Q99MK8: Beta-adrenergic receptor kinase 1

General Information

Protein names	- Beta-adrenergic receptor kinase 1 - Beta-ARK-1 - 2.7.11.15 - G-protein-coupled receptor kinase 2 {ECO:0000312\|MGI:MGI:87940}
Gene names	Adrbk1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99MK8

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADLEAVLAD VSYLMAMEKS KATPAARASK KILLPEPSIR SVMQKYLEDR GEVTFEKIFS
        70         80         90        100        110        120
QKLGYLLFRD FCLNHLEEAK PLVEFYEEIK KYEKLETEEE RVVRSREIFD SYIMKELLAC
       130        140        150        160        170        180
SHPFSKNATE HVQGHLVKKQ VPPDLFQPYI EEICQNLRGD VFQKFIESDK FTRFCQWKNV
       190        200        210        220        230        240
ELNIHLTMND FSVHRIIGRG GFGEVYGCRK ADTGKMYAMK CLDKKRIKMK QGETLALNER
       250        260        270        280        290        300
IMLSLVSTGD CPFIVCMSYA FHTPDKLSFI LDLMNGGDLH YHLSQHGVFS EADMRFYAAE
       310        320        330        340        350        360
IILGLEHMHN RFVVYRDLKP ANILLDEHGH VRISDLGLAC DFSKKRPHAS VGTHGYMAPE
       370        380        390        400        410        420
VLQKGVAYDS SADWFSLGCM LFKLLRGHSP FRQHKTKDKH EIDRMTLTMA VELPDSFSPE
       430        440        450        460        470        480
LRSLLEGLLQ RDVNRRLGCL GRGAQEVKES PFFRSLDWQM VFLQKYPPPL IPPRGEVNAA
       490        500        510        520        530        540
DAFDIGSFDE EDTKGIKLLD SDQELYRNFP LTISERWQQE VAETVFDTIN AETDRLEARK
       550        560        570        580        590        600
KAKNKQLGHE EDYALGKDCI VHGYMSKMGN PFLTQWQRRY FYLFPNRLEW RGEGEAPQSL
       610        620        630        640        650        660
LTMEEIQSVE ETQIKERKCL LLKIRGGKQF VLQCDSDPEL VQWKKELRDA YREAQQLVQR
       670        680
VPKMKNKPRS PVVELSKVPL IQRGSANGL

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99MK8-1-unknown	MADLEA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99MK8-43-unknown	MQKYLE...	43		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000025791

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DSYIMK	114	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000129839
...FDEEDT	492	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000128177
...SANGL	689	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)