Q96T76: MMS19 nucleotide excision repair protein homolog

General Information

Protein names	- MMS19 nucleotide excision repair protein homolog - hMMS19 - MET18 homolog - MMS19-like protein
Gene names	MMS19
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96T76

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of MMS19 nucleotide excision repair protein homolog - Isoform 3 of MMS19 nucleotide excision repair protein homolog - Isoform 4 of MMS19 nucleotide excision repair protein homolog - Isoform 5 of MMS19 nucleotide excision repair protein homolog - Isoform 6 of MMS19 nucleotide excision repair protein homolog

Sequence View

        10         20         30         40         50         60
MAAAAAVEAA APMGALWGLV HDFVVGQQEG PADQVAADVK SGNYTVLQVV EALGSSLENP
        70         80         90        100        110        120
EPRTRARAIQ LLSQVLLHCH TLLLEKEVVH LILFYENRLK DHHLVIPSVL QGLKALSLCV
       130        140        150        160        170        180
ALPPGLAVSV LKAIFQEVHV QSLPQVDRHT VYNIITNFMR TREEELKSLG ADFTFGFIQV
       190        200        210        220        230        240
MDGEKDPRNL LVAFRIVHDL ISRDYSLGPF VEELFEVTSC YFPIDFTPPP NDPHGIQRED
       250        260        270        280        290        300
LILSLRAVLA STPRFAEFLL PLLIEKVDSE VLSAKLDSLQ TLNACCAVYG QKELKDFLPS
       310        320        330        340        350        360
LWASIRREVF QTASERVEAE GLAALHSLTA CLSRSVLRAD AEDLLDSFLS NILQDCRHHL
       370        380        390        400        410        420
CEPDMKLVWP SAKLLQAAAG ASARACDSVT SNVLPLLLEQ FHKHSQSSQR RTILEMLLGF
       430        440        450        460        470        480
LKLQQKWSYE DKDQRPLNGF KDQLCSLVFM ALTDPSTQLQ LVGIRTLTVL GAQPDLLSYE
       490        500        510        520        530        540
DLELAVGHLY RLSFLKEDSQ SCRVAALEAS GTLAALYPVA FSSHLVPKLA EELRVGESNL
       550        560        570        580        590        600
TNGDEPTQCS RHLCCLQALS AVSTHPSIVK ETLPLLLQHL WQVNRGNMVA QSSDVIAVCQ
       610        620        630        640        650        660
SLRQMAEKCQ QDPESCWYFH QTAIPCLLAL AVQASMPEKE PSVLRKVLLE DEVLAAMVSV
       670        680        690        700        710        720
IGTATTHLSP ELAAQSVTHI VPLFLDGNVS FLPENSFPSR FQPFQDGSSG QRRLIALLMA
       730        740        750        760        770        780
FVCSLPRNVE IPQLNQLMRE LLELSCCHSC PFSSTAAAKC FAGLLNKHPA GQQLDEFLQL
       790        800        810        820        830        840
AVDKVEAGLG SGPCRSQAFT LLLWVTKALV LRYHPLSSCL TARLMGLLSD PELGPAAADG
       850        860        870        880        890        900
FSLLMSDCTD VLTRAGHAEV RIMFRQRFFT DNVPALVQGF HAAPQDVKPN YLKGLSHVLN
       910        920        930        940        950        960
RLPKPVLLPE LPTLLSLLLE ALSCPDCVVQ LSTLSCLQPL LLEAPQVMSL HVDTLVTKFL
       970        980        990       1000       1010       1020
NLSSSPSMAV RIAALQCMHA LTRLPTPVLL PYKPQVIRAL AKPLDDKKRL VRKEAVSARG
      1030
EWFLLGSPGS         10         20         30         40         50         60
MAAAAAVEAA APMGALWGLV HDFVVGQQEG PADQVAADVK SGNYTVLQVV EALGSSLENP
        70         80         90        100        110        120
EPRTRARAIQ LLSQVLLHCH TLLLEKEVVH LILFYENRLK DHHLVIPSVL QGLKALSLCV
       130        140        150        160        170        180
ALPPGLAVSV LKAIFQEVHV QSLPQVDRHT VYNIITNFMR TREEELKSLG ADFTFGFIQV
       190        200        210        220        230        240
MDGEKDPRNL LVAFRIVHDL ISRDYSLGPF VEELFEVTSC YFPIDFTPPP NDPHGIQRED
       250        260        270        280        290        300
LILSLRAVLA STPRFAEFLL PLLIEKVDSE VLSAKLDSLQ TLNACCAVYG QKELKDFLPS
       310        320        330        340        350        360
LWASIRREVF QTASERVEAE GLAALHSLTA CLSRSVLRAD AEDLLDSFLS NILQDCRHHL
       370        380        390        400        410        420
CEPDMKLVWP SAKLLQAAAG ASARACDSVT SNVLPLLLEQ FHKHSQSSQR RTILEMLLGF
       430        440        450        460        470        480
LKLQQKWSYE DKDQRPLNGF KDQLCSLVFM ALTDPSTQLQ LVGIRTLTVL GAQPDLLSYE
       490        500        510        520        530        540
DLELAVGHLY RLSFLKEDSQ SCRVAALEAS GTLAALYPVA FSSHLVPKLA EELRVGESNL
       550        560        570        580        590        600
TNGDEPTQCS RHLCCLQALS AVSTHPSIVK ETLPLLLQHL WQVNRGNMVA QSSDVIAVCQ
       610        620        630        640        650        660
SLRQMAEKCQ QDPESCWYFH QTAIPCLLAL AVQASMPEKE PSVLRKVLLE DEVLAAMVSV
       670        680        690        700        710        720
IGTATTHLSP ELAAQSVTHI VPLFLDGNVS FLPENSFPSR FQPFQDGSSG QRRLIALLMA
       730        740        750        760        770        780
FVCSLPRNVE IPQLNQLMRE LLELSCCHSC PFSSTAAAKC FAGLLNKHPA GQQLDEFLQL
       790        800        810        820        830        840
AVDKVEAGLG SGPCRSQAFT LLLWVTKALV LRYHPLSSCL TARLMGLLSD PELGPAAADG
       850        860        870        880        890        900
FSLLMSDCTD VLTRAGHAEV RIMFRQRFFT DNVPALVQGF HAAPQDVKPN YLKGLSHVLN
       910        920        930        940        950        960
RLPKPVLLPE LPTLLSLLLE ALSCPDCVVQ LSTLSCLQPL LLEAPQVMSL HVDTLVTKFL
       970        980        990       1000       1010       1020
NLSSSPSMAV RIAALQCMHA LTRLPTPVLL PYKPQVIRAL AKPLDDKKRL VRKEAVSARG
      1030
EWFLLGSPGS         10         20         30         40         50         60
MAAAAAVEAA APMGALWGLV HDFVVGQQEG PADQVAADVK SGNYTVLQVV EALGSSLENP
        70         80         90        100        110        120
EPRTRARAIQ LLSQVLLHCH TLLLEKEVVH LILFYENRLK DHHLVIPSVL QGLKALSLCV
       130        140        150        160        170        180
ALPPGLAVSV LKAIFQEVHV QSLPQVDRHT VYNIITNFMR TREEELKSLG ADFTFGFIQV
       190        200        210        220        230        240
MDGEKDPRNL LVAFRIVHDL ISRDYSLGPF VEELFEVTSC YFPIDFTPPP NDPHGIQRED
       250        260        270        280        290        300
LILSLRAVLA STPRFAEFLL PLLIEKVDSE VLSAKLDSLQ TLNACCAVYG QKELKDFLPS
       310        320        330        340        350        360
LWASIRREVF QTASERVEAE GLAALHSLTA CLSRSVLRAD AEDLLDSFLS NILQDCRHHL
       370        380        390        400        410        420
CEPDMKLVWP SAKLLQAAAG ASARACDSVT SNVLPLLLEQ FHKHSQSSQR RTILEMLLGF
       430        440        450        460        470        480
LKLQQKWSYE DKDQRPLNGF KDQLCSLVFM ALTDPSTQLQ LVGIRTLTVL GAQPDLLSYE
       490        500        510        520        530        540
DLELAVGHLY RLSFLKEDSQ SCRVAALEAS GTLAALYPVA FSSHLVPKLA EELRVGESNL
       550        560        570        580        590        600
TNGDEPTQCS RHLCCLQALS AVSTHPSIVK ETLPLLLQHL WQVNRGNMVA QSSDVIAVCQ
       610        620        630        640        650        660
SLRQMAEKCQ QDPESCWYFH QTAIPCLLAL AVQASMPEKE PSVLRKVLLE DEVLAAMVSV
       670        680        690        700        710        720
IGTATTHLSP ELAAQSVTHI VPLFLDGNVS FLPENSFPSR FQPFQDGSSG QRRLIALLMA
       730        740        750        760        770        780
FVCSLPRNVE IPQLNQLMRE LLELSCCHSC PFSSTAAAKC FAGLLNKHPA GQQLDEFLQL
       790        800        810        820        830        840
AVDKVEAGLG SGPCRSQAFT LLLWVTKALV LRYHPLSSCL TARLMGLLSD PELGPAAADG
       850        860        870        880        890        900
FSLLMSDCTD VLTRAGHAEV RIMFRQRFFT DNVPALVQGF HAAPQDVKPN YLKGLSHVLN
       910        920        930        940        950        960
RLPKPVLLPE LPTLLSLLLE ALSCPDCVVQ LSTLSCLQPL LLEAPQVMSL HVDTLVTKFL
       970        980        990       1000       1010       1020
NLSSSPSMAV RIAALQCMHA LTRLPTPVLL PYKPQVIRAL AKPLDDKKRL VRKEAVSARG
      1030
EWFLLGSPGS         10         20         30         40         50         60
MAAAAAVEAA APMGALWGLV HDFVVGQQEG PADQVAADVK SGNYTVLQVV EALGSSLENP
        70         80         90        100        110        120
EPRTRARAIQ LLSQVLLHCH TLLLEKEVVH LILFYENRLK DHHLVIPSVL QGLKALSLCV
       130        140        150        160        170        180
ALPPGLAVSV LKAIFQEVHV QSLPQVDRHT VYNIITNFMR TREEELKSLG ADFTFGFIQV
       190        200        210        220        230        240
MDGEKDPRNL LVAFRIVHDL ISRDYSLGPF VEELFEVTSC YFPIDFTPPP NDPHGIQRED
       250        260        270        280        290        300
LILSLRAVLA STPRFAEFLL PLLIEKVDSE VLSAKLDSLQ TLNACCAVYG QKELKDFLPS
       310        320        330        340        350        360
LWASIRREVF QTASERVEAE GLAALHSLTA CLSRSVLRAD AEDLLDSFLS NILQDCRHHL
       370        380        390        400        410        420
CEPDMKLVWP SAKLLQAAAG ASARACDSVT SNVLPLLLEQ FHKHSQSSQR RTILEMLLGF
       430        440        450        460        470        480
LKLQQKWSYE DKDQRPLNGF KDQLCSLVFM ALTDPSTQLQ LVGIRTLTVL GAQPDLLSYE
       490        500        510        520        530        540
DLELAVGHLY RLSFLKEDSQ SCRVAALEAS GTLAALYPVA FSSHLVPKLA EELRVGESNL
       550        560        570        580        590        600
TNGDEPTQCS RHLCCLQALS AVSTHPSIVK ETLPLLLQHL WQVNRGNMVA QSSDVIAVCQ
       610        620        630        640        650        660
SLRQMAEKCQ QDPESCWYFH QTAIPCLLAL AVQASMPEKE PSVLRKVLLE DEVLAAMVSV
       670        680        690        700        710        720
IGTATTHLSP ELAAQSVTHI VPLFLDGNVS FLPENSFPSR FQPFQDGSSG QRRLIALLMA
       730        740        750        760        770        780
FVCSLPRNVE IPQLNQLMRE LLELSCCHSC PFSSTAAAKC FAGLLNKHPA GQQLDEFLQL
       790        800        810        820        830        840
AVDKVEAGLG SGPCRSQAFT LLLWVTKALV LRYHPLSSCL TARLMGLLSD PELGPAAADG
       850        860        870        880        890        900
FSLLMSDCTD VLTRAGHAEV RIMFRQRFFT DNVPALVQGF HAAPQDVKPN YLKGLSHVLN
       910        920        930        940        950        960
RLPKPVLLPE LPTLLSLLLE ALSCPDCVVQ LSTLSCLQPL LLEAPQVMSL HVDTLVTKFL
       970        980        990       1000       1010       1020
NLSSSPSMAV RIAALQCMHA LTRLPTPVLL PYKPQVIRAL AKPLDDKKRL VRKEAVSARG
      1030
EWFLLGSPGS         10         20         30         40         50         60
MAAAAAVEAA APMGALWGLV HDFVVGQQEG PADQVAADVK SGNYTVLQVV EALGSSLENP
        70         80         90        100        110        120
EPRTRARAIQ LLSQVLLHCH TLLLEKEVVH LILFYENRLK DHHLVIPSVL QGLKALSLCV
       130        140        150        160        170        180
ALPPGLAVSV LKAIFQEVHV QSLPQVDRHT VYNIITNFMR TREEELKSLG ADFTFGFIQV
       190        200        210        220        230        240
MDGEKDPRNL LVAFRIVHDL ISRDYSLGPF VEELFEVTSC YFPIDFTPPP NDPHGIQRED
       250        260        270        280        290        300
LILSLRAVLA STPRFAEFLL PLLIEKVDSE VLSAKLDSLQ TLNACCAVYG QKELKDFLPS
       310        320        330        340        350        360
LWASIRREVF QTASERVEAE GLAALHSLTA CLSRSVLRAD AEDLLDSFLS NILQDCRHHL
       370        380        390        400        410        420
CEPDMKLVWP SAKLLQAAAG ASARACDSVT SNVLPLLLEQ FHKHSQSSQR RTILEMLLGF
       430        440        450        460        470        480
LKLQQKWSYE DKDQRPLNGF KDQLCSLVFM ALTDPSTQLQ LVGIRTLTVL GAQPDLLSYE
       490        500        510        520        530        540
DLELAVGHLY RLSFLKEDSQ SCRVAALEAS GTLAALYPVA FSSHLVPKLA EELRVGESNL
       550        560        570        580        590        600
TNGDEPTQCS RHLCCLQALS AVSTHPSIVK ETLPLLLQHL WQVNRGNMVA QSSDVIAVCQ
       610        620        630        640        650        660
SLRQMAEKCQ QDPESCWYFH QTAIPCLLAL AVQASMPEKE PSVLRKVLLE DEVLAAMVSV
       670        680        690        700        710        720
IGTATTHLSP ELAAQSVTHI VPLFLDGNVS FLPENSFPSR FQPFQDGSSG QRRLIALLMA
       730        740        750        760        770        780
FVCSLPRNVE IPQLNQLMRE LLELSCCHSC PFSSTAAAKC FAGLLNKHPA GQQLDEFLQL
       790        800        810        820        830        840
AVDKVEAGLG SGPCRSQAFT LLLWVTKALV LRYHPLSSCL TARLMGLLSD PELGPAAADG
       850        860        870        880        890        900
FSLLMSDCTD VLTRAGHAEV RIMFRQRFFT DNVPALVQGF HAAPQDVKPN YLKGLSHVLN
       910        920        930        940        950        960
RLPKPVLLPE LPTLLSLLLE ALSCPDCVVQ LSTLSCLQPL LLEAPQVMSL HVDTLVTKFL
       970        980        990       1000       1010       1020
NLSSSPSMAV RIAALQCMHA LTRLPTPVLL PYKPQVIRAL AKPLDDKKRL VRKEAVSARG
      1030
EWFLLGSPGS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q96T76-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81301
Q96T76-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81302
Q96T76-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81303
Q96T76-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81305
Q96T76-1-unknown	MAAAAA...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104051
Q96T76-2-unknown	MAAAAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111024
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111026
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111027
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111028
Q96T76-2-Acetylation	AAAAAV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111025
Q96T76-365-unknown	MKLVWP...	365		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000322236
Q96T76-365-unknown	MKLVWP...	365		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199189
Q96T76-365-unknown	MKLVWP...	365		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199190

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HGIQRE	238	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391765
...REVFQT	311	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409425
...GSPGS	1030	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GSPGS	1030	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76921
...GSPGS	1030	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76923
...GSPGS	1030	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76922

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)