TopFIND 4.0

Q99814: Endothelial PAS domain-containing protein 1

General Information

Protein names
- Endothelial PAS domain-containing protein 1
- EPAS-1
- Basic-helix-loop-helix-PAS protein MOP2
- Class E basic helix-loop-helix protein 73
- bHLHe73
- HIF-1-alpha-like factor
- HLF
- Hypoxia-inducible factor 2-alpha
- HIF-2-alpha
- HIF2-alpha
- Member of PAS protein 2
- PAS domain-containing protein 2
Gene names EPAS1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q99814

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTADKEKKRS SSERRKEKSR DAARCRRSKE TEVFYELAHE LPLPHSVSSH LDKASIMRLA 
        70         80         90        100        110        120 
ISFLRTHKLL SSVCSENESE AEADQQMDNL YLKALEGFIA VVTQDGDMIF LSENISKFMG 
       130        140        150        160        170        180 
LTQVELTGHS IFDFTHPCDH EEIRENLSLK NGSGFGKKSK DMSTERDFFM RMKCTVTNRG 
       190        200        210        220        230        240 
RTVNLKSATW KVLHCTGQVK VYNNCPPHNS LCGYKEPLLS CLIIMCEPIQ HPSHMDIPLD 
       250        260        270        280        290        300 
SKTFLSRHSM DMKFTYCDDR ITELIGYHPE ELLGRSAYEF YHALDSENMT KSHQNLCTKG 
       310        320        330        340        350        360 
QVVSGQYRML AKHGGYVWLE TQGTVIYNPR NLQPQCIMCV NYVLSEIEKN DVVFSMDQTE 
       370        380        390        400        410        420 
SLFKPHLMAM NSIFDSSGKG AVSEKSNFLF TKLKEEPEEL AQLAPTPGDA IISLDFGNQN 
       430        440        450        460        470        480 
FEESSAYGKA ILPPSQPWAT ELRSHSTQSE AGSLPAFTVP QAAAPGSTTP SATSSSSSCS 
       490        500        510        520        530        540 
TPNSPEDYYT SLDNDLKIEV IEKLFAMDTE AKDQCSTQTD FNELDLETLA PYIPMDGEDF 
       550        560        570        580        590        600 
QLSPICPEER LLAENPQSTP QHCFSAMTNI FQPLAPVAPH SPFLLDKFQQ QLESKKTEPE 
       610        620        630        640        650        660 
HRPMSSIFFD AGSKASLPPC CGQASTPLSS MGGRSNTQWP PDPPLHFGPT KWAVGDQRTE 
       670        680        690        700        710        720 
FLGAAPLGPP VSPPHVSTFK TRSAKGFGAR GPDVLSPAMV ALSNKLKLKR QLEYEEQAFQ 
       730        740        750        760        770        780 
DLSGGDPPGG STSHLMWKRM KNLRGGSCPL MPDKPLSANV PNDKFTQNPM RGLGHPLRHL 
       790        800        810        820        830        840 
PLPQPPSAIS PGENSKSRFP PQCYATQYQD YSLSSAHKVS GMASRLLGPS FESYLLPELT 
       850        860        870    
RYDCEVNVPV LGSSTLLQGG DLLRALDQAT 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q99814-1-unknown MTADKE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)