TopFIND 4.0

Q96RD7: Pannexin-1

General Information

Protein names
- Pannexin-1
Gene names PANX1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96RD7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAIAQLATEY VFSDFLLKEP TEPKFKGLRL ELAVDKMVTC IAVGLPLLLI SLAFAQEISI 
        70         80         90        100        110        120 
GTQISCFSPS SFSWRQAAFV DSYCWAAVQQ KNSLQSESGN LPLWLHKFFP YILLLFAILL 
       130        140        150        160        170        180 
YLPPLFWRFA AAPHICSDLK FIMEELDKVY NRAIKAAKSA RDLDMRDGAC SVPGVTENLG 
       190        200        210        220        230        240 
QSLWEVSESH FKYPIVEQYL KTKKNSNNLI IKYISCRLLT LIIILLACIY LGYYFSLSSL 
       250        260        270        280        290        300 
SDEFVCSIKS GILRNDSTVP DQFQCKLIAV GIFQLLSVIN LVVYVLLAPV VVYTLFVPFR 
       310        320        330        340        350        360 
QKTDVLKVYE ILPTFDVLHF KSEGYNDLSL YNLFLEENIS EVKSYKCLKV LENIKSSGQG 
       370        380        390        400        410        420 
IDPMLLLTNL GMIKMDVVDG KTPMSAEMRE EQGNQTAELQ GMNIDSETKA NNGEKNARQR 
   
LLDSSC

Isoforms

- Isoform 2 of Pannexin-1

Sequence View

        10         20         30         40         50         60 
MAIAQLATEY VFSDFLLKEP TEPKFKGLRL ELAVDKMVTC IAVGLPLLLI SLAFAQEISI 
        70         80         90        100        110        120 
GTQISCFSPS SFSWRQAAFV DSYCWAAVQQ KNSLQSESGN LPLWLHKFFP YILLLFAILL 
       130        140        150        160        170        180 
YLPPLFWRFA AAPHICSDLK FIMEELDKVY NRAIKAAKSA RDLDMRDGAC SVPGVTENLG 
       190        200        210        220        230        240 
QSLWEVSESH FKYPIVEQYL KTKKNSNNLI IKYISCRLLT LIIILLACIY LGYYFSLSSL 
       250        260        270        280        290        300 
SDEFVCSIKS GILRNDSTVP DQFQCKLIAV GIFQLLSVIN LVVYVLLAPV VVYTLFVPFR 
       310        320        330        340        350        360 
QKTDVLKVYE ILPTFDVLHF KSEGYNDLSL YNLFLEENIS EVKSYKCLKV LENIKSSGQG 
       370        380        390        400        410        420 
IDPMLLLTNL GMIKMDVVDG KTPMSAEMRE EQGNQTAELQ GMNIDSETKA NNGEKNARQR 
   
LLDSSC



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96RD7-1-unknown MAIAQL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96RD7-1-unknown MAIAQL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt84221

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LDSSC 426 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LDSSC 426 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79839

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)