TopFIND 4.0

Q99MI7: NEDD8-activating enzyme E1 catalytic subunit

General Information

Protein names
- NEDD8-activating enzyme E1 catalytic subunit
- 6.2.1.-
- NEDD8-activating enzyme E1C
- Ubiquitin-activating enzyme E1C
- Ubiquitin-like modifier-activating enzyme 3
- Ubiquitin-activating enzyme 3
Gene names Uba3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q99MI7

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADGEEPEKK RRRIEELLAE KMAVDGGCGD TGDWEGRWNH VKKFLERSGP FTHPDFEPST 
        70         80         90        100        110        120 
ESLQFLLDTC KVLVIGAGGL GCELLKNLAL SGFRQIHVID MDTIDVSNLN RQFLFRPKDV 
       130        140        150        160        170        180 
GRPKAEVAAE FLNDRVPNCN VVPHFNKIQD FNDTFYRQFH IIVCGLDSII ARRWINGMLI 
       190        200        210        220        230        240 
SLLNYEDGVL DPSSIVPLID GGTEGFKGNA RVILPGMTAC IECTLELYPP QVNFPMCTIA 
       250        260        270        280        290        300 
SMPRLPEHCI EYVRMLQWPK EQPFGDGVPL DGDDPEHIQW IFQKSVERAS QYNIRGVTYR 
       310        320        330        340        350        360 
LTQGVVKRII PAVASTNAVI AAVCATEVFK IATSAYIPLN NYLVFNDVDG LYTYTFEAER 
       370        380        390        400        410        420 
KENCPACSQL PQNIQFSPSA KLQEVLDYLT NSASLQMKSP AITATLEGKN RTLYLQSVTS 
       430        440        450        460    
IEERTRPNLS KTLKELGLVD GQELAVADVT TPQTVLFKLH FT

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q99MI7-2-unknown MADGEE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q99MI7-2-Acetylation ADGEEP... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KLHFT 462 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)