Q99571: P2X purinoceptor 4

General Information

Protein names	- P2X purinoceptor 4 - P2X4 - ATP receptor - Purinergic receptor
Gene names	P2RX4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99571

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of P2X purinoceptor 4 - Isoform 3 of P2X purinoceptor 4

Sequence View

        10         20         30         40         50         60
MAGCCAALAA FLFEYDTPRI VLIRSRKVGL MNRAVQLLIL AYVIGWVFVW EKGYQETDSV
        70         80         90        100        110        120
VSSVTTKVKG VAVTNTSKLG FRIWDVADYV IPAQEENSLF VMTNVILTMN QTQGLCPEIP
       130        140        150        160        170        180
DATTVCKSDA SCTAGSAGTH SNGVSTGRCV AFNGSVKTCE VAAWCPVEDD THVPQPAFLK
       190        200        210        220        230        240
AAENFTLLVK NNIWYPKFNF SKRNILPNIT TTYLKSCIYD AKTDPFCPIF RLGKIVENAG
       250        260        270        280        290        300
HSFQDMAVEG GIMGIQVNWD CNLDRAASLC LPRYSFRRLD TRDVEHNVSP GYNFRFAKYY
       310        320        330        340        350        360
RDLAGNEQRT LIKAYGIRFD IIVFGKAGKF DIIPTMINIG SGLALLGMAT VLCDIIVLYC
       370        380
MKKRLYYREK KYKYVEDYEQ GLASELDQ         10         20         30         40         50         60
MAGCCAALAA FLFEYDTPRI VLIRSRKVGL MNRAVQLLIL AYVIGWVFVW EKGYQETDSV
        70         80         90        100        110        120
VSSVTTKVKG VAVTNTSKLG FRIWDVADYV IPAQEENSLF VMTNVILTMN QTQGLCPEIP
       130        140        150        160        170        180
DATTVCKSDA SCTAGSAGTH SNGVSTGRCV AFNGSVKTCE VAAWCPVEDD THVPQPAFLK
       190        200        210        220        230        240
AAENFTLLVK NNIWYPKFNF SKRNILPNIT TTYLKSCIYD AKTDPFCPIF RLGKIVENAG
       250        260        270        280        290        300
HSFQDMAVEG GIMGIQVNWD CNLDRAASLC LPRYSFRRLD TRDVEHNVSP GYNFRFAKYY
       310        320        330        340        350        360
RDLAGNEQRT LIKAYGIRFD IIVFGKAGKF DIIPTMINIG SGLALLGMAT VLCDIIVLYC
       370        380
MKKRLYYREK KYKYVEDYEQ GLASELDQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q99571-1-unknown	MAGCCA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99571-1-unknown	MAGCCA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84003
Q99571-1-unknown	MAGCCA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84004
Q99571-102-unknown	MTNVIL...	102	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000438131
Q99571-102-unknown	MTNVIL...	102	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132299
Q99571-102-unknown	MTNVIL...	102	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132298

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPRYSF	275	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444033
...LPRYSF	275	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113551
...LPRYSF	275	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113550
...SELDQ	388	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SELDQ	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79622
...SELDQ	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79621

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)