Q96P47: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

General Information

Protein names	- Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 - AGAP-3 - CRAM-associated GTPase - CRAG - Centaurin-gamma-3 - Cnt-g3 - MR1-interacting protein - MRIP-1
Gene names	AGAP3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96P47

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 - Isoform 3 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 - Isoform 4 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 - Isoform 5 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 - Isoform 6 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

Sequence View

        10         20         30         40         50         60
MNFQAGGGQS PQQQQQLAGG PPQQFALSNS AAIRAEIQRF ESVHPNIYAI YDLIERIEDL
        70         80         90        100        110        120
ALQNQIREHV ISIEDSFVNS QEWTLSRSVP ELKVGIVGNL SSGKSALVHR YLTGTYVQEE
       130        140        150        160        170        180
SPEGGRFKKE IVVDGQSYLL LIRDEGGPPE LQFAAWVDAV VFVFSLEDEI SFQTVYNYFL
       190        200        210        220        230        240
RLCSFRNASE VPMVLVGTQD AISAANPRVI DDSRARKLST DLKRCTYYET CATYGLNVER
       250        260        270        280        290        300
VFQDVAQKVV ALRKKQQLAI GPCKSLPNSP SHSAVSAASI PAVHINQATN GGGSAFSDYS
       310        320        330        340        350        360
SSVPSTPSIS QRELRIETIA ASSTPTPIRK QSKRRSNIFT SRKGADLDRE KKAAECKVDS
       370        380        390        400        410        420
IGSGRAIPIK QGILLKRSGK SLNKEWKKKY VTLCDNGLLT YHPSLHDYMQ NIHGKEIDLL
       430        440        450        460        470        480
RTTVKVPGKR LPRATPATAP GTSPRANGLS VERSNTQLGG GTGAPHSASS ASLHSERPLS
       490        500        510        520        530        540
SSAWAGPRPE GLHQRSCSVS SADQWSEATT SLPPGMQHPA SGPAEVLSSS PKLDPPPSPH
       550        560        570        580        590        600
SNRKKHRRKK STGTPRPDGP SSATEEAEES FEFVVVSLTG QTWHFEASTA EERELWVQSV
       610        620        630        640        650        660
QAQILASLQG CRSAKDKTRL GNQNAALAVQ AVRTVRGNSF CIDCDAPNPD WASLNLGALM
       670        680        690        700        710        720
CIECSGIHRH LGAHLSRVRS LDLDDWPPEL LAVMTAMGNA LANSVWEGAL GGYSKPGPDA
       730        740        750        760        770        780
CREEKERWIR AKYEQKLFLA PLPSSDVPLG QQLLRAVVED DLRLLVMLLA HGSKEEVNET
       790        800        810        820        830        840
YGDGDGRTAL HLSSAMANVV FTQLLIWYGV DVRSRDARGL TPLAYARRAG SQECADILIQ
       850        860        870
HGCPGEGCGL APTPNREPAN GTNPSAELHR SPSLL         10         20         30         40         50         60
MNFQAGGGQS PQQQQQLAGG PPQQFALSNS AAIRAEIQRF ESVHPNIYAI YDLIERIEDL
        70         80         90        100        110        120
ALQNQIREHV ISIEDSFVNS QEWTLSRSVP ELKVGIVGNL SSGKSALVHR YLTGTYVQEE
       130        140        150        160        170        180
SPEGGRFKKE IVVDGQSYLL LIRDEGGPPE LQFAAWVDAV VFVFSLEDEI SFQTVYNYFL
       190        200        210        220        230        240
RLCSFRNASE VPMVLVGTQD AISAANPRVI DDSRARKLST DLKRCTYYET CATYGLNVER
       250        260        270        280        290        300
VFQDVAQKVV ALRKKQQLAI GPCKSLPNSP SHSAVSAASI PAVHINQATN GGGSAFSDYS
       310        320        330        340        350        360
SSVPSTPSIS QRELRIETIA ASSTPTPIRK QSKRRSNIFT SRKGADLDRE KKAAECKVDS
       370        380        390        400        410        420
IGSGRAIPIK QGILLKRSGK SLNKEWKKKY VTLCDNGLLT YHPSLHDYMQ NIHGKEIDLL
       430        440        450        460        470        480
RTTVKVPGKR LPRATPATAP GTSPRANGLS VERSNTQLGG GTGAPHSASS ASLHSERPLS
       490        500        510        520        530        540
SSAWAGPRPE GLHQRSCSVS SADQWSEATT SLPPGMQHPA SGPAEVLSSS PKLDPPPSPH
       550        560        570        580        590        600
SNRKKHRRKK STGTPRPDGP SSATEEAEES FEFVVVSLTG QTWHFEASTA EERELWVQSV
       610        620        630        640        650        660
QAQILASLQG CRSAKDKTRL GNQNAALAVQ AVRTVRGNSF CIDCDAPNPD WASLNLGALM
       670        680        690        700        710        720
CIECSGIHRH LGAHLSRVRS LDLDDWPPEL LAVMTAMGNA LANSVWEGAL GGYSKPGPDA
       730        740        750        760        770        780
CREEKERWIR AKYEQKLFLA PLPSSDVPLG QQLLRAVVED DLRLLVMLLA HGSKEEVNET
       790        800        810        820        830        840
YGDGDGRTAL HLSSAMANVV FTQLLIWYGV DVRSRDARGL TPLAYARRAG SQECADILIQ
       850        860        870
HGCPGEGCGL APTPNREPAN GTNPSAELHR SPSLL         10         20         30         40         50         60
MNFQAGGGQS PQQQQQLAGG PPQQFALSNS AAIRAEIQRF ESVHPNIYAI YDLIERIEDL
        70         80         90        100        110        120
ALQNQIREHV ISIEDSFVNS QEWTLSRSVP ELKVGIVGNL SSGKSALVHR YLTGTYVQEE
       130        140        150        160        170        180
SPEGGRFKKE IVVDGQSYLL LIRDEGGPPE LQFAAWVDAV VFVFSLEDEI SFQTVYNYFL
       190        200        210        220        230        240
RLCSFRNASE VPMVLVGTQD AISAANPRVI DDSRARKLST DLKRCTYYET CATYGLNVER
       250        260        270        280        290        300
VFQDVAQKVV ALRKKQQLAI GPCKSLPNSP SHSAVSAASI PAVHINQATN GGGSAFSDYS
       310        320        330        340        350        360
SSVPSTPSIS QRELRIETIA ASSTPTPIRK QSKRRSNIFT SRKGADLDRE KKAAECKVDS
       370        380        390        400        410        420
IGSGRAIPIK QGILLKRSGK SLNKEWKKKY VTLCDNGLLT YHPSLHDYMQ NIHGKEIDLL
       430        440        450        460        470        480
RTTVKVPGKR LPRATPATAP GTSPRANGLS VERSNTQLGG GTGAPHSASS ASLHSERPLS
       490        500        510        520        530        540
SSAWAGPRPE GLHQRSCSVS SADQWSEATT SLPPGMQHPA SGPAEVLSSS PKLDPPPSPH
       550        560        570        580        590        600
SNRKKHRRKK STGTPRPDGP SSATEEAEES FEFVVVSLTG QTWHFEASTA EERELWVQSV
       610        620        630        640        650        660
QAQILASLQG CRSAKDKTRL GNQNAALAVQ AVRTVRGNSF CIDCDAPNPD WASLNLGALM
       670        680        690        700        710        720
CIECSGIHRH LGAHLSRVRS LDLDDWPPEL LAVMTAMGNA LANSVWEGAL GGYSKPGPDA
       730        740        750        760        770        780
CREEKERWIR AKYEQKLFLA PLPSSDVPLG QQLLRAVVED DLRLLVMLLA HGSKEEVNET
       790        800        810        820        830        840
YGDGDGRTAL HLSSAMANVV FTQLLIWYGV DVRSRDARGL TPLAYARRAG SQECADILIQ
       850        860        870
HGCPGEGCGL APTPNREPAN GTNPSAELHR SPSLL         10         20         30         40         50         60
MNFQAGGGQS PQQQQQLAGG PPQQFALSNS AAIRAEIQRF ESVHPNIYAI YDLIERIEDL
        70         80         90        100        110        120
ALQNQIREHV ISIEDSFVNS QEWTLSRSVP ELKVGIVGNL SSGKSALVHR YLTGTYVQEE
       130        140        150        160        170        180
SPEGGRFKKE IVVDGQSYLL LIRDEGGPPE LQFAAWVDAV VFVFSLEDEI SFQTVYNYFL
       190        200        210        220        230        240
RLCSFRNASE VPMVLVGTQD AISAANPRVI DDSRARKLST DLKRCTYYET CATYGLNVER
       250        260        270        280        290        300
VFQDVAQKVV ALRKKQQLAI GPCKSLPNSP SHSAVSAASI PAVHINQATN GGGSAFSDYS
       310        320        330        340        350        360
SSVPSTPSIS QRELRIETIA ASSTPTPIRK QSKRRSNIFT SRKGADLDRE KKAAECKVDS
       370        380        390        400        410        420
IGSGRAIPIK QGILLKRSGK SLNKEWKKKY VTLCDNGLLT YHPSLHDYMQ NIHGKEIDLL
       430        440        450        460        470        480
RTTVKVPGKR LPRATPATAP GTSPRANGLS VERSNTQLGG GTGAPHSASS ASLHSERPLS
       490        500        510        520        530        540
SSAWAGPRPE GLHQRSCSVS SADQWSEATT SLPPGMQHPA SGPAEVLSSS PKLDPPPSPH
       550        560        570        580        590        600
SNRKKHRRKK STGTPRPDGP SSATEEAEES FEFVVVSLTG QTWHFEASTA EERELWVQSV
       610        620        630        640        650        660
QAQILASLQG CRSAKDKTRL GNQNAALAVQ AVRTVRGNSF CIDCDAPNPD WASLNLGALM
       670        680        690        700        710        720
CIECSGIHRH LGAHLSRVRS LDLDDWPPEL LAVMTAMGNA LANSVWEGAL GGYSKPGPDA
       730        740        750        760        770        780
CREEKERWIR AKYEQKLFLA PLPSSDVPLG QQLLRAVVED DLRLLVMLLA HGSKEEVNET
       790        800        810        820        830        840
YGDGDGRTAL HLSSAMANVV FTQLLIWYGV DVRSRDARGL TPLAYARRAG SQECADILIQ
       850        860        870
HGCPGEGCGL APTPNREPAN GTNPSAELHR SPSLL         10         20         30         40         50         60
MNFQAGGGQS PQQQQQLAGG PPQQFALSNS AAIRAEIQRF ESVHPNIYAI YDLIERIEDL
        70         80         90        100        110        120
ALQNQIREHV ISIEDSFVNS QEWTLSRSVP ELKVGIVGNL SSGKSALVHR YLTGTYVQEE
       130        140        150        160        170        180
SPEGGRFKKE IVVDGQSYLL LIRDEGGPPE LQFAAWVDAV VFVFSLEDEI SFQTVYNYFL
       190        200        210        220        230        240
RLCSFRNASE VPMVLVGTQD AISAANPRVI DDSRARKLST DLKRCTYYET CATYGLNVER
       250        260        270        280        290        300
VFQDVAQKVV ALRKKQQLAI GPCKSLPNSP SHSAVSAASI PAVHINQATN GGGSAFSDYS
       310        320        330        340        350        360
SSVPSTPSIS QRELRIETIA ASSTPTPIRK QSKRRSNIFT SRKGADLDRE KKAAECKVDS
       370        380        390        400        410        420
IGSGRAIPIK QGILLKRSGK SLNKEWKKKY VTLCDNGLLT YHPSLHDYMQ NIHGKEIDLL
       430        440        450        460        470        480
RTTVKVPGKR LPRATPATAP GTSPRANGLS VERSNTQLGG GTGAPHSASS ASLHSERPLS
       490        500        510        520        530        540
SSAWAGPRPE GLHQRSCSVS SADQWSEATT SLPPGMQHPA SGPAEVLSSS PKLDPPPSPH
       550        560        570        580        590        600
SNRKKHRRKK STGTPRPDGP SSATEEAEES FEFVVVSLTG QTWHFEASTA EERELWVQSV
       610        620        630        640        650        660
QAQILASLQG CRSAKDKTRL GNQNAALAVQ AVRTVRGNSF CIDCDAPNPD WASLNLGALM
       670        680        690        700        710        720
CIECSGIHRH LGAHLSRVRS LDLDDWPPEL LAVMTAMGNA LANSVWEGAL GGYSKPGPDA
       730        740        750        760        770        780
CREEKERWIR AKYEQKLFLA PLPSSDVPLG QQLLRAVVED DLRLLVMLLA HGSKEEVNET
       790        800        810        820        830        840
YGDGDGRTAL HLSSAMANVV FTQLLIWYGV DVRSRDARGL TPLAYARRAG SQECADILIQ
       850        860        870
HGCPGEGCGL APTPNREPAN GTNPSAELHR SPSLL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q96P47-1-unknown	MNFQAG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96P47-1-unknown	MNFQAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66489
Q96P47-193-unknown	MVLVGT...	193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66491
Q96P47-193-unknown	MVLVGT...	193	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418016
Q96P47-193-unknown	MVLVGT...	193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106334
Q96P47-193-unknown	MVLVGT...	193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106335
Q96P47-193-unknown	MVLVGT...	193	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106333
Q96P47-200-unknown	DAISAA...	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418159
Q96P47-200-unknown	DAISAA...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198050
Q96P47-200-unknown	DAISAA...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198052
Q96P47-200-unknown	DAISAA...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198053
Q96P47-200-unknown	DAISAA...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198051

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LSTDLK	222	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417151
...SPSLL	875	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SPSLL	875	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62109
...SPSLL	875	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62106
...SPSLL	875	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt62108

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)