TopFIND 4.0

Q99JN2: Kelch-like protein 22 {ECO:0000305}

General Information

Protein names
- Kelch-like protein 22 {ECO:0000305}
Gene names Klhl22
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q99JN2

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAEEQDFAQL CRLPTQPSHS HCVNNTYRST QHSQALLRGL LALRDSGILF DVVLVVEGKH 
        70         80         90        100        110        120 
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 
       130        140        150        160        170        180 
QETLVAACQL QIPEIIHFCC DFLMSWVDEE NILDVYRLAD LFDLNHLTQQ LDTYILKNFV 
       190        200        210        220        230        240 
AFSRTDKYRQ LPLEKVYSLL SSNRLEVSCE TEVYEGALLY HYSLEQVQAD QISLNEPPKL 
       250        260        270        280        290        300 
LETVRFPLME AEVLQRLHDK LGPSPLRDTV ASALMYHRNE ILQPSLQGPQ TELRSDFQCV 
       310        320        330        340        350        360 
VGFGGIHSTP STILSDQAKY LNPLLGEWKH FTASLAPRMS NQGIAVLNNF VYLIGGDNNV 
       370        380        390        400        410        420 
QGFRAESRCW RYDPRHNRWF QIQSLQQEHA DLCVCVVGKY IYAVAGRDYH NDLSAVERYD 
       430        440        450        460        470        480 
PATNSWDYVA PLKKEVYAHA GTTLQGKMYI TCGRRGEDYL KETHCYDPGS NTWHTLADGP 
       490        500        510        520        530        540 
VRRAWHGMAA LLDKLFVIGG SNNDAGYRRD VHQVACYSCT SRQWSSVCPL PAGHGEPGIA 
       550        560        570        580        590        600 
VLDSRIYVLG GRSHNRGSRT GYVHIYDMEK DCWEEGPQLN NSISGLAACV LTLPRSLLHE 
       610        620        630    
QPRGTPNRSQ ADADFASEVM SVSDWEEFDN SSED

Isoforms

- Isoform 2 of Kelch-like protein 22

Sequence View

        10         20         30         40         50         60 
MAEEQDFAQL CRLPTQPSHS HCVNNTYRST QHSQALLRGL LALRDSGILF DVVLVVEGKH 
        70         80         90        100        110        120 
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 
       130        140        150        160        170        180 
QETLVAACQL QIPEIIHFCC DFLMSWVDEE NILDVYRLAD LFDLNHLTQQ LDTYILKNFV 
       190        200        210        220        230        240 
AFSRTDKYRQ LPLEKVYSLL SSNRLEVSCE TEVYEGALLY HYSLEQVQAD QISLNEPPKL 
       250        260        270        280        290        300 
LETVRFPLME AEVLQRLHDK LGPSPLRDTV ASALMYHRNE ILQPSLQGPQ TELRSDFQCV 
       310        320        330        340        350        360 
VGFGGIHSTP STILSDQAKY LNPLLGEWKH FTASLAPRMS NQGIAVLNNF VYLIGGDNNV 
       370        380        390        400        410        420 
QGFRAESRCW RYDPRHNRWF QIQSLQQEHA DLCVCVVGKY IYAVAGRDYH NDLSAVERYD 
       430        440        450        460        470        480 
PATNSWDYVA PLKKEVYAHA GTTLQGKMYI TCGRRGEDYL KETHCYDPGS NTWHTLADGP 
       490        500        510        520        530        540 
VRRAWHGMAA LLDKLFVIGG SNNDAGYRRD VHQVACYSCT SRQWSSVCPL PAGHGEPGIA 
       550        560        570        580        590        600 
VLDSRIYVLG GRSHNRGSRT GYVHIYDMEK DCWEEGPQLN NSISGLAACV LTLPRSLLHE 
       610        620        630    
QPRGTPNRSQ ADADFASEVM SVSDWEEFDN SSED



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q99JN2-1-unknown MAEEQD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79104
    Q99JN2-2-unknown MAEEQD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q99JN2-2-Acetylation AEEQDF... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q99JN2-2-Acetylation AEEQDF... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110530

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NSSED 634 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)