Q99741: Cell division control protein 6 homolog

General Information

Protein names	- Cell division control protein 6 homolog - CDC6-related protein - Cdc18-related protein - HsCdc18 - p62(cdc6) - HsCDC6
Gene names	CDC6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99741

3 N-termini

6 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPQTRSQAQA TISFPKRKLS RALNKAKNSS DAKLEPTNVQ TVTCSPRVKA LPLSPRKRLG
        70         80         90        100        110        120
DDNLCNTPHL PPCSPPKQGK KENGPPHSHT LKGRRLVFDN QLTIKSPSKR ELAKVHQNKI
       130        140        150        160        170        180
LSSVRKSQEI TTNSEQRCPL KKESACVRLF KQEGTCYQQA KLVLNTAVPD RLPAREREMD
       190        200        210        220        230        240
VIRNFLREHI CGKKAGSLYL SGAPGTGKTA CLSRILQDLK KELKGFKTIM LNCMSLRTAQ
       250        260        270        280        290        300
AVFPAIAQEI CQEEVSRPAG KDMMRKLEKH MTAEKGPMIV LVLDEMDQLD SKGQDVLYTL
       310        320        330        340        350        360
FEWPWLSNSH LVLIGIANTL DLTDRILPRL QAREKCKPQL LNFPPYTRNQ IVTILQDRLN
       370        380        390        400        410        420
QVSRDQVLDN AAVQFCARKV SAVSGDVRKA LDVCRRAIEI VESDVKSQTI LKPLSECKSP
       430        440        450        460        470        480
SEPLIPKRVG LIHISQVISE VDGNRMTLSQ EGAQDSFPLQ QKILVCSLML LIRQLKIKEV
       490        500        510        520        530        540
TLGKLYEAYS KVCRKQQVAA VDQSECLSLS GLLEARGILG LKRNKETRLT KVFFKIEEKE
       550        560
IEHALKDKAL IGNILATGLP

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q99741-1-unknown	MPQTRS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99741-100-unknown	NQLTIK...	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2313
Q99741-443-unknown	GNRMTL...	443	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2314

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLVFDN	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2313
...LVFDNQ	100	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463004
...KVHQNK	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464047
...EMDVIR	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463635
...ISEVDG	442	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2314
...ATGLP	560	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	99	VFDN.\|.NQLT	inferred from experiment	unknown	MEROPS	Laskey RA	Pelizon C et al.:Human replication protein Cdc6 ... (C14.003)	12151338,
CASP3_HUMAN	442	EVDG.\|.GNRM	inferred from experiment	unknown	MEROPS	Laskey RA	Pelizon C et al.:Human replication protein Cdc6 ... (C14.003)	12151338,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)