Q9BQS8: FYVE and coiled-coil domain-containing protein 1
| Protein names | - FYVE and coiled-coil domain-containing protein 1 - Zinc finger FYVE domain-containing protein 7 |
|---|---|
| Gene names | FYCO1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9BQS8 |
4
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK
70 80 90 100 110 120
ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT
130 140 150 160 170 180
LQQCFMNTKV TSDWYYARSP FLQPKLSSDI VGQLYELTEV QFDLASRGFD LDAAWPTFAR
190 200 210 220 230 240
RTLTTGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD
250 260 270 280 290 300
QLEVREKQLR ERMQQLDREN QELRAAVSQQ GEQLQTERER GRTAAEDNVR LTCLVAELQK
310 320 330 340 350 360
QWEVTQATQN TVKELQTCLQ GLELGAAEKE EDYHTALRRL ESMLQPLAQE LEATRDSLDK
370 380 390 400 410 420
KNQHLASFPG WLAMAQQKAD TASDTKGRQE PIPSDAAQEM QELGEKLQAL ERERTKVEEV
430 440 450 460 470 480
NRQQSAQLEQ LVKELQLKED ARASLERLVK EMAPLQEELS GKGQEADQLW RRLQELLAHT
490 500 510 520 530 540
SSWEEELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI
550 560 570 580 590 600
QDKDHLSQQV GMLERLAGPP GPELPVAGEK NEALVPVNSS LQEAWGKPEE EQRGLQEAQL
610 620 630 640 650 660
DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QRESAIQGSL
670 680 690 700 710 720
ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAQMAEKEA ILQSKEGECQ QLREEVEQCQ
730 740 750 760 770 780
QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPT DNEARELAAQ LALSQAQLEV
790 800 810 820 830 840
HQGEVQRLQA QVVDLQAKMR AALDDQDKVQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA
850 860 870 880 890 900
HVQELLQCSE REGALQEERA DEAQQREEEL RALQEELSQA KCSSEEAQLE HAELQEQLHR
910 920 930 940 950 960
ANTDTAELGI QVCALTVEKE RVEEALACAV QELQDAKEAA SREREGLERQ VAGLQQEKES
970 980 990 1000 1010 1020
LQEKLKAAKA AAGSLPGLQA QLAQAEQRAQ SLQEAAHQEL NTLKFQLSAE IMDYQSRLKN
1030 1040 1050 1060 1070 1080
AGEECKSLRG QLEEQGRQLQ AAEEAVEKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE
1090 1100 1110 1120 1130 1140
GAALREDLER TQKELEKATT KIQEYYNKLC QEVTNRERND QKMLADLDDL NRTKKYLEER
1150 1160 1170 1180 1190 1200
LIELLRDKDA LWQKSDALEF QQKLSAEERW LGDTEANHCL DCKREFSWMV RRHHCRICGR
1210 1220 1230 1240 1250 1260
IFCYYCCNNY VLSKHGGKKE RCCRACFQKL SEGPGSPDSS GSGTSQGEPS PALSPASPGP
1270 1280 1290 1300 1310 1320
QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NAAEQDTTST
1330 1340 1350 1360 1370 1380
SLTPEDTEDM PVGQDSEICL LKSGELMIKV PLTVDEIASF GEGSRELFVR SSTYSLIPIT
1390 1400 1410 1420 1430 1440
VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI PTTRCNSHKE NIQGQLKVRT
1450 1460 1470
PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL
Isoforms
- Isoform 2 of FYVE and coiled-coil domain-containing protein 1 - Isoform 3 of FYVE and coiled-coil domain-containing protein 1 - Isoform 4 of FYVE and coiled-coil domain-containing protein 1Sequence View
10 20 30 40 50 60
MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK
70 80 90 100 110 120
ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT
130 140 150 160 170 180
LQQCFMNTKV TSDWYYARSP FLQPKLSSDI VGQLYELTEV QFDLASRGFD LDAAWPTFAR
190 200 210 220 230 240
RTLTTGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD
250 260 270 280 290 300
QLEVREKQLR ERMQQLDREN QELRAAVSQQ GEQLQTERER GRTAAEDNVR LTCLVAELQK
310 320 330 340 350 360
QWEVTQATQN TVKELQTCLQ GLELGAAEKE EDYHTALRRL ESMLQPLAQE LEATRDSLDK
370 380 390 400 410 420
KNQHLASFPG WLAMAQQKAD TASDTKGRQE PIPSDAAQEM QELGEKLQAL ERERTKVEEV
430 440 450 460 470 480
NRQQSAQLEQ LVKELQLKED ARASLERLVK EMAPLQEELS GKGQEADQLW RRLQELLAHT
490 500 510 520 530 540
SSWEEELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI
550 560 570 580 590 600
QDKDHLSQQV GMLERLAGPP GPELPVAGEK NEALVPVNSS LQEAWGKPEE EQRGLQEAQL
610 620 630 640 650 660
DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QRESAIQGSL
670 680 690 700 710 720
ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAQMAEKEA ILQSKEGECQ QLREEVEQCQ
730 740 750 760 770 780
QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPT DNEARELAAQ LALSQAQLEV
790 800 810 820 830 840
HQGEVQRLQA QVVDLQAKMR AALDDQDKVQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA
850 860 870 880 890 900
HVQELLQCSE REGALQEERA DEAQQREEEL RALQEELSQA KCSSEEAQLE HAELQEQLHR
910 920 930 940 950 960
ANTDTAELGI QVCALTVEKE RVEEALACAV QELQDAKEAA SREREGLERQ VAGLQQEKES
970 980 990 1000 1010 1020
LQEKLKAAKA AAGSLPGLQA QLAQAEQRAQ SLQEAAHQEL NTLKFQLSAE IMDYQSRLKN
1030 1040 1050 1060 1070 1080
AGEECKSLRG QLEEQGRQLQ AAEEAVEKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE
1090 1100 1110 1120 1130 1140
GAALREDLER TQKELEKATT KIQEYYNKLC QEVTNRERND QKMLADLDDL NRTKKYLEER
1150 1160 1170 1180 1190 1200
LIELLRDKDA LWQKSDALEF QQKLSAEERW LGDTEANHCL DCKREFSWMV RRHHCRICGR
1210 1220 1230 1240 1250 1260
IFCYYCCNNY VLSKHGGKKE RCCRACFQKL SEGPGSPDSS GSGTSQGEPS PALSPASPGP
1270 1280 1290 1300 1310 1320
QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NAAEQDTTST
1330 1340 1350 1360 1370 1380
SLTPEDTEDM PVGQDSEICL LKSGELMIKV PLTVDEIASF GEGSRELFVR SSTYSLIPIT
1390 1400 1410 1420 1430 1440
VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI PTTRCNSHKE NIQGQLKVRT
1450 1460 1470
PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL
10 20 30 40 50 60
MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK
70 80 90 100 110 120
ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT
130 140 150 160 170 180
LQQCFMNTKV TSDWYYARSP FLQPKLSSDI VGQLYELTEV QFDLASRGFD LDAAWPTFAR
190 200 210 220 230 240
RTLTTGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD
250 260 270 280 290 300
QLEVREKQLR ERMQQLDREN QELRAAVSQQ GEQLQTERER GRTAAEDNVR LTCLVAELQK
310 320 330 340 350 360
QWEVTQATQN TVKELQTCLQ GLELGAAEKE EDYHTALRRL ESMLQPLAQE LEATRDSLDK
370 380 390 400 410 420
KNQHLASFPG WLAMAQQKAD TASDTKGRQE PIPSDAAQEM QELGEKLQAL ERERTKVEEV
430 440 450 460 470 480
NRQQSAQLEQ LVKELQLKED ARASLERLVK EMAPLQEELS GKGQEADQLW RRLQELLAHT
490 500 510 520 530 540
SSWEEELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI
550 560 570 580 590 600
QDKDHLSQQV GMLERLAGPP GPELPVAGEK NEALVPVNSS LQEAWGKPEE EQRGLQEAQL
610 620 630 640 650 660
DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QRESAIQGSL
670 680 690 700 710 720
ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAQMAEKEA ILQSKEGECQ QLREEVEQCQ
730 740 750 760 770 780
QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPT DNEARELAAQ LALSQAQLEV
790 800 810 820 830 840
HQGEVQRLQA QVVDLQAKMR AALDDQDKVQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA
850 860 870 880 890 900
HVQELLQCSE REGALQEERA DEAQQREEEL RALQEELSQA KCSSEEAQLE HAELQEQLHR
910 920 930 940 950 960
ANTDTAELGI QVCALTVEKE RVEEALACAV QELQDAKEAA SREREGLERQ VAGLQQEKES
970 980 990 1000 1010 1020
LQEKLKAAKA AAGSLPGLQA QLAQAEQRAQ SLQEAAHQEL NTLKFQLSAE IMDYQSRLKN
1030 1040 1050 1060 1070 1080
AGEECKSLRG QLEEQGRQLQ AAEEAVEKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE
1090 1100 1110 1120 1130 1140
GAALREDLER TQKELEKATT KIQEYYNKLC QEVTNRERND QKMLADLDDL NRTKKYLEER
1150 1160 1170 1180 1190 1200
LIELLRDKDA LWQKSDALEF QQKLSAEERW LGDTEANHCL DCKREFSWMV RRHHCRICGR
1210 1220 1230 1240 1250 1260
IFCYYCCNNY VLSKHGGKKE RCCRACFQKL SEGPGSPDSS GSGTSQGEPS PALSPASPGP
1270 1280 1290 1300 1310 1320
QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NAAEQDTTST
1330 1340 1350 1360 1370 1380
SLTPEDTEDM PVGQDSEICL LKSGELMIKV PLTVDEIASF GEGSRELFVR SSTYSLIPIT
1390 1400 1410 1420 1430 1440
VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI PTTRCNSHKE NIQGQLKVRT
1450 1460 1470
PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL
10 20 30 40 50 60
MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK
70 80 90 100 110 120
ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT
130 140 150 160 170 180
LQQCFMNTKV TSDWYYARSP FLQPKLSSDI VGQLYELTEV QFDLASRGFD LDAAWPTFAR
190 200 210 220 230 240
RTLTTGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD
250 260 270 280 290 300
QLEVREKQLR ERMQQLDREN QELRAAVSQQ GEQLQTERER GRTAAEDNVR LTCLVAELQK
310 320 330 340 350 360
QWEVTQATQN TVKELQTCLQ GLELGAAEKE EDYHTALRRL ESMLQPLAQE LEATRDSLDK
370 380 390 400 410 420
KNQHLASFPG WLAMAQQKAD TASDTKGRQE PIPSDAAQEM QELGEKLQAL ERERTKVEEV
430 440 450 460 470 480
NRQQSAQLEQ LVKELQLKED ARASLERLVK EMAPLQEELS GKGQEADQLW RRLQELLAHT
490 500 510 520 530 540
SSWEEELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI
550 560 570 580 590 600
QDKDHLSQQV GMLERLAGPP GPELPVAGEK NEALVPVNSS LQEAWGKPEE EQRGLQEAQL
610 620 630 640 650 660
DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QRESAIQGSL
670 680 690 700 710 720
ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAQMAEKEA ILQSKEGECQ QLREEVEQCQ
730 740 750 760 770 780
QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPT DNEARELAAQ LALSQAQLEV
790 800 810 820 830 840
HQGEVQRLQA QVVDLQAKMR AALDDQDKVQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA
850 860 870 880 890 900
HVQELLQCSE REGALQEERA DEAQQREEEL RALQEELSQA KCSSEEAQLE HAELQEQLHR
910 920 930 940 950 960
ANTDTAELGI QVCALTVEKE RVEEALACAV QELQDAKEAA SREREGLERQ VAGLQQEKES
970 980 990 1000 1010 1020
LQEKLKAAKA AAGSLPGLQA QLAQAEQRAQ SLQEAAHQEL NTLKFQLSAE IMDYQSRLKN
1030 1040 1050 1060 1070 1080
AGEECKSLRG QLEEQGRQLQ AAEEAVEKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE
1090 1100 1110 1120 1130 1140
GAALREDLER TQKELEKATT KIQEYYNKLC QEVTNRERND QKMLADLDDL NRTKKYLEER
1150 1160 1170 1180 1190 1200
LIELLRDKDA LWQKSDALEF QQKLSAEERW LGDTEANHCL DCKREFSWMV RRHHCRICGR
1210 1220 1230 1240 1250 1260
IFCYYCCNNY VLSKHGGKKE RCCRACFQKL SEGPGSPDSS GSGTSQGEPS PALSPASPGP
1270 1280 1290 1300 1310 1320
QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NAAEQDTTST
1330 1340 1350 1360 1370 1380
SLTPEDTEDM PVGQDSEICL LKSGELMIKV PLTVDEIASF GEGSRELFVR SSTYSLIPIT
1390 1400 1410 1420 1430 1440
VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI PTTRCNSHKE NIQGQLKVRT
1450 1460 1470
PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL
Protein Neighborhood
Domains & Features
4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9BQS8-2-unknown | MASTNA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9BQS8-1-unknown | MASTNA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt75609 | |||
| Q9BQS8-1-unknown | MASTNA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt75610 | |||
| Q9BQS8-1-unknown | MASTNA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt75611 | |||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110120 | ||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110121 | ||
| Q9BQS8-2-Acetylation | ASTNAE... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110122 | ||
| Q9BQS8-1330-unknown | MPVGQD... | 1330 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000398517 | |||
| Q9BQS8-1330-unknown | MPVGQD... | 1330 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt200663 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GSDFL | 1478 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GSDFL | 1478 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt71229 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|