Q9BUZ4: TNF receptor-associated factor 4

General Information

Protein names	- TNF receptor-associated factor 4 - Cysteine-rich domain associated with RING and Traf domains protein 1 - Metastatic lymph node gene 62 protein - MLN 62 - RING finger protein 83
Gene names	TRAF4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BUZ4

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP
        70         80         90        100        110        120
LDYAKIYPDP ELEVQVLGLP IRCIHSEEGC RWSGPLRHLQ GHLNTCSFNV IPCPNRCPMK
       130        140        150        160        170        180
LSRRDLPAHL QHDCPKRRLK CEFCGCDFSG EAYESHEGMC PQESVYCENK CGARMMRRLL
       190        200        210        220        230        240
AQHATSECPK RTQPCTYCTK EFVFDTIQSH QYQCPRLPVA CPNQCGVGTV AREDLPGHLK
       250        260        270        280        290        300
DSCNTALVLC PFKDSGCKHR CPKLAMARHV EESVKPHLAM MCALVSRQRQ ELQELRRELE
       310        320        330        340        350        360
ELSVGSDGVL IWKIGSYGRR LQEAKAKPNL ECFSPAFYTH KYGYKLQVSA FLNGNGSGEG
       370        380        390        400        410        420
THLSLYIRVL PGAFDNLLEW PFARRVTFSL LDQSDPGLAK PQHVTETFHP DPNWKNFQKP
       430        440        450        460        470
GTWRGSLDES SLGFGYPKFI SHQDIRKRNY VRDDAVFIRA AVELPRKILS

Isoforms

- Isoform 2 of TNF receptor-associated factor 4

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9BUZ4-1-unknown	MPGFDY...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9BUZ4-1-unknown	MPGFDY...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92947
Q9BUZ4-119-unknown	MKLSRR...	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465164
Q9BUZ4-119-unknown	MKLSRR...	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468107
Q9BUZ4-119-unknown	MKLSRR...	119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197213

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QESVYC	166	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465164
...CGARMM	175	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415789
...FDTIQS	208	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000468107
...RKILS	470	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RKILS	470	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88565

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)