TopFIND 4.0

Q9BQ50: Three prime repair exonuclease 2

General Information

Protein names
- Three prime repair exonuclease 2
- 3.1.11.2
- 3'-5' exonuclease TREX2
Gene names TREX2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BQ50

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGRAGSPLPR SSWPRMDDCG SRSRCSPTLC SSLRTCYPRG NITMSEAPRA ETFVFLDLEA 
        70         80         90        100        110        120 
TGLPSVEPEI AELSLFAVHR SSLENPEHDE SGALVLPRVL DKLTLCMCPE RPFTAKASEI 
       130        140        150        160        170        180 
TGLSSEGLAR CRKAGFDGAV VRTLQAFLSR QAGPICLVAH NGFDYDFPLL CAELRRLGAR 
       190        200        210        220        230        240 
LPRDTVCLDT LPALRGLDRA HSHGTRARGR QGYSLGSLFH RYFRAEPSAA HSAEGDVHTL 
       250        260        270    
LLIFLHRAAE LLAWADEQAR GWAHIEPMYL PPDDPSLEA

Isoforms

- Isoform 2 of Three prime repair exonuclease 2

Sequence View

        10         20         30         40         50         60 
MGRAGSPLPR SSWPRMDDCG SRSRCSPTLC SSLRTCYPRG NITMSEAPRA ETFVFLDLEA 
        70         80         90        100        110        120 
TGLPSVEPEI AELSLFAVHR SSLENPEHDE SGALVLPRVL DKLTLCMCPE RPFTAKASEI 
       130        140        150        160        170        180 
TGLSSEGLAR CRKAGFDGAV VRTLQAFLSR QAGPICLVAH NGFDYDFPLL CAELRRLGAR 
       190        200        210        220        230        240 
LPRDTVCLDT LPALRGLDRA HSHGTRARGR QGYSLGSLFH RYFRAEPSAA HSAEGDVHTL 
       250        260        270    
LLIFLHRAAE LLAWADEQAR GWAHIEPMYL PPDDPSLEA



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BQ50-1-unknown MGRAGS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BQ50-44-unknown MSEAPR... 44 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92982

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PSLEA 279 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PSLEA 279 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88600

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)