2230 2240 2250 2260 2270 2280
ARILHSLLDL HLRLKEEKAP GPEDLSYSDP VAQSFRSSKS SFLNRSQVDS DDVPDKCREH
2290 2300 2310 2320 2330 2340
LLAVSSFLFA LIWGFGAHLP SRFWPIFDTF IRDSISRLSN YPEPPPSALV FDLHVSPEDG
2350 2360 2370 2380 2390 2400
TLVPFTGQYL SSHIKGTLGT FHPSIQTERL LYVVDLLLSG GQPVLLAGEA ATGKSAFVEV
2410 2420 2430 2440 2450 2460
LVEPHHPYIY SPIHPAFSSS HLRLLLSRGI QGQTQASPQP GHHQDSKPSL LFLLEDLHLA
2470 2480 2490 2500 2510 2520
TSDPEKSCQP VLETLRQAMD GTVYAHSTLE LQTLQPTVNF LATVTVPGYC ERPLCPRLFR
2530 2540 2550 2560 2570 2580
LFTVLALESM TQATLLERHV PIIQAWLERF PSVERERALA RGLVRASVEA WEAVCNCFMP
2590 2600 2610 2620 2630 2640
SPLHPHYHFS LHSVSHLLSS LQLLPNRTGS RGFVDYPNHQ EHLRRVSGLR GTCLTVMMAT
2650 2660 2670 2680 2690 2700
RNVVRLWLHE AQRTFCDRLD SPRERSYCAK LLLVVAQSVF CCGPGPQHLG KDHQESEEEE
2710 2720 2730 2740 2750 2760
EEERVPEVES EGELAQWEDF SNSNSETEEE EEPYGLQVAR VSNSRDPSLT PSIGPVSRGM
2770 2780 2790 2800 2810 2820
KESISHKIRQ EKGTRASNYR LQVRRSFKTW WQKKPQMDLI SPLLLPVLLL HPQEKPSDLV
2830 2840 2850 2860 2870 2880
FSQELILGPN SETPNLYLER QWEKLEEQLA TSAAQLKLSP HLARCHSMAQ HVARLVRVLA
2890 2900 2910 2920 2930 2940
RPRQHGLLLS GALGTGRHTA ITLASSICQA HFFHLPSGSE EAILQCLRDA SWHAGMLSQP
2950 2960 2970 2980 2990 3000
VALLVPSGVD LTTLHRLLAL ATSGSFPGQY TEADLDRIGE HLPRENLGVK QNIKKEMVLQ
3010 3020 3030 3040 3050 3060
RFHQQVCSHL HLFFLIGDKQ AHKQLPSTLF LRLLQLATAS IDRYEPWDQA ALAKVAQHHL
3070 3080 3090 3100 3110 3120
EGAQSVPLDD GSWKYPDLQA SIPSVAKAMA LIHLSATHYH EHLCPALPLV TPKTFLDFLD
3130 3140 3150 3160 3170 3180
TFLMLQQQTI LKIKNKAQRV QNALENLRML IKEHGTHANL IFDLEQQLKD SGKSLSMFQQ
3190 3200 3210 3220 3230 3240
QLEQSKLLYK QQLEECRHQE NLIENLARQR DALQAQREAF LEQMSKAFLE PLSQLQVADF
3250 3260 3270 3280 3290 3300
EEIRSYRAPP ESVVRVTDAM CDLFHHETGW ASAKQLLCTE DFYQELVFFP KEKITDSELI
3310 3320 3330 3340 3350 3360
KLHLILKAPG MDDAALRAVS RPAASLAAWL WAVLHYGLAH CRGLPTDLLL QQVEATLTRE
3370 3380 3390 3400 3410 3420
QARLGYYQFQ AQETLEHNLA LAKMVEDAQA SHNCVAKTLS QAQCGQYHKW PMKAALLTPM
3430 3440 3450 3460 3470 3480
RAWTTQLQKL KGRCMTVFGD TLLCSAAIIY LGPFPPLRRQ ELLDEWLALC RGFQEALGPD
3490 3500 3510 3520 3530 3540
DVAQALKRKQ KSVSIPPKNP LLATHSPFSI LSLLSSESEQ YQWDGNLKPQ AKSAHLAGLL
3550 3560 3570 3580 3590 3600
LRSPTHYSSC RWPLLLDPSN EALIWLDPLP LEENRSFAPA LTEGRGKGLM RNQKRESKTD
3610 3620 3630 3640 3650 3660
MKEEDDESEE SNEAEDQTKE QKAEERKNEQ EKEQEENEEK EEEKTESQGS KPAYETQLPS
3670 3680 3690 3700 3710 3720
LPYLSVLSGA DPELGSQLQE AAACGLPVLL TNVELGLGCE ELQWLLQREQ LSPPQVQPGF
3730 3740 3750 3760 3770 3780
CLYLSTTLSL CAMEKVLGCE LLKGLNVLDL GLNMEILEEQ MLHEILCREY PELETRWQDL
3790 3800 3810 3820 3830 3840
KIRALDTCKA VEAAEERLLT MLLFQNPKRQ KPAKFLRNIV RAQGKLCQLR AHCEELEGQK
3850 3860 3870 3880 3890 3900
LQEMVLWAPY RPVVWHGMAM VKALSQLQNL LPLFCMSPEN WLAVTKQALD SMKPREINHG
3910 3920 3930 3940 3950 3960
EDLASHLLQL RAHLTRQLLG STVTALGLTQ VPLVGALGAL ALLQATGKAS ELERLALWPG
3970 3980 3990 4000 4010 4020
LAASPSTVHS KPVSDVARPA WLGPKAWHEC EMLELLPPFV GLCASLAGHS SAWQAYLSLS
4030 4040 4050 4060 4070 4080
STVLGPAPGP GPEPLSLLQK LILWRVLRPE CLAGALADFT TSLLGRPLDE NTYAPTMPFK
4090 4100 4110 4120 4130 4140
HSQATQPMLI LLPPPGHPSA TLHPLTVIQK LAAKYQQGQK QLQVIALGSE AWDPVSVVVS
4150 4160 4170 4180 4190 4200
TLSQAMYEGH WLVLDNCHLM PHWPKELLQL LLELLGRAKV VADLESEQLL DQPESRNVST
4210 4220 4230 4240 4250 4260
VHRDFRLWLI VPAESSASLP AVLTQHSMPV FWNQSLELGH VLIDSVELAQ QVLYMQPPTQ
4270 4280 4290 4300 4310 4320
ALPLLLLHGL LLHRQLYGTR LQAHRGRWSQ VTLTQVLQTQ DQLWASLSNP RAAMQELAAS
4330 4340 4350 4360 4370 4380
VFYGGPLGDT EDREALISLT QACLSPSSGS WVQPHTPQSL LATLMPLPEL RELDAMAECK
4390 4400 4410 4420 4430 4440
AQMHLLPSPP EPRLCGLSEG PQAWLLRRQS RALLSALQRS SPVWVPESRR GAQLAERRLR
4450 4460 4470 4480 4490 4500
QRLVQVNRRL ESLQDLLTHV IRQDESDAPW SVLGPNARRP LEGVLETEAL ELSQLVGTLQ
4510 4520 4530 4540 4550 4560
RDLDCLLQQL KGAPPCPSRR CAAVAHALWT GRLPLPWRPH APAGPQPPWH WLRQLSRRGQ
4570 4580 4590 4600 4610 4620
LLVRYLGVGA DASSDVPERV FHLSAFRHPR RLLLALRGEA ALDQNVPSSN FPGSRGSVSS
4630 4640 4650 4660 4670 4680
QLQYKRLEMN SNPLHFRVEN GPNPTVPERG LLLIGLQVLH AEWDPIAGAL QDSPSSQPSP
4690 4700 4710 4720 4730 4740
LPPVSISTQA PGTSDLPAPA DLTVYSCPVY MGGPLGTAKL QSRNIVMHLP LPTKLTPNTC
4750
VQRRVHVCSP PLS
10 20 30 40 50 60
MVPEERRVGL SSDETSSDSL KSWHSICVLD SKEQPLACQQ KQRQFVKPVT ESEQPTVLEL
70 80 90 100 110 120
LLAELRTLFS AVLQDSSPAA WRYLHAVLGL LPPYRELLVG HLDLLPFLEQ LYCWAPWVQT
130 140 150 160 170 180
HLHLDLLGAI VQAFPPDSSL LDSASHADCC PQKRRLHHRP PCPACPFVQA QWSRQQVKEE
190 200 210 220 230 240
LATWLRPLTL PELQRCLGIV GAQVALEEAV WLDGLSLLPL ALAADIPVRY ESSDTDNAEV
250 260 270 280 290 300
EPVGRKETRS QLDYEVPREK AFQKSSTGFS PETSFLDSQV MTALKMERYL KKIHFLYLNV
310 320 330 340 350 360
APSRYFRPYS LMVVPPDKVN PEHYIFSPFG ILHVHPVEGS ETMTLGTWHH HCVLWQQLQF
370 380 390 400 410 420
IPFFKYCLLR KSFTCWKKNV RLQGLHRLQK FLENHLLLAV PHFGAGLLHI SRLLQELHSV
430 440 450 460 470 480
SWLPQELDRC YELLDLQTAL AEEKHKALRL LHRCLNLCTS ILRLVHEDTY HMQQCLQERV
490 500 510 520 530 540
QNCDRIRTGQ GSIYLQRVQH KQLEQKLKQA EAWWLQLGKF ARLVDYMICQ SLISVLEEQI
550 560 570 580 590 600
TSFVANILQA PRQKPFLSSQ LVFDDHGQLS HVPCVENMIQ TLTGGLQSVK TSALQVVQSA
610 620 630 640 650 660
DLKTSSDSLY SEEEDEEEDS KDEFLMPKFQ GQPSDAVSIF CGPNVGLVWP WKSHPIAGIL
670 680 690 700 710 720
EVRGCRLRGQ YFPHNYKQLE EDLDNNPKIQ QALNIQQVLL EGVLCKVQEF CREHHWITGI
730 740 750 760 770 780
YEFLQSWGPQ KLEDMRGGPI KNYVTLVSRL NVWQARVSSM PIELLTKGGL LLLSCHDVQA
790 800 810 820 830 840
EMESKLNSIR KDILAHVQNE CWNLSQQLMT ELTDFMHIFR TINSDIHAIA QCTQKLNEAN
850 860 870 880 890 900
EQYVELEERM EYVRALHELI RNHFSLFSAE NEALDISVRR QFGESPIPPC PPPPQPHLLH
910 920 930 940 950 960
CPLLAPQLLD MWEAFQFEKS QASEFLLSKR HAIMPKLQQL MAAALAELEG LLAKALSGPF
970 980 990 1000 1010 1020
MDPTQDQRST EHQLVSLERQ FQNTVSDLSE LHHAYAIFTE DETPVPLPIC GTRPIVQQQR
1030 1040 1050 1060 1070 1080
IWHLYRVISE NISEWKCMAF AKFSPAMAQE KTEGWLTEAA RMSTTLELHS PVLQHCMRIL
1090 1100 1110 1120 1130 1140
GEFRSYLPLL TKLGSLHPQS LNCQCLLRAL GLGSLQTIEL LTLGQLLTYP LLEFADRINQ
1150 1160 1170 1180 1190 1200
VWQNENERIH AQETIRRLQR YWEARQLRLL NFILHVPYEP PASERSKRQV LRSPQWEVVD
1210 1220 1230 1240 1250 1260
KDSGTFILSD YSNLQDSIQE SLQVLSKILA IEKSGDLNKI ALEWVAIMHG LGALLEVWLT
1270 1280 1290 1300 1310 1320
FQQKWIFLNK VLHEMKIQFP NADLNSRFKV MDDQYRTLMR ISVADPMVLS LVVPSAERSP
1330 1340 1350 1360 1370 1380
YFQGQQLQQL LQAGSVELEG IIMSLESVLY GVCAHFPRLF FLSDSELVAL LAARLESCEA
1390 1400 1410 1420 1430 1440
QLWVRRCFPH VHAVSFRSCP TGEKNTDDWE SSPNTQTQVE ALAVLGAGGE EVKLQGPLPL
1450 1460 1470 1480 1490 1500
HPDLPKWLAS LEKCLRLALV HMLQGCVAAR LARGPSLGEA LKQLPKQNKL YLQLYVQHWI
1510 1520 1530 1540 1550 1560
DLVQAFPWQC VLVAEEVVWR AEMEEALLEW GTLAMVSMHM RKLEVLVNFM RAQRASQGGQ
1570 1580 1590 1600 1610 1620
SLPSVRQTSL LSALLVMAVT HRDIAQLLEQ HQVSDLTDFH WVRQLKYHLG SPHIIPKSPL
1630 1640 1650 1660 1670 1680
QSLKTIASSE PSLSPAACWI DVLGRSFLYN YEYLGPRLGP LPSLLPERPA LVLLLALEEV
1690 1700 1710 1720 1730 1740
ACGTVLGPNG VGKRAIVNSL AQALGRQLVM LPCSPQIEAQ CLSNYLNGAL QGGAWLLLEK
1750 1760 1770 1780 1790 1800
VHQLPPGLLS ALGQRLGELH HLYAPLYQEA SRNTSTIDPT QPQLLGSSFF EKHHVSVRLG
1810 1820 1830 1840 1850 1860
YGCLLVLRAL SSAVPANLHL LLRPVALALP DLRQVAELTL LGAGMRDAFQ MATRLSKFFS
1870 1880 1890 1900 1910 1920
LERELVSGPL PCRLPLLKQI LEDTIRTLNV TKEEPKCQKP RSLAAIEEAA LLRSPLFSIL
1930 1940 1950 1960 1970 1980
NGLHLHNLRG LLCALFPSAS QVLAEPMTYK LMKPLVVEEL QQVGLDPSPD ILGSLEQLSQ
1990 2000 2010 2020 2030 2040
ALSRASGILL LGPAGSGKTT CWHSLFKIQN RLAAMEDTST QGCQPVEITH LYPSGLSPQE
2050 2060 2070 2080 2090 2100
FLGWLEGSCW HHGIFPKVLR AAGQCNNMGQ KRQTEESIGI QHWIICDGAS NGAWLDSITC
2110 2120 2130 2140 2150 2160
LLSELPQLSL PSGQQIARPP GTFLLMEVAD TTGISPTVVG CCALVWCGGE QTWQCILSAL
2170 2180 2190 2200 2210 2220
MASLPYEYRL QHRTVAELNH MAEVLVPATL RFLTCQGVSS LLQVHGQQAV CAGVAEVTSM
2230 2240 2250 2260 2270 2280
ARILHSLLDL HLRLKEEKAP GPEDLSYSDP VAQSFRSSKS SFLNRSQVDS DDVPDKCREH
2290 2300 2310 2320 2330 2340
LLAVSSFLFA LIWGFGAHLP SRFWPIFDTF IRDSISRLSN YPEPPPSALV FDLHVSPEDG
2350 2360 2370 2380 2390 2400
TLVPFTGQYL SSHIKGTLGT FHPSIQTERL LYVVDLLLSG GQPVLLAGEA ATGKSAFVEV
2410 2420 2430 2440 2450 2460
LVEPHHPYIY SPIHPAFSSS HLRLLLSRGI QGQTQASPQP GHHQDSKPSL LFLLEDLHLA
2470 2480 2490 2500 2510 2520
TSDPEKSCQP VLETLRQAMD GTVYAHSTLE LQTLQPTVNF LATVTVPGYC ERPLCPRLFR
2530 2540 2550 2560 2570 2580
LFTVLALESM TQATLLERHV PIIQAWLERF PSVERERALA RGLVRASVEA WEAVCNCFMP
2590 2600 2610 2620 2630 2640
SPLHPHYHFS LHSVSHLLSS LQLLPNRTGS RGFVDYPNHQ EHLRRVSGLR GTCLTVMMAT
2650 2660 2670 2680 2690 2700
RNVVRLWLHE AQRTFCDRLD SPRERSYCAK LLLVVAQSVF CCGPGPQHLG KDHQESEEEE
2710 2720 2730 2740 2750 2760
EEERVPEVES EGELAQWEDF SNSNSETEEE EEPYGLQVAR VSNSRDPSLT PSIGPVSRGM
2770 2780 2790 2800 2810 2820
KESISHKIRQ EKGTRASNYR LQVRRSFKTW WQKKPQMDLI SPLLLPVLLL HPQEKPSDLV
2830 2840 2850 2860 2870 2880
FSQELILGPN SETPNLYLER QWEKLEEQLA TSAAQLKLSP HLARCHSMAQ HVARLVRVLA
2890 2900 2910 2920 2930 2940
RPRQHGLLLS GALGTGRHTA ITLASSICQA HFFHLPSGSE EAILQCLRDA SWHAGMLSQP
2950 2960 2970 2980 2990 3000
VALLVPSGVD LTTLHRLLAL ATSGSFPGQY TEADLDRIGE HLPRENLGVK QNIKKEMVLQ
3010 3020 3030 3040 3050 3060
RFHQQVCSHL HLFFLIGDKQ AHKQLPSTLF LRLLQLATAS IDRYEPWDQA ALAKVAQHHL
3070 3080 3090 3100 3110 3120
EGAQSVPLDD GSWKYPDLQA SIPSVAKAMA LIHLSATHYH EHLCPALPLV TPKTFLDFLD
3130 3140 3150 3160 3170 3180
TFLMLQQQTI LKIKNKAQRV QNALENLRML IKEHGTHANL IFDLEQQLKD SGKSLSMFQQ
3190 3200 3210 3220 3230 3240
QLEQSKLLYK QQLEECRHQE NLIENLARQR DALQAQREAF LEQMSKAFLE PLSQLQVADF
3250 3260 3270 3280 3290 3300
EEIRSYRAPP ESVVRVTDAM CDLFHHETGW ASAKQLLCTE DFYQELVFFP KEKITDSELI
3310 3320 3330 3340 3350 3360
KLHLILKAPG MDDAALRAVS RPAASLAAWL WAVLHYGLAH CRGLPTDLLL QQVEATLTRE
3370 3380 3390 3400 3410 3420
QARLGYYQFQ AQETLEHNLA LAKMVEDAQA SHNCVAKTLS QAQCGQYHKW PMKAALLTPM
3430 3440 3450 3460 3470 3480
RAWTTQLQKL KGRCMTVFGD TLLCSAAIIY LGPFPPLRRQ ELLDEWLALC RGFQEALGPD
3490 3500 3510 3520 3530 3540
DVAQALKRKQ KSVSIPPKNP LLATHSPFSI LSLLSSESEQ YQWDGNLKPQ AKSAHLAGLL
3550 3560 3570 3580 3590 3600
LRSPTHYSSC RWPLLLDPSN EALIWLDPLP LEENRSFAPA LTEGRGKGLM RNQKRESKTD
3610 3620 3630 3640 3650 3660
MKEEDDESEE SNEAEDQTKE QKAEERKNEQ EKEQEENEEK EEEKTESQGS KPAYETQLPS
3670 3680 3690 3700 3710 3720
LPYLSVLSGA DPELGSQLQE AAACGLPVLL TNVELGLGCE ELQWLLQREQ LSPPQVQPGF
3730 3740 3750 3760 3770 3780
CLYLSTTLSL CAMEKVLGCE LLKGLNVLDL GLNMEILEEQ MLHEILCREY PELETRWQDL
3790 3800 3810 3820 3830 3840
KIRALDTCKA VEAAEERLLT MLLFQNPKRQ KPAKFLRNIV RAQGKLCQLR AHCEELEGQK
3850 3860 3870 3880 3890 3900
LQEMVLWAPY RPVVWHGMAM VKALSQLQNL LPLFCMSPEN WLAVTKQALD SMKPREINHG
3910 3920 3930 3940 3950 3960
EDLASHLLQL RAHLTRQLLG STVTALGLTQ VPLVGALGAL ALLQATGKAS ELERLALWPG
3970 3980 3990 4000 4010 4020
LAASPSTVHS KPVSDVARPA WLGPKAWHEC EMLELLPPFV GLCASLAGHS SAWQAYLSLS
4030 4040 4050 4060 4070 4080
STVLGPAPGP GPEPLSLLQK LILWRVLRPE CLAGALADFT TSLLGRPLDE NTYAPTMPFK
4090 4100 4110 4120 4130 4140
HSQATQPMLI LLPPPGHPSA TLHPLTVIQK LAAKYQQGQK QLQVIALGSE AWDPVSVVVS
4150 4160 4170 4180 4190 4200
TLSQAMYEGH WLVLDNCHLM PHWPKELLQL LLELLGRAKV VADLESEQLL DQPESRNVST
4210 4220 4230 4240 4250 4260
VHRDFRLWLI VPAESSASLP AVLTQHSMPV FWNQSLELGH VLIDSVELAQ QVLYMQPPTQ
4270 4280 4290 4300 4310 4320
ALPLLLLHGL LLHRQLYGTR LQAHRGRWSQ VTLTQVLQTQ DQLWASLSNP RAAMQELAAS
4330 4340 4350 4360 4370 4380
VFYGGPLGDT EDREALISLT QACLSPSSGS WVQPHTPQSL LATLMPLPEL RELDAMAECK
4390 4400 4410 4420 4430 4440
AQMHLLPSPP EPRLCGLSEG PQAWLLRRQS RALLSALQRS SPVWVPESRR GAQLAERRLR
4450 4460 4470 4480 4490 4500
QRLVQVNRRL ESLQDLLTHV IRQDESDAPW SVLGPNARRP LEGVLETEAL ELSQLVGTLQ
4510 4520 4530 4540 4550 4560
RDLDCLLQQL KGAPPCPSRR CAAVAHALWT GRLPLPWRPH APAGPQPPWH WLRQLSRRGQ
4570 4580 4590 4600 4610 4620
LLVRYLGVGA DASSDVPERV FHLSAFRHPR RLLLALRGEA ALDQNVPSSN FPGSRGSVSS
4630 4640 4650 4660 4670 4680
QLQYKRLEMN SNPLHFRVEN GPNPTVPERG LLLIGLQVLH AEWDPIAGAL QDSPSSQPSP
4690 4700 4710 4720 4730 4740
LPPVSISTQA PGTSDLPAPA DLTVYSCPVY MGGPLGTAKL QSRNIVMHLP LPTKLTPNTC
4750
VQRRVHVCSP PLS
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q96M86-1-unknown | MVPEER... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q96M86-1-unknown | MVPEER... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73039 | |||
| Q96M86-312-unknown | MVVPPD... | 312 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73040 | |||
| Q96M86-312-unknown | MVVPPD... | 312 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt100423 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...SPPLS | 4753 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|