Q99259: Glutamate decarboxylase 1

General Information

Protein names	- Glutamate decarboxylase 1 - 4.1.1.15 - 67 kDa glutamic acid decarboxylase - GAD-67 - Glutamate decarboxylase 67 kDa isoform
Gene names	GAD1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99259

1 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 3 of Glutamate decarboxylase 1 - Isoform 4 of Glutamate decarboxylase 1

Sequence View

        10         20         30         40         50         60
MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF LQRTNSLEEK
        70         80         90        100        110        120
SRLVSAFKER QSSKNLLSCE NSDRDARFRR TETDFSNLFA RDLLPAKNGE EQTVQFLLEV
       130        140        150        160        170        180
VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV
       190        200        210        220        230        240
RTGHPRFFNQ LSTGLDIIGL AGEWLTSTAN TNMFTYEIAP VFVLMEQITL KKMREIVGWS
       250        260        270        280        290        300
SKDGDGIFSP GGAISNMYSI MAARYKYFPE VKTKGMAAVP KLVLFTSEQS HYSIKKAGAA
       310        320        330        340        350        360
LGFGTDNVIL IKCNERGKII PADFEAKILE AKQKGYVPFY VNATAGTTVY GAFDPIQEIA
       370        380        390        400        410        420
DICEKYNLWL HVDAAWGGGL LMSRKHRHKL NGIERANSVT WNPHKMMGVL LQCSAILVKE
       430        440        450        460        470        480
KGILQGCNQM CAGYLFQPDK QYDVSYDTGD KAIQCGRHVD IFKFWLMWKA KGTVGFENQI
       490        500        510        520        530        540
NKCLELAEYL YAKIKNREEF EMVFNGEPEH TNVCFWYIPQ SLRGVPDSPQ RREKLHKVAP
       550        560        570        580        590
KIKALMMESG TTMVGYQPQG DKANFFRMVI SNPAATQSDI DFLIEEIERL GQDL         10         20         30         40         50         60
MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF LQRTNSLEEK
        70         80         90        100        110        120
SRLVSAFKER QSSKNLLSCE NSDRDARFRR TETDFSNLFA RDLLPAKNGE EQTVQFLLEV
       130        140        150        160        170        180
VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV
       190        200        210        220        230        240
RTGHPRFFNQ LSTGLDIIGL AGEWLTSTAN TNMFTYEIAP VFVLMEQITL KKMREIVGWS
       250        260        270        280        290        300
SKDGDGIFSP GGAISNMYSI MAARYKYFPE VKTKGMAAVP KLVLFTSEQS HYSIKKAGAA
       310        320        330        340        350        360
LGFGTDNVIL IKCNERGKII PADFEAKILE AKQKGYVPFY VNATAGTTVY GAFDPIQEIA
       370        380        390        400        410        420
DICEKYNLWL HVDAAWGGGL LMSRKHRHKL NGIERANSVT WNPHKMMGVL LQCSAILVKE
       430        440        450        460        470        480
KGILQGCNQM CAGYLFQPDK QYDVSYDTGD KAIQCGRHVD IFKFWLMWKA KGTVGFENQI
       490        500        510        520        530        540
NKCLELAEYL YAKIKNREEF EMVFNGEPEH TNVCFWYIPQ SLRGVPDSPQ RREKLHKVAP
       550        560        570        580        590
KIKALMMESG TTMVGYQPQG DKANFFRMVI SNPAATQSDI DFLIEEIERL GQDL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q99259-1-unknown	MASSTP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99259-1-unknown	MASSTP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72440
Q99259-1-unknown	MASSTP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72441

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...CGVAHG	37	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394948
...CGVAHG	37	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153794
...CGVAHG	37	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153795
...NSDRDA	85	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402366
...NSDRDA	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154195
...NSDRDA	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154196
...EQTVQF	115	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405917
...EQTVQF	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154529
...EQTVQF	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154530
...LLEVVD	121	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394255
...LLEVVD	121	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154608
...LLEVVD	121	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154609
...LGQDL	594	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)