TopFIND 4.0

Q99932: Sperm-associated antigen 8

General Information

Protein names
- Sperm-associated antigen 8
- HSD-1
- Sperm membrane protein 1
- SMP-1
- Sperm membrane protein BS-84
Gene names SPAG8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q99932

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
METNESTEGS RSRSRSLDIQ PSSEGLGPTS EPFPSSDDSP RSALAAATAA AAAAASAAAA 
        70         80         90        100        110        120 
TAAFTTAKAA ALSTKTPAPC SEFMEPSSDP SLLGEPCAGP GFTHNIAHGS LGFEPVYVSC 
       130        140        150        160        170        180 
IAQDTCTTTD HSSNPGPVPG SSSGPVLGSS SGAGHGSGSG SGPGCGSVPG SGSGPGPGSG 
       190        200        210        220        230        240 
PGSGPGHGSG SHPGPASGPG PDTGPDSELS PCIPPGFRNL VADRVPNYTS WSQHCPWEPQ 
       250        260        270        280        290        300 
KQPPWEFLQV LEPGARGLWK PPDIKGKLMV CYETLPRGQC LLYNWEEERA TNHLDQVPSM 
       310        320        330        340        350        360 
QDGSESFFFR HGHRGLLTMQ LKSPMPSSTT QKDSYQPPGN VYWPLRGKRE AMLEMLLQHQ 
       370        380        390        400        410        420 
ICKEVQAEQE PTRKLFEVES VTHHDYRMEL AQAGTPAPTK PHDYRQEQPE TFWIQRAPQL 
       430        440        450        460        470        480 
PGVSNIRTLD TPFRKNCSFS TPVPLSLGKL LPYEPENYPY QLGEISSLPC PGGRLGGGGG 
   
RMTPF

Isoforms

- Isoform 2 of Sperm-associated antigen 8 - Isoform 3 of Sperm-associated antigen 8 - Isoform 1 of Sperm-associated antigen 8

Sequence View

        10         20         30         40         50         60 
METNESTEGS RSRSRSLDIQ PSSEGLGPTS EPFPSSDDSP RSALAAATAA AAAAASAAAA 
        70         80         90        100        110        120 
TAAFTTAKAA ALSTKTPAPC SEFMEPSSDP SLLGEPCAGP GFTHNIAHGS LGFEPVYVSC 
       130        140        150        160        170        180 
IAQDTCTTTD HSSNPGPVPG SSSGPVLGSS SGAGHGSGSG SGPGCGSVPG SGSGPGPGSG 
       190        200        210        220        230        240 
PGSGPGHGSG SHPGPASGPG PDTGPDSELS PCIPPGFRNL VADRVPNYTS WSQHCPWEPQ 
       250        260        270        280        290        300 
KQPPWEFLQV LEPGARGLWK PPDIKGKLMV CYETLPRGQC LLYNWEEERA TNHLDQVPSM 
       310        320        330        340        350        360 
QDGSESFFFR HGHRGLLTMQ LKSPMPSSTT QKDSYQPPGN VYWPLRGKRE AMLEMLLQHQ 
       370        380        390        400        410        420 
ICKEVQAEQE PTRKLFEVES VTHHDYRMEL AQAGTPAPTK PHDYRQEQPE TFWIQRAPQL 
       430        440        450        460        470        480 
PGVSNIRTLD TPFRKNCSFS TPVPLSLGKL LPYEPENYPY QLGEISSLPC PGGRLGGGGG 
   
RMTPF         10         20         30         40         50         60 
METNESTEGS RSRSRSLDIQ PSSEGLGPTS EPFPSSDDSP RSALAAATAA AAAAASAAAA 
        70         80         90        100        110        120 
TAAFTTAKAA ALSTKTPAPC SEFMEPSSDP SLLGEPCAGP GFTHNIAHGS LGFEPVYVSC 
       130        140        150        160        170        180 
IAQDTCTTTD HSSNPGPVPG SSSGPVLGSS SGAGHGSGSG SGPGCGSVPG SGSGPGPGSG 
       190        200        210        220        230        240 
PGSGPGHGSG SHPGPASGPG PDTGPDSELS PCIPPGFRNL VADRVPNYTS WSQHCPWEPQ 
       250        260        270        280        290        300 
KQPPWEFLQV LEPGARGLWK PPDIKGKLMV CYETLPRGQC LLYNWEEERA TNHLDQVPSM 
       310        320        330        340        350        360 
QDGSESFFFR HGHRGLLTMQ LKSPMPSSTT QKDSYQPPGN VYWPLRGKRE AMLEMLLQHQ 
       370        380        390        400        410        420 
ICKEVQAEQE PTRKLFEVES VTHHDYRMEL AQAGTPAPTK PHDYRQEQPE TFWIQRAPQL 
       430        440        450        460        470        480 
PGVSNIRTLD TPFRKNCSFS TPVPLSLGKL LPYEPENYPY QLGEISSLPC PGGRLGGGGG 
   
RMTPF         10         20         30         40         50         60 
METNESTEGS RSRSRSLDIQ PSSEGLGPTS EPFPSSDDSP RSALAAATAA AAAAASAAAA 
        70         80         90        100        110        120 
TAAFTTAKAA ALSTKTPAPC SEFMEPSSDP SLLGEPCAGP GFTHNIAHGS LGFEPVYVSC 
       130        140        150        160        170        180 
IAQDTCTTTD HSSNPGPVPG SSSGPVLGSS SGAGHGSGSG SGPGCGSVPG SGSGPGPGSG 
       190        200        210        220        230        240 
PGSGPGHGSG SHPGPASGPG PDTGPDSELS PCIPPGFRNL VADRVPNYTS WSQHCPWEPQ 
       250        260        270        280        290        300 
KQPPWEFLQV LEPGARGLWK PPDIKGKLMV CYETLPRGQC LLYNWEEERA TNHLDQVPSM 
       310        320        330        340        350        360 
QDGSESFFFR HGHRGLLTMQ LKSPMPSSTT QKDSYQPPGN VYWPLRGKRE AMLEMLLQHQ 
       370        380        390        400        410        420 
ICKEVQAEQE PTRKLFEVES VTHHDYRMEL AQAGTPAPTK PHDYRQEQPE TFWIQRAPQL 
       430        440        450        460        470        480 
PGVSNIRTLD TPFRKNCSFS TPVPLSLGKL LPYEPENYPY QLGEISSLPC PGGRLGGGGG 
   
RMTPF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q99932-1-unknown METNES... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q99932-1-unknown METNES... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90360
    Q99932-1-unknown METNES... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90361

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GVSNIR 426 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)