TopFIND 4.0

Q9BSA9: Endosomal/lysosomal potassium channel TMEM175 {ECO:0000305}

General Information

Protein names
- Endosomal/lysosomal potassium channel TMEM175 {ECO:0000305}
- Transmembrane protein 175 {ECO:0000312|HGNC:HGNC:28709}
- hTMEM175 {ECO:0000303|PubMed:26317472, ECO:0000303|PubMed:28723891}
Gene names TMEM175
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BSA9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQPRTPEQA LDTPGDCPPG RRDEDAGEGI QCSQRMLSFS DALLSIIATV MILPVTHTEI 
        70         80         90        100        110        120 
SPEQQFDRSV QRLLATRIAV YLMTFLIVTV AWAAHTRLFQ VVGKTDDTLA LLNLACMMTI 
       130        140        150        160        170        180 
TFLPYTFSLM VTFPDVPLGI FLFCVCVIAI GVVQALIVGY AFHFPHLLSP QIQRSAHRAL 
       190        200        210        220        230        240 
YRRHVLGIVL QGPALCFAAA IFSLFFVPLS YLLMVTVILL PYVSKVTGWC RDRLLGHREP 
       250        260        270        280        290        300 
SAHPVEVFSF DLHEPLSKER VEAFSDGVYA IVATLLILDI CEDNVPDPKD VKERFSGSLV 
       310        320        330        340        350        360 
AALSATGPRF LAYFGSFATV GLLWFAHHSL FLHVRKATRA MGLLNTLSLA FVGGLPLAYQ 
       370        380        390        400        410        420 
QTSAFARQPR DELERVRVSC TIIFLASIFQ LAMWTTALLH QAETLQPSVW FGGREHVLMF 
       430        440        450        460        470        480 
AKLALYPCAS LLAFASTCLL SRFSVGIFHL MQIAVPCAFL LLRLLVGLAL ATLRVLRGLA 
       490        500    
RPEHPPPAPT GQDDPQSQLL PAPC

Isoforms

- Isoform 2 of Transmembrane protein 175 - Isoform 2 of Endosomal/lysosomal potassium channel TMEM175

Sequence View

        10         20         30         40         50         60 
MSQPRTPEQA LDTPGDCPPG RRDEDAGEGI QCSQRMLSFS DALLSIIATV MILPVTHTEI 
        70         80         90        100        110        120 
SPEQQFDRSV QRLLATRIAV YLMTFLIVTV AWAAHTRLFQ VVGKTDDTLA LLNLACMMTI 
       130        140        150        160        170        180 
TFLPYTFSLM VTFPDVPLGI FLFCVCVIAI GVVQALIVGY AFHFPHLLSP QIQRSAHRAL 
       190        200        210        220        230        240 
YRRHVLGIVL QGPALCFAAA IFSLFFVPLS YLLMVTVILL PYVSKVTGWC RDRLLGHREP 
       250        260        270        280        290        300 
SAHPVEVFSF DLHEPLSKER VEAFSDGVYA IVATLLILDI CEDNVPDPKD VKERFSGSLV 
       310        320        330        340        350        360 
AALSATGPRF LAYFGSFATV GLLWFAHHSL FLHVRKATRA MGLLNTLSLA FVGGLPLAYQ 
       370        380        390        400        410        420 
QTSAFARQPR DELERVRVSC TIIFLASIFQ LAMWTTALLH QAETLQPSVW FGGREHVLMF 
       430        440        450        460        470        480 
AKLALYPCAS LLAFASTCLL SRFSVGIFHL MQIAVPCAFL LLRLLVGLAL ATLRVLRGLA 
       490        500    
RPEHPPPAPT GQDDPQSQLL PAPC         10         20         30         40         50         60 
MSQPRTPEQA LDTPGDCPPG RRDEDAGEGI QCSQRMLSFS DALLSIIATV MILPVTHTEI 
        70         80         90        100        110        120 
SPEQQFDRSV QRLLATRIAV YLMTFLIVTV AWAAHTRLFQ VVGKTDDTLA LLNLACMMTI 
       130        140        150        160        170        180 
TFLPYTFSLM VTFPDVPLGI FLFCVCVIAI GVVQALIVGY AFHFPHLLSP QIQRSAHRAL 
       190        200        210        220        230        240 
YRRHVLGIVL QGPALCFAAA IFSLFFVPLS YLLMVTVILL PYVSKVTGWC RDRLLGHREP 
       250        260        270        280        290        300 
SAHPVEVFSF DLHEPLSKER VEAFSDGVYA IVATLLILDI CEDNVPDPKD VKERFSGSLV 
       310        320        330        340        350        360 
AALSATGPRF LAYFGSFATV GLLWFAHHSL FLHVRKATRA MGLLNTLSLA FVGGLPLAYQ 
       370        380        390        400        410        420 
QTSAFARQPR DELERVRVSC TIIFLASIFQ LAMWTTALLH QAETLQPSVW FGGREHVLMF 
       430        440        450        460        470        480 
AKLALYPCAS LLAFASTCLL SRFSVGIFHL MQIAVPCAFL LLRLLVGLAL ATLRVLRGLA 
       490        500    
RPEHPPPAPT GQDDPQSQLL PAPC



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BSA9-1-unknown MSQPRT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BSA9-117-unknown MMTITF... 117 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92320

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LPAPC 504 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LPAPC 504 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87938

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)