TopFIND 4.0

Q9BQB6: Vitamin K epoxide reductase complex subunit 1

General Information

Protein names
- Vitamin K epoxide reductase complex subunit 1
- 1.17.4.4 {ECO:0000269|PubMed:15879509, ECO:0000269|PubMed:16270630, ECO:0000269|PubMed:20978134, ECO:0000269|PubMed:22923610}
- Vitamin K1 2,3-epoxide reductase subunit 1
Gene names VKORC1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BQB6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGSTWGSPGW VRLALCLTGL VLSLYALHVK AARARDRDYR ALCDVGTAIS CSRVFSSRWG 
        70         80         90        100        110        120 
RGFGLVEHVL GQDSILNQSN SIFGCIFYTL QLLLGCLRTR WASVLMLLSS LVSLAGSVYL 
       130        140        150        160    
AWILFFVLYD FCIVCITTYA INVSLMWLSF RKVQEPQGKA KRH

Isoforms

- Isoform 2 of Vitamin K epoxide reductase complex subunit 1 - Isoform 3 of Vitamin K epoxide reductase complex subunit 1

Sequence View

        10         20         30         40         50         60 
MGSTWGSPGW VRLALCLTGL VLSLYALHVK AARARDRDYR ALCDVGTAIS CSRVFSSRWG 
        70         80         90        100        110        120 
RGFGLVEHVL GQDSILNQSN SIFGCIFYTL QLLLGCLRTR WASVLMLLSS LVSLAGSVYL 
       130        140        150        160    
AWILFFVLYD FCIVCITTYA INVSLMWLSF RKVQEPQGKA KRH         10         20         30         40         50         60 
MGSTWGSPGW VRLALCLTGL VLSLYALHVK AARARDRDYR ALCDVGTAIS CSRVFSSRWG 
        70         80         90        100        110        120 
RGFGLVEHVL GQDSILNQSN SIFGCIFYTL QLLLGCLRTR WASVLMLLSS LVSLAGSVYL 
       130        140        150        160    
AWILFFVLYD FCIVCITTYA INVSLMWLSF RKVQEPQGKA KRH



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BQB6-1-unknown MGSTWG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BQB6-1-unknown MGSTWG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94193
    Q9BQB6-1-unknown MGSTWG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94194

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KAKRH 163 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)