Q9BPZ7: Target of rapamycin complex 2 subunit MAPKAP1

General Information

Protein names	- Target of rapamycin complex 2 subunit MAPKAP1 - TORC2 subunit MAPKAP1 - Mitogen-activated protein kinase 2-associated protein 1 - Stress-activated map kinase-interacting protein 1 - SAPK-interacting protein 1 - mSIN1
Gene names	MAPKAP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BPZ7

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Target of rapamycin complex 2 subunit MAPKAP1 - Isoform 3 of Target of rapamycin complex 2 subunit MAPKAP1 - Isoform 4 of Target of rapamycin complex 2 subunit MAPKAP1 - Isoform 5 of Target of rapamycin complex 2 subunit MAPKAP1 - Isoform 6 of Target of rapamycin complex 2 subunit MAPKAP1

Sequence View

        10         20         30         40         50         60
MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE
        70         80         90        100        110        120
TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL
       130        140        150        160        170        180
KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY
       190        200        210        220        230        240
LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEGRE PKLNDNVSAY CLHIAEDDGE
       250        260        270        280        290        300
VDTDFPPLDS NEPIHKFGFS TLALVEKYSS PGLTSKESLF VRINAAHGFS LIQVDNTKVT
       310        320        330        340        350        360
MKEILLKAVK RRKGSQKVSG PQYRLEKQSE PNVAVDLDST LESQSAWEFC LVRENSSRAD
       370        380        390        400        410        420
GVFEEDSQID IATVQDMLSS HHYKSFKVSM IHRLRFTTDV QLGISGDKVE IDPVTNQKAS
       430        440        450        460        470        480
TKFWIKQKPI SIDSDLLCAC DLAEEKSPSH AIFKLTYLSN HDYKHLYFES DAATVNEIVL
       490        500        510        520
KVNYILESRA STARADYFAQ KQRKLNRRTS FSFQKEKKSG QQ         10         20         30         40         50         60
MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE
        70         80         90        100        110        120
TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL
       130        140        150        160        170        180
KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY
       190        200        210        220        230        240
LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEGRE PKLNDNVSAY CLHIAEDDGE
       250        260        270        280        290        300
VDTDFPPLDS NEPIHKFGFS TLALVEKYSS PGLTSKESLF VRINAAHGFS LIQVDNTKVT
       310        320        330        340        350        360
MKEILLKAVK RRKGSQKVSG PQYRLEKQSE PNVAVDLDST LESQSAWEFC LVRENSSRAD
       370        380        390        400        410        420
GVFEEDSQID IATVQDMLSS HHYKSFKVSM IHRLRFTTDV QLGISGDKVE IDPVTNQKAS
       430        440        450        460        470        480
TKFWIKQKPI SIDSDLLCAC DLAEEKSPSH AIFKLTYLSN HDYKHLYFES DAATVNEIVL
       490        500        510        520
KVNYILESRA STARADYFAQ KQRKLNRRTS FSFQKEKKSG QQ         10         20         30         40         50         60
MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE
        70         80         90        100        110        120
TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL
       130        140        150        160        170        180
KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY
       190        200        210        220        230        240
LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEGRE PKLNDNVSAY CLHIAEDDGE
       250        260        270        280        290        300
VDTDFPPLDS NEPIHKFGFS TLALVEKYSS PGLTSKESLF VRINAAHGFS LIQVDNTKVT
       310        320        330        340        350        360
MKEILLKAVK RRKGSQKVSG PQYRLEKQSE PNVAVDLDST LESQSAWEFC LVRENSSRAD
       370        380        390        400        410        420
GVFEEDSQID IATVQDMLSS HHYKSFKVSM IHRLRFTTDV QLGISGDKVE IDPVTNQKAS
       430        440        450        460        470        480
TKFWIKQKPI SIDSDLLCAC DLAEEKSPSH AIFKLTYLSN HDYKHLYFES DAATVNEIVL
       490        500        510        520
KVNYILESRA STARADYFAQ KQRKLNRRTS FSFQKEKKSG QQ         10         20         30         40         50         60
MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE
        70         80         90        100        110        120
TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL
       130        140        150        160        170        180
KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY
       190        200        210        220        230        240
LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEGRE PKLNDNVSAY CLHIAEDDGE
       250        260        270        280        290        300
VDTDFPPLDS NEPIHKFGFS TLALVEKYSS PGLTSKESLF VRINAAHGFS LIQVDNTKVT
       310        320        330        340        350        360
MKEILLKAVK RRKGSQKVSG PQYRLEKQSE PNVAVDLDST LESQSAWEFC LVRENSSRAD
       370        380        390        400        410        420
GVFEEDSQID IATVQDMLSS HHYKSFKVSM IHRLRFTTDV QLGISGDKVE IDPVTNQKAS
       430        440        450        460        470        480
TKFWIKQKPI SIDSDLLCAC DLAEEKSPSH AIFKLTYLSN HDYKHLYFES DAATVNEIVL
       490        500        510        520
KVNYILESRA STARADYFAQ KQRKLNRRTS FSFQKEKKSG QQ         10         20         30         40         50         60
MAFLDNPTII LAHIRQSHVT SDDTGMCEMV LIDHDVDLEK IHPPSMPGDS GSEIQGSNGE
        70         80         90        100        110        120
TQGYVYAQSV DITSSWDFGI RRRSNTAQRL ERLRKERQNQ IKCKNIQWKE RNSKQSAQEL
       130        140        150        160        170        180
KSLFEKKSLK EKPPISGKQS ILSVRLEQCP LQLNNPFNEY SKFDGKGHVG TTATKKIDVY
       190        200        210        220        230        240
LPLHSSQDRL LPMTVVTMAS ARVQDLIGLI CWQYTSEGRE PKLNDNVSAY CLHIAEDDGE
       250        260        270        280        290        300
VDTDFPPLDS NEPIHKFGFS TLALVEKYSS PGLTSKESLF VRINAAHGFS LIQVDNTKVT
       310        320        330        340        350        360
MKEILLKAVK RRKGSQKVSG PQYRLEKQSE PNVAVDLDST LESQSAWEFC LVRENSSRAD
       370        380        390        400        410        420
GVFEEDSQID IATVQDMLSS HHYKSFKVSM IHRLRFTTDV QLGISGDKVE IDPVTNQKAS
       430        440        450        460        470        480
TKFWIKQKPI SIDSDLLCAC DLAEEKSPSH AIFKLTYLSN HDYKHLYFES DAATVNEIVL
       490        500        510        520
KVNYILESRA STARADYFAQ KQRKLNRRTS FSFQKEKKSG QQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9BPZ7-2-unknown	MAFLDN...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BPZ7-1-unknown	MAFLDN...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89769
Q9BPZ7-1-unknown	MAFLDN...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89770
Q9BPZ7-1-unknown	MAFLDN...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89772
Q9BPZ7-1-unknown	MAFLDN...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89773
Q9BPZ7-2-Acetylation	AFLDNP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BPZ7-2-Acetylation	AFLDNP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110854
Q9BPZ7-2-Acetylation	AFLDNP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110855
Q9BPZ7-2-Acetylation	AFLDNP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110856
Q9BPZ7-2-Acetylation	AFLDNP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110857
Q9BPZ7-193-unknown	MTVVTM...	193		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89771
Q9BPZ7-193-unknown	MTVVTM...	193		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105457
Q9BPZ7-193-unknown	MTVVTM...	193		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105458
Q9BPZ7-193-unknown	MTVVTM...	193		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105459
Q9BPZ7-193-unknown	MTVVTM...	193		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105460

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KSGQQ	522		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KSGQQ	522		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KSGQQ	522	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KSGQQ	522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85389
...KSGQQ	522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85388
...KSGQQ	522	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85387
...KSGQQ	522		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KSGQQ	522		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)