TopFIND 4.0

Q96Q40: Cyclin-dependent kinase 15

General Information

Protein names
- Cyclin-dependent kinase 15
- 2.7.11.22 {ECO:0000269|PubMed:24866247}
- Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein
- Cell division protein kinase 15
- Serine/threonine-protein kinase ALS2CR7
- Serine/threonine-protein kinase PFTAIRE-2
Gene names CDK15
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96Q40

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW

Isoforms

- Isoform 2 of Cyclin-dependent kinase 15 - Isoform 3 of Cyclin-dependent kinase 15 - Isoform 4 of Cyclin-dependent kinase 15 - Isoform 5 of Cyclin-dependent kinase 15 - Isoform 6 of Cyclin-dependent kinase 15

Sequence View

        10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW         10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW         10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW         10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW         10         20         30         40         50         60 
MGQELCAKTV QPGCSCYHCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 
        70         80         90        100        110        120 
QAARAQKFKS KRPRSNSDCF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 
       130        140        150        160        170        180 
ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 
       190        200        210        220        230        240 
MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 
       250        260        270        280        290        300 
ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 
       310        320        330        340        350        360 
PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WNRLGRVPEA 
       370        380        390        400        410        420 
EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 
       430    
SYQKGHHPAQ FSKCW



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)