TopFIND 4.0

Q9BYC5: Alpha-(1,6)-fucosyltransferase

General Information

Protein names
- Alpha-(1,6)-fucosyltransferase
- Alpha1-6FucT
- 2.4.1.68
- Fucosyltransferase 8
- GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase
- GDP-fucose--glycoprotein fucosyltransferase
- Glycoprotein 6-alpha-L-fucosyltransferase
Gene names FUT8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BYC5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL 
        70         80         90        100        110        120 
RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGK DHEILRRRIE 
       130        140        150        160        170        180 
NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR 
       190        200        210        220        230        240 
EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT 
       250        260        270        280        290        300 
LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR 
       310        320        330        340        350        360 
PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI 
       370        380        390        400        410        420 
GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK 
       430        440        450        460        470        480 
YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ 
       490        500        510        520        530        540 
TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWDGYS 
       550        560        570    
KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK

Isoforms

- Isoform 2 of Alpha-(1,6)-fucosyltransferase - Isoform 3 of Alpha-(1,6)-fucosyltransferase - Isoform 4 of Alpha-(1,6)-fucosyltransferase

Sequence View

        10         20         30         40         50         60 
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL 
        70         80         90        100        110        120 
RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGK DHEILRRRIE 
       130        140        150        160        170        180 
NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR 
       190        200        210        220        230        240 
EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT 
       250        260        270        280        290        300 
LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR 
       310        320        330        340        350        360 
PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI 
       370        380        390        400        410        420 
GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK 
       430        440        450        460        470        480 
YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ 
       490        500        510        520        530        540 
TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWDGYS 
       550        560        570    
KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK         10         20         30         40         50         60 
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL 
        70         80         90        100        110        120 
RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGK DHEILRRRIE 
       130        140        150        160        170        180 
NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR 
       190        200        210        220        230        240 
EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT 
       250        260        270        280        290        300 
LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR 
       310        320        330        340        350        360 
PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI 
       370        380        390        400        410        420 
GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK 
       430        440        450        460        470        480 
YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ 
       490        500        510        520        530        540 
TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWDGYS 
       550        560        570    
KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK         10         20         30         40         50         60 
MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL 
        70         80         90        100        110        120 
RRMAESLRIP EGPIDQGPAI GRVRVLEEQL VKAKEQIENY KKQTRNGLGK DHEILRRRIE 
       130        140        150        160        170        180 
NGAKELWFFL QSELKKLKNL EGNELQRHAD EFLLDLGHHE RSIMTDLYYL SQTDGAGDWR 
       190        200        210        220        230        240 
EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT 
       250        260        270        280        290        300 
LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR 
       310        320        330        340        350        360 
PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFKHPVI 
       370        380        390        400        410        420 
GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK 
       430        440        450        460        470        480 
YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ 
       490        500        510        520        530        540 
TLHPDASANF HSLDDIYYFG GQNAHNQIAI YAHQPRTADE IPMEPGDIIG VAGNHWDGYS 
       550        560        570    
KGVNRKLGRT GLYPSYKVRE KIETVKYPTY PEAEK



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Directness:


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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BYC5-1-unknown MRPWTG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9BYC5-1-unknown MRPWTG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75556
    Q9BYC5-164-unknown MTDLYY... 164 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75557
    Q9BYC5-164-unknown MTDLYY... 164 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt97946

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)