Q9C035: Tripartite motif-containing protein 5

General Information

Protein names	- Tripartite motif-containing protein 5 - 2.3.2.27 - RING finger protein 88 - RING-type E3 ubiquitin transferase TRIM5 {ECO:0000305}
Gene names	TRIM5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9C035

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Beta of Tripartite motif-containing protein 5 - Isoform Gamma of Tripartite motif-containing protein 5 - Isoform Delta of Tripartite motif-containing protein 5 - Isoform Epsilon of Tripartite motif-containing protein 5 - Isoform Iota of Tripartite motif-containing protein 5

Sequence View

        10         20         30         40         50         60
MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI
        70         80         90        100        110        120
SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS
       130        140        150        160        170        180
QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN
       190        200        210        220        230        240
VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ
       250        260        270        280        290        300
GSVMELLQGV DGVIKRTENV TLKKPETFPK NQRRVFRAPD LKGMLEVFRE LTDVRRYWVD
       310        320        330        340        350        360
VTVAPNNISC AVISEDKRQV SSPKPQIIYG ARGTRYQTFV NFNYCTGILG SQSITSGKHY
       370        380        390        400        410        420
WEVDVSKKTA WILGVCAGFQ PDAMCNIEKN ENYQPKYGYW VIGLEEGVKC SAFQDSSFHT
       430        440        450        460        470        480
PSVPFIVPLS VIICPDRVGV FLDYEACTVS FFNITNHGFL IYKFSHCSFS QPVFPYLNPR
       490
KCGVPMTLCS PSS         10         20         30         40         50         60
MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI
        70         80         90        100        110        120
SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS
       130        140        150        160        170        180
QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN
       190        200        210        220        230        240
VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ
       250        260        270        280        290        300
GSVMELLQGV DGVIKRTENV TLKKPETFPK NQRRVFRAPD LKGMLEVFRE LTDVRRYWVD
       310        320        330        340        350        360
VTVAPNNISC AVISEDKRQV SSPKPQIIYG ARGTRYQTFV NFNYCTGILG SQSITSGKHY
       370        380        390        400        410        420
WEVDVSKKTA WILGVCAGFQ PDAMCNIEKN ENYQPKYGYW VIGLEEGVKC SAFQDSSFHT
       430        440        450        460        470        480
PSVPFIVPLS VIICPDRVGV FLDYEACTVS FFNITNHGFL IYKFSHCSFS QPVFPYLNPR
       490
KCGVPMTLCS PSS         10         20         30         40         50         60
MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI
        70         80         90        100        110        120
SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS
       130        140        150        160        170        180
QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN
       190        200        210        220        230        240
VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ
       250        260        270        280        290        300
GSVMELLQGV DGVIKRTENV TLKKPETFPK NQRRVFRAPD LKGMLEVFRE LTDVRRYWVD
       310        320        330        340        350        360
VTVAPNNISC AVISEDKRQV SSPKPQIIYG ARGTRYQTFV NFNYCTGILG SQSITSGKHY
       370        380        390        400        410        420
WEVDVSKKTA WILGVCAGFQ PDAMCNIEKN ENYQPKYGYW VIGLEEGVKC SAFQDSSFHT
       430        440        450        460        470        480
PSVPFIVPLS VIICPDRVGV FLDYEACTVS FFNITNHGFL IYKFSHCSFS QPVFPYLNPR
       490
KCGVPMTLCS PSS         10         20         30         40         50         60
MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI
        70         80         90        100        110        120
SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS
       130        140        150        160        170        180
QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN
       190        200        210        220        230        240
VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ
       250        260        270        280        290        300
GSVMELLQGV DGVIKRTENV TLKKPETFPK NQRRVFRAPD LKGMLEVFRE LTDVRRYWVD
       310        320        330        340        350        360
VTVAPNNISC AVISEDKRQV SSPKPQIIYG ARGTRYQTFV NFNYCTGILG SQSITSGKHY
       370        380        390        400        410        420
WEVDVSKKTA WILGVCAGFQ PDAMCNIEKN ENYQPKYGYW VIGLEEGVKC SAFQDSSFHT
       430        440        450        460        470        480
PSVPFIVPLS VIICPDRVGV FLDYEACTVS FFNITNHGFL IYKFSHCSFS QPVFPYLNPR
       490
KCGVPMTLCS PSS         10         20         30         40         50         60
MASGILVNVK EEVTCPICLE LLTQPLSLDC GHSFCQACLT ANHKKSMLDK GESSCPVCRI
        70         80         90        100        110        120
SYQPENIRPN RHVANIVEKL REVKLSPEGQ KVDHCARHGE KLLLFCQEDG KVICWLCERS
       130        140        150        160        170        180
QEHRGHHTFL TEEVAREYQV KLQAALEMLR QKQQEAEELE ADIREEKASW KTQIQYDKTN
       190        200        210        220        230        240
VLADFEQLRD ILDWEESNEL QNLEKEEEDI LKSLTNSETE MVQQTQSLRE LISDLEHRLQ
       250        260        270        280        290        300
GSVMELLQGV DGVIKRTENV TLKKPETFPK NQRRVFRAPD LKGMLEVFRE LTDVRRYWVD
       310        320        330        340        350        360
VTVAPNNISC AVISEDKRQV SSPKPQIIYG ARGTRYQTFV NFNYCTGILG SQSITSGKHY
       370        380        390        400        410        420
WEVDVSKKTA WILGVCAGFQ PDAMCNIEKN ENYQPKYGYW VIGLEEGVKC SAFQDSSFHT
       430        440        450        460        470        480
PSVPFIVPLS VIICPDRVGV FLDYEACTVS FFNITNHGFL IYKFSHCSFS QPVFPYLNPR
       490
KCGVPMTLCS PSS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q9C035-1-unknown	MASGIL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93065
Q9C035-1-unknown	MASGIL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93066
Q9C035-1-unknown	MASGIL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93067
Q9C035-1-unknown	MASGIL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93068
Q9C035-1-unknown	MASGIL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93069
Q9C035-2-unknown	MASGIL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9C035-2-Acetylation	ASGILV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111312
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111313
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111314
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111315
Q9C035-2-Acetylation	ASGILV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111316

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...CSPSS	493	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)