TopFIND 4.0

Q99NH8: Triggering receptor expressed on myeloid cells 2

General Information

Protein names
- Triggering receptor expressed on myeloid cells 2
- TREM-2
- Triggering receptor expressed on monocytes 2
Gene names Trem2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q99NH8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPLHQFLLL LITALSQALN TTVLQGMAGQ SLRVSCTYDA LKHWGRRKAW CRQLGEEGPC 
        70         80         90        100        110        120 
QRVVSTHGVW LLAFLKKRNG STVIADDTLA GTVTITLKNL QAGDAGLYQC QSLRGREAEV 
       130        140        150        160        170        180 
LQKVLVEVLE DPLDDQDAGD LWVPEESSSF EGAQVEHSTS RNQETSFPPT SILLLLACVL 
       190        200        210        220    
LSKFLAASIL WAVARGRQKP GTPVVRGLDC GQDAGHQLQI LTGPGGT

Isoforms

- Isoform 2 of Triggering receptor expressed on myeloid cells 2

Sequence View

        10         20         30         40         50         60 
MGPLHQFLLL LITALSQALN TTVLQGMAGQ SLRVSCTYDA LKHWGRRKAW CRQLGEEGPC 
        70         80         90        100        110        120 
QRVVSTHGVW LLAFLKKRNG STVIADDTLA GTVTITLKNL QAGDAGLYQC QSLRGREAEV 
       130        140        150        160        170        180 
LQKVLVEVLE DPLDDQDAGD LWVPEESSSF EGAQVEHSTS RNQETSFPPT SILLLLACVL 
       190        200        210        220    
LSKFLAASIL WAVARGRQKP GTPVVRGLDC GQDAGHQLQI LTGPGGT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q99NH8-1-unknown MGPLHQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92979
    Q99NH8-19-unknown LNTTVL... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q99NH8-19-unknown LNTTVL... 19 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112207

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GPGGT 227 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)