Q99315: Transposon Ty3-G Gag-Pol polyprotein

General Information

Protein names	- Transposon Ty3-G Gag-Pol polyprotein - Gag3-Pol3 - Transposon Ty3-1 TYA-TYB polyprotein - Capsid protein - CA - p24 - Spacer peptide p3 - Nucleocapsid protein p11 - NC - Ty3 protease - PR - 3.4.23.- - p16 - Spacer peptide J - Reverse transcriptase/ribonuclease H - RT - RT-RH - 2.7.7.49 - 2.7.7.7 - 3.1.26.4 - p55 - Integrase p61 - IN - Integrase p58 - IN
Gene names	TY3B-G
Organism	Saccharomyces cerevisiae
Protease Family	A02.022
Protease ID	A02.022
Chromosome location
UniProt ID	Q99315

7 N-termini

8 C-termini

5 Cleavages

5 Substrates

Sequence

        10         20         30         40         50         60
MSFMDQIPGG GNYPKLPVEC LPNFPIQPSL TFRGRNDSHK LKNFISEIML NMSMISWPND
        70         80         90        100        110        120
ASRIVYCRRH LLNPAAQWAN DFVQEQGILE ITFDTFIQGL YQHFYKPPDI NKIFNAITQL
       130        140        150        160        170        180
SEAKLGIERL NQRFRKIWDR MPPDFMTEKA AIMTYTRLLT KETYNIVRMH KPETLKDAME
       190        200        210        220        230        240
EAYQTTALTE RFFPGFELDA DGDTIIGATT HLQEEYDSDY DSEDNLTQNG YVHTVRTRRS
       250        260        270        280        290        300
YNKPMSNHRN RRNNNPSREE CIKNRLCFYC KKEGHRLNEC RARKAVLTDL ELESKDQQTP
       310        320        330        340        350        360
FIKTLPIVHY IAIPEMDNTA EKTIKIQNTK VKTLFDSGSP TSFIRRDIVE LLKYEIYETP
       370        380        390        400        410        420
PLRFRGFVAT KSAVTSEAVT IDLKINDLHI TLAAYILDNM DYQLLIGNPI LRRYPKILHT
       430        440        450        460        470        480
VLNTRESPDS LKPKTYRSET VNNVRTYSAG NRGNPRNIKL SFAPTILEAT DPKSAGNRGD
       490        500        510        520        530        540
SRTKTLSLAT TTPAAIDPLT TLDNPGSTQS TFAQFPIPEE ASILEEDGKY SNVVSTIQSV
       550        560        570        580        590        600
EPNATDHSNK DTFCTLPVWL QQKYREIIRN DLPPRPADIN NIPVKHDIEI KPGARLPRLQ
       610        620        630        640        650        660
PYHVTEKNEQ EINKIVQKLL DNKFIVPSKS PCSSPVVLVP KKDGTFRLCV DYRTLNKATI
       670        680        690        700        710        720
SDPFPLPRID NLLSRIGNAQ IFTTLDLHSG YHQIPMEPKD RYKTAFVTPS GKYEYTVMPF
       730        740        750        760        770        780
GLVNAPSTFA RYMADTFRDL RFVNVYLDDI LIFSESPEEH WKHLDTVLER LKNENLIVKK
       790        800        810        820        830        840
KKCKFASEET EFLGYSIGIQ KIAPLQHKCA AIRDFPTPKT VKQAQRFLGM INYYRRFIPN
       850        860        870        880        890        900
CSKIAQPIQL FICDKSQWTE KQDKAIDKLK DALCNSPVLV PFNNKANYRL TTDASKDGIG
       910        920        930        940        950        960
AVLEEVDNKN KLVGVVGYFS KSLESAQKNY PAGELELLGI IKALHHFRYM LHGKHFTLRT
       970        980        990       1000       1010       1020
DHISLLSLQN KNEPARRVQR WLDDLATYDF TLEYLAGPKN VVADAISRAV YTITPETSRP
      1030       1040       1050       1060       1070       1080
IDTESWKSYY KSDPLCSAVL IHMKELTQHN VTPEDMSAFR SYQKKLELSE TFRKNYSLED
      1090       1100       1110       1120       1130       1140
EMIYYQDRLV VPIKQQNAVM RLYHDHTLFG GHFGVTVTLA KISPIYYWPK LQHSIIQYIR
      1150       1160       1170       1180       1190       1200
TCVQCQLIKS HRPRLHGLLQ PLPIAEGRWL DISMDFVTGL PPTSNNLNMI LVVVDRFSKR
      1210       1220       1230       1240       1250       1260
AHFIATRKTL DATQLIDLLF RYIFSYHGFP RTITSDRDVR MTADKYQELT KRLGIKSTMS
      1270       1280       1290       1300       1310       1320
SANHPQTDGQ SERTIQTLNR LLRAYASTNI QNWHVYLPQI EFVYNSTPTR TLGKSPFEID
      1330       1340       1350       1360       1370       1380
LGYLPNTPAI KSDDEVNARS FTAVELAKHL KALTIQTKEQ LEHAQIEMET NNNQRRKPLL
      1390       1400       1410       1420       1430       1440
LNIGDHVLVH RDAYFKKGAY MKVQQIYVGP FRVVKKINDN AYELDLNSHK KKHRVINVQF
      1450       1460       1470       1480       1490       1500
LKKFVYRPDA YPKNKPISST ERIKRAHEVT ALIGIDTTHK TYLCHMQDVD PTLSVEYSEA
      1510       1520       1530       1540
EFCQIPERTR RSILANFRQL YETQDNPERE EDVVSQNEIC QYDNTSP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 8 C-termini - 5 Cleavages - 5 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q99315-2-unknown	MSFMDQ...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-2-Acetylation	SFMDQI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-234-unknown	TVRTRR...	234		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-234-unknown	TVRTRR...	234		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32642
Q99315-310-unknown	YIAIPE...	310		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-310-unknown	YIAIPE...	310		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32643
Q99315-536-unknown	TIQSVE...	536		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-536-unknown	TIQSVE...	536		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32644
Q99315-1012-unknown	TITPET...	1012		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-1012-unknown	TITPET...	1012		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32645
Q99315-1038-unknown	AVLIHM...	1038		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99315-1038-unknown	AVLIHM...	1038		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32646

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTIIGA	207	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NGYVHT	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32642
...LPIVHY	309	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LPIVHY	309	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32643
...SETVNN	442	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SNVVST	535	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32644
...SRAVYT	1011	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SRAVYT	1011	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32645
...DPLCSA	1037	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32646
...DNTSP	1547	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
YG31B_YEAST	233	YVHT.\|.TVRT	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @233
YG31B_YEAST	309	IVHY.\|.YIAI	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @309
YG31B_YEAST	535	VVST.\|.TIQS	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @535
YG31B_YEAST	1011	AVYT.\|.TITP	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @1011
YG31B_YEAST	1037	LCSA.\|.AVLI	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @1037

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
YG31B_YEAST	233	YVHT.\|.TVRT	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @233
YG31B_YEAST	309	IVHY.\|.YIAI	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @309
YG31B_YEAST	535	VVST.\|.TIQS	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @535
YG31B_YEAST	1011	AVYT.\|.TITP	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @1011
YG31B_YEAST	1037	LCSA.\|.AVLI	inferred from experiment	unknown	MEROPS	Merops YG31B_YEAST -> YG31B_YEAST @1037