Q9BZ67: FERM domain-containing protein 8

General Information

Protein names	- FERM domain-containing protein 8 - Band4.1 inhibitor LRP interactor {ECO:0000303\|PubMed:19572019} - Bili {ECO:0000303\|PubMed:19572019} - iRhom tail-associated protein {ECO:0000303\|PubMed:29897333} - iTAP {ECO:0000303\|PubMed:29897333}
Gene names	FRMD8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BZ67

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of FERM domain-containing protein 8 - Isoform 3 of FERM domain-containing protein 8

Sequence View

        10         20         30         40         50         60
MDGTEGSAGQ PGPAERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLSAHELHRA
        70         80         90        100        110        120
VREVLQLPDI ALDVFALWLV SPLLEVQLKP KHQPYKLGRQ WPELLLRFTS APDDDVAMDE
       130        140        150        160        170        180
PFLQFRRNVF FPKRRELQIH DEEVLRLLYE EAKGNVLAAR YPCDVEDCEA LGALVCRVQL
       190        200        210        220        230        240
GPYQPGRPAA CDLREKLDSF LPAHLCKRGQ SLFAALRGRG ARAGPGEQGL LNAYRQVQEV
       250        260        270        280        290        300
SSDGGCEAAL GTHYRAYLLK CHELPFYGCA FFHGEVDKPA QGFLHRGGRK PVSVAISLEG
       310        320        330        340        350        360
VHVIDSREKH VLLGLRFQEL SWDHTSPEEE EPILWLEFDG DSEGTPVNKL LKIYSKQAEL
       370        380        390        400        410        420
MSSLIEYCIE LSQAAEPAGP QDSATGSPSD PSSSLAPVQR PKLRRQGSVV SSRIQHLSTI
       430        440        450        460
DYVEDGKGIR RVKPKRTTSF FSRQLSLGQG SYTVVQPGDS LEQG         10         20         30         40         50         60
MDGTEGSAGQ PGPAERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLSAHELHRA
        70         80         90        100        110        120
VREVLQLPDI ALDVFALWLV SPLLEVQLKP KHQPYKLGRQ WPELLLRFTS APDDDVAMDE
       130        140        150        160        170        180
PFLQFRRNVF FPKRRELQIH DEEVLRLLYE EAKGNVLAAR YPCDVEDCEA LGALVCRVQL
       190        200        210        220        230        240
GPYQPGRPAA CDLREKLDSF LPAHLCKRGQ SLFAALRGRG ARAGPGEQGL LNAYRQVQEV
       250        260        270        280        290        300
SSDGGCEAAL GTHYRAYLLK CHELPFYGCA FFHGEVDKPA QGFLHRGGRK PVSVAISLEG
       310        320        330        340        350        360
VHVIDSREKH VLLGLRFQEL SWDHTSPEEE EPILWLEFDG DSEGTPVNKL LKIYSKQAEL
       370        380        390        400        410        420
MSSLIEYCIE LSQAAEPAGP QDSATGSPSD PSSSLAPVQR PKLRRQGSVV SSRIQHLSTI
       430        440        450        460
DYVEDGKGIR RVKPKRTTSF FSRQLSLGQG SYTVVQPGDS LEQG

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BZ67-1-unknown	MDGTEG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75479
Q9BZ67-1-Acetylation	MDGTEG...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BZ67-1-Acetylation	MDGTEG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9BZ67-1-Acetylation	MDGTEG...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BZ67-1-Acetylation	MDGTEG...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105485

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SLEQG	464	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...SLEQG	464	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt71097

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)