TopFIND 4.0

Q9BZR9: E3 ubiquitin-protein ligase TRIM8

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM8
- 2.3.2.27
- Glioblastoma-expressed RING finger protein
- RING finger protein 27
- RING-type E3 ubiquitin transferase TRIM8 {ECO:0000305}
- Tripartite motif-containing protein 8
Gene names TRIM8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9BZR9

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKDSGLV RCPECNQAYN 
        70         80         90        100        110        120 
QKPGLEKNLK LTNIVEKFNA LHVEKPPAAL HCVFCRRGPP LPAQKVCLRC EAPCCQSHVQ 
       130        140        150        160        170        180 
THLQQPSTAR GHLLVEADDV RAWSCPQHNA YRLYHCEAEQ VAVCQYCCYY SGAHQGHSVC 
       190        200        210        220        230        240 
DVEIRRNEIR KMLMKQQDRL EEREQDIEDQ LYKLESDKRL VEEKVNQLKE EVRLQYEKLH 
       250        260        270        280        290        300 
QLLDEDLRQT VEVLDKAQAK FCSENAAQAL HLGERMQEAK KLLGSLQLLF DKTEDVSFMK 
       310        320        330        340        350        360 
NTKSVKILMD RTQTCTSSSL SPTKIGHLNS KLFLNEVAKK EKQLRKMLEG PFSTPVPFLQ 
       370        380        390        400        410        420 
SVPLYPCGVS SSGAEKRKHS TAFPEASFLE TSSGPVGGQY GAAGTASGEG QSGQPLGPCS 
       430        440        450        460        470        480 
STQHLVALPG GAQPVHSSPV FPPSQYPNGS AAQQPMLPQY GGRKILVCSV DNCYCSSVAN 
       490        500        510        520        530        540 
HGGHQPYPRS GHFPWTVPSQ EYSHPLPPTP SVPQSLPSLA VRDWLDASQQ PGHQDFYRVY 
       550    
GQPSTKHYVT S

Isoforms



Sequence View



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9BZR9-1-unknown MAENWK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)