TopFIND 4.0

Q9BUN8: Derlin-1 {ECO:0000303|PubMed:15215855}

General Information

Protein names
- Derlin-1 {ECO:0000303|PubMed:15215855}
- Degradation in endoplasmic reticulum protein 1
- DERtrin-1
- Der1-like protein 1 {ECO:0000303|PubMed:15215855}
Gene names DERL1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BUN8

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSDIGDWFRS IPAITRYWFA ATVAVPLVGK LGLISPAYLF LWPEAFLYRF QIWRPITATF 
        70         80         90        100        110        120 
YFPVGPGTGF LYLVNLYFLY QYSTRLETGA FDGRPADYLF MLLFNWICIV ITGLAMDMQL 
       130        140        150        160        170        180 
LMIPLIMSVL YVWAQLNRDM IVSFWFGTRF KACYLPWVIL GFNYIIGGSV INELIGNLVG 
       190        200        210        220        230        240 
HLYFFLMFRY PMDLGGRNFL STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH 
       250    
NWGQGFRLGD Q

Isoforms

- Isoform 2 of Derlin-1

Sequence View

        10         20         30         40         50         60 
MSDIGDWFRS IPAITRYWFA ATVAVPLVGK LGLISPAYLF LWPEAFLYRF QIWRPITATF 
        70         80         90        100        110        120 
YFPVGPGTGF LYLVNLYFLY QYSTRLETGA FDGRPADYLF MLLFNWICIV ITGLAMDMQL 
       130        140        150        160        170        180 
LMIPLIMSVL YVWAQLNRDM IVSFWFGTRF KACYLPWVIL GFNYIIGGSV INELIGNLVG 
       190        200        210        220        230        240 
HLYFFLMFRY PMDLGGRNFL STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH 
       250    
NWGQGFRLGD Q



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BUN8-1-unknown MSDIGD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72640
    Q9BUN8-2-unknown MSDIGD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BUN8-2-Acetylation SDIGDW... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BUN8-2-Acetylation SDIGDW... 2 acetylation- other CNRS/ISV Large_scale_NTA_Human
    Q9BUN8-2-Acetylation SDIGDW... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111447

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLGDQ 251 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RLGDQ 251 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68258

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)