TopFIND 4.0

Q9BXY4: R-spondin-3

General Information

Protein names
- R-spondin-3
- Protein with TSP type-1 repeat
- hPWTSR
- Roof plate-specific spondin-3
- hRspo3
- Thrombospondin type-1 domain-containing protein 2
Gene names RSPO3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BXY4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHLRLISWLF IILNFMEYIG SQNASRGRRQ RRMHPNVSQG CQGGCATCSD YNGCLSCKPR 
        70         80         90        100        110        120 
LFFALERIGM KQIGVCLSSC PSGYYGTRYP DINKCTKCKA DCDTCFNKNF CTKCKSGFYL 
       130        140        150        160        170        180 
HLGKCLDNCP EGLEANNHTM ECVSIVHCEV SEWNPWSPCT KKGKTCGFKR GTETRVREII 
       190        200        210        220        230        240 
QHPSAKGNLC PPTNETRKCT VQRKKCQKGE RGKKGRERKR KKPNKGESKE AIPDSKSLES 
       250        260        270    
SKEIPEQREN KQQQKKRKVQ DKQKSVSVST VH

Isoforms

- Isoform 2 of R-spondin-3

Sequence View

        10         20         30         40         50         60 
MHLRLISWLF IILNFMEYIG SQNASRGRRQ RRMHPNVSQG CQGGCATCSD YNGCLSCKPR 
        70         80         90        100        110        120 
LFFALERIGM KQIGVCLSSC PSGYYGTRYP DINKCTKCKA DCDTCFNKNF CTKCKSGFYL 
       130        140        150        160        170        180 
HLGKCLDNCP EGLEANNHTM ECVSIVHCEV SEWNPWSPCT KKGKTCGFKR GTETRVREII 
       190        200        210        220        230        240 
QHPSAKGNLC PPTNETRKCT VQRKKCQKGE RGKKGRERKR KKPNKGESKE AIPDSKSLES 
       250        260        270    
SKEIPEQREN KQQQKKRKVQ DKQKSVSVST VH



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BXY4-1-unknown MHLRLI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88284
    Q9BXY4-22-unknown QNASRG... 22 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BXY4-22-unknown QNASRG... 22 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113066

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VSTVH 272 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)