Q99685: Monoglyceride lipase {ECO:0000303|PubMed:11470505}

General Information

Protein names	- Monoglyceride lipase {ECO:0000303\|PubMed:11470505} - MGL {ECO:0000312\|HGNC:HGNC:17038} - 3.1.1.23 {ECO:0000269\|PubMed:19029917, ECO:0000269\|PubMed:20079333, ECO:0000269\|PubMed:21049984, ECO:0000269\|PubMed:22969151, ECO:0000269\|PubMed:24368842} - HU-K5 {ECO:0000303\|PubMed:9495531} - Lysophospholipase homolog - Lysophospholipase-like - Monoacylglycerol lipase {ECO:0000303\|PubMed:20079333} - MAGL {ECO:0000303\|PubMed:20079333}
Gene names	MGLL
Organism	Homo sapiens
Protease Family
Protease ID	S33.980
Chromosome location
UniProt ID	Q99685

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE
        70         80         90        100        110        120
LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG
       130        140        150        160        170        180
HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV LPNLSLGPID
       190        200        210        220        230        240
SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP FLLLQGSADR
       250        260        270        280        290        300
LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV SQRTATAGTA

SPP

Isoforms

- Isoform 2 of Monoglyceride lipase

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99685-1-unknown	MPEESS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99685-1-unknown	MPEESS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107809
Q99685-2-unknown	PEESSP...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q99685-2-unknown	PEESSP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178885
Q99685-64-unknown	MLMGLD...	64	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417689
Q99685-64-unknown	MLMGLD...	64	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131890

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...FAHDHV	77	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417489
...FAHDHV	77	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt112669
...LVLANP	152	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417689
...LVLANP	152	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt112667
...TASPP	303		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...TASPP	303	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...TASPP	303	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt76644
...TASPP	303		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)