Q96S94: Cyclin-L2

General Information

Protein names	- Cyclin-L2 - Paneth cell-enhanced expression protein
Gene names	CCNL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96S94

7 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cyclin-L2 - Isoform 3 of Cyclin-L2 - Isoform 2 of Cyclin-L2 - Isoform 4 of Cyclin-L2 - Isoform 5 of Cyclin-L2

Sequence View

        10         20         30         40         50         60
MAAAAAAAGA AGSAAPAAAA GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR
        70         80         90        100        110        120
FTPSMSSGLD TDTETDLRVV GCELIQAAGI LLRLPQVAMA TGQVLFQRFF YTKSFVKHSM
       130        140        150        160        170        180
EHVSMACVHL ASKIEEAPRR IRDVINVFHR LRQLRDKKKP VPLLLDQDYV NLKNQIIKAE
       190        200        210        220        230        240
RRVLKELGFC VHVKHPHKII VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI
       250        260        270        280        290        300
ACACIYLAAR TLEIPLPNRP HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK
       310        320        330        340        350        360
RKHAIEEAKA QARGLLPGGT QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRLE
       370        380        390        400        410        420
GAKKAKADSP VNGLPKGRES RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR
       430        440        450        460        470        480
SRSRSDSPPR QAPRSAPYKG SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERADNP
       490        500        510        520
GKYKKKSHYY RDQRRERSRS YERTGRRYER DHPGHSRHRR         10         20         30         40         50         60
MAAAAAAAGA AGSAAPAAAA GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR
        70         80         90        100        110        120
FTPSMSSGLD TDTETDLRVV GCELIQAAGI LLRLPQVAMA TGQVLFQRFF YTKSFVKHSM
       130        140        150        160        170        180
EHVSMACVHL ASKIEEAPRR IRDVINVFHR LRQLRDKKKP VPLLLDQDYV NLKNQIIKAE
       190        200        210        220        230        240
RRVLKELGFC VHVKHPHKII VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI
       250        260        270        280        290        300
ACACIYLAAR TLEIPLPNRP HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK
       310        320        330        340        350        360
RKHAIEEAKA QARGLLPGGT QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRLE
       370        380        390        400        410        420
GAKKAKADSP VNGLPKGRES RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR
       430        440        450        460        470        480
SRSRSDSPPR QAPRSAPYKG SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERADNP
       490        500        510        520
GKYKKKSHYY RDQRRERSRS YERTGRRYER DHPGHSRHRR         10         20         30         40         50         60
MAAAAAAAGA AGSAAPAAAA GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR
        70         80         90        100        110        120
FTPSMSSGLD TDTETDLRVV GCELIQAAGI LLRLPQVAMA TGQVLFQRFF YTKSFVKHSM
       130        140        150        160        170        180
EHVSMACVHL ASKIEEAPRR IRDVINVFHR LRQLRDKKKP VPLLLDQDYV NLKNQIIKAE
       190        200        210        220        230        240
RRVLKELGFC VHVKHPHKII VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI
       250        260        270        280        290        300
ACACIYLAAR TLEIPLPNRP HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK
       310        320        330        340        350        360
RKHAIEEAKA QARGLLPGGT QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRLE
       370        380        390        400        410        420
GAKKAKADSP VNGLPKGRES RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR
       430        440        450        460        470        480
SRSRSDSPPR QAPRSAPYKG SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERADNP
       490        500        510        520
GKYKKKSHYY RDQRRERSRS YERTGRRYER DHPGHSRHRR         10         20         30         40         50         60
MAAAAAAAGA AGSAAPAAAA GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR
        70         80         90        100        110        120
FTPSMSSGLD TDTETDLRVV GCELIQAAGI LLRLPQVAMA TGQVLFQRFF YTKSFVKHSM
       130        140        150        160        170        180
EHVSMACVHL ASKIEEAPRR IRDVINVFHR LRQLRDKKKP VPLLLDQDYV NLKNQIIKAE
       190        200        210        220        230        240
RRVLKELGFC VHVKHPHKII VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI
       250        260        270        280        290        300
ACACIYLAAR TLEIPLPNRP HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK
       310        320        330        340        350        360
RKHAIEEAKA QARGLLPGGT QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRLE
       370        380        390        400        410        420
GAKKAKADSP VNGLPKGRES RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR
       430        440        450        460        470        480
SRSRSDSPPR QAPRSAPYKG SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERADNP
       490        500        510        520
GKYKKKSHYY RDQRRERSRS YERTGRRYER DHPGHSRHRR         10         20         30         40         50         60
MAAAAAAAGA AGSAAPAAAA GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR
        70         80         90        100        110        120
FTPSMSSGLD TDTETDLRVV GCELIQAAGI LLRLPQVAMA TGQVLFQRFF YTKSFVKHSM
       130        140        150        160        170        180
EHVSMACVHL ASKIEEAPRR IRDVINVFHR LRQLRDKKKP VPLLLDQDYV NLKNQIIKAE
       190        200        210        220        230        240
RRVLKELGFC VHVKHPHKII VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI
       250        260        270        280        290        300
ACACIYLAAR TLEIPLPNRP HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK
       310        320        330        340        350        360
RKHAIEEAKA QARGLLPGGT QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRLE
       370        380        390        400        410        420
GAKKAKADSP VNGLPKGRES RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR
       430        440        450        460        470        480
SRSRSDSPPR QAPRSAPYKG SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERADNP
       490        500        510        520
GKYKKKSHYY RDQRRERSRS YERTGRRYER DHPGHSRHRR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96S94-2-unknown	MAAAAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96S94-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69788
Q96S94-2-Acetylation	AAAAAA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96S94-2-Acetylation	AAAAAA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96S94-2-Acetylation	AAAAAA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q96S94-2-Acetylation	AAAAAA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96S94-2-Acetylation	AAAAAA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110285
Q96S94-99-unknown	MATGQV...	99		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000464685
Q96S94-99-unknown	MATGQV...	99		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt196946
Q96S94-223-unknown	MNDSLR...	223		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69789
Q96S94-223-unknown	MNDSLR...	223		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000386132
Q96S94-325-	GTSGFS...	325			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96S94-325-unknown	GTSGFS...	325		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176000

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AERRVL	183	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464685
...AERRVL	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155434
...SRHRR	520	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SRHRR	520	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65407

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)