TopFIND 4.0

Q9C037: E3 ubiquitin-protein ligase TRIM4

General Information

Protein names
- E3 ubiquitin-protein ligase TRIM4
- 2.3.2.27
- RING finger protein 87
- RING-type E3 ubiquitin transferase TRIM4 {ECO:0000305}
- Tripartite motif-containing protein 4
Gene names TRIM4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9C037

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEAEDIQEEL TCPICLDYFQ DPVSIECGHN FCRGCLHRNW APGGGPFPCP ECRHPSAPAA 
        70         80         90        100        110        120 
LRPNWALARL TEKTQRRRLG PVPPGLCGRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 
       130        140        150        160        170        180 
APIDEAFESY RTGNFDIHVD EWKRRLIRLL LYHFKQEEKL LKSQRNLVAK MKKVMHLQDV 
       190        200        210        220        230        240 
EVKNATQWKD KIKSQRMRIS TEFSKLHNFL VEEEDLFLQR LNKEEEETKK KLNENTLKLN 
       250        260        270        280        290        300 
QTIASLKKLI LEVGEKSQAP TLELLQNPKE VLTRSEIQDV NYSLEAVKVK TVCQIPLMKE 
       310        320        330        340        350        360 
MLKRFQVAVN LAEDTAHPKL VFSQEGRYVK NTASASSWPV FSSAWNYFAG WRNPQKTAFV 
       370        380        390        400        410        420 
ERFQHLPCVL GKNVFTSGKH YWEVESRDSL EVAVGVCRED VMGITDRSKM SPDVGIWAIY 
       430        440        450        460        470        480 
WSAAGYWPLI GFPGTPTQQE PALHRVGVYL DRGTGNVSFY SAVDGVHLHT FSCSSVSRLR 
       490        500    
PFFWLSPLAS LVIPPVTDRK 

Isoforms

- Isoform Beta of Tripartite motif-containing protein 4 - Isoform Gamma of Tripartite motif-containing protein 4 - Isoform Beta of E3 ubiquitin-protein ligase TRIM4 - Isoform Gamma of E3 ubiquitin-protein ligase TRIM4

Sequence View

        10         20         30         40         50         60 
MEAEDIQEEL TCPICLDYFQ DPVSIECGHN FCRGCLHRNW APGGGPFPCP ECRHPSAPAA 
        70         80         90        100        110        120 
LRPNWALARL TEKTQRRRLG PVPPGLCGRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 
       130        140        150        160        170        180 
APIDEAFESY RTGNFDIHVD EWKRRLIRLL LYHFKQEEKL LKSQRNLVAK MKKVMHLQDV 
       190        200        210        220        230        240 
EVKNATQWKD KIKSQRMRIS TEFSKLHNFL VEEEDLFLQR LNKEEEETKK KLNENTLKLN 
       250        260        270        280        290        300 
QTIASLKKLI LEVGEKSQAP TLELLQNPKE VLTRSEIQDV NYSLEAVKVK TVCQIPLMKE 
       310        320        330        340        350        360 
MLKRFQVAVN LAEDTAHPKL VFSQEGRYVK NTASASSWPV FSSAWNYFAG WRNPQKTAFV 
       370        380        390        400        410        420 
ERFQHLPCVL GKNVFTSGKH YWEVESRDSL EVAVGVCRED VMGITDRSKM SPDVGIWAIY 
       430        440        450        460        470        480 
WSAAGYWPLI GFPGTPTQQE PALHRVGVYL DRGTGNVSFY SAVDGVHLHT FSCSSVSRLR 
       490        500    
PFFWLSPLAS LVIPPVTDRK          10         20         30         40         50         60 
MEAEDIQEEL TCPICLDYFQ DPVSIECGHN FCRGCLHRNW APGGGPFPCP ECRHPSAPAA 
        70         80         90        100        110        120 
LRPNWALARL TEKTQRRRLG PVPPGLCGRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 
       130        140        150        160        170        180 
APIDEAFESY RTGNFDIHVD EWKRRLIRLL LYHFKQEEKL LKSQRNLVAK MKKVMHLQDV 
       190        200        210        220        230        240 
EVKNATQWKD KIKSQRMRIS TEFSKLHNFL VEEEDLFLQR LNKEEEETKK KLNENTLKLN 
       250        260        270        280        290        300 
QTIASLKKLI LEVGEKSQAP TLELLQNPKE VLTRSEIQDV NYSLEAVKVK TVCQIPLMKE 
       310        320        330        340        350        360 
MLKRFQVAVN LAEDTAHPKL VFSQEGRYVK NTASASSWPV FSSAWNYFAG WRNPQKTAFV 
       370        380        390        400        410        420 
ERFQHLPCVL GKNVFTSGKH YWEVESRDSL EVAVGVCRED VMGITDRSKM SPDVGIWAIY 
       430        440        450        460        470        480 
WSAAGYWPLI GFPGTPTQQE PALHRVGVYL DRGTGNVSFY SAVDGVHLHT FSCSSVSRLR 
       490        500    
PFFWLSPLAS LVIPPVTDRK          10         20         30         40         50         60 
MEAEDIQEEL TCPICLDYFQ DPVSIECGHN FCRGCLHRNW APGGGPFPCP ECRHPSAPAA 
        70         80         90        100        110        120 
LRPNWALARL TEKTQRRRLG PVPPGLCGRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 
       130        140        150        160        170        180 
APIDEAFESY RTGNFDIHVD EWKRRLIRLL LYHFKQEEKL LKSQRNLVAK MKKVMHLQDV 
       190        200        210        220        230        240 
EVKNATQWKD KIKSQRMRIS TEFSKLHNFL VEEEDLFLQR LNKEEEETKK KLNENTLKLN 
       250        260        270        280        290        300 
QTIASLKKLI LEVGEKSQAP TLELLQNPKE VLTRSEIQDV NYSLEAVKVK TVCQIPLMKE 
       310        320        330        340        350        360 
MLKRFQVAVN LAEDTAHPKL VFSQEGRYVK NTASASSWPV FSSAWNYFAG WRNPQKTAFV 
       370        380        390        400        410        420 
ERFQHLPCVL GKNVFTSGKH YWEVESRDSL EVAVGVCRED VMGITDRSKM SPDVGIWAIY 
       430        440        450        460        470        480 
WSAAGYWPLI GFPGTPTQQE PALHRVGVYL DRGTGNVSFY SAVDGVHLHT FSCSSVSRLR 
       490        500    
PFFWLSPLAS LVIPPVTDRK          10         20         30         40         50         60 
MEAEDIQEEL TCPICLDYFQ DPVSIECGHN FCRGCLHRNW APGGGPFPCP ECRHPSAPAA 
        70         80         90        100        110        120 
LRPNWALARL TEKTQRRRLG PVPPGLCGRH WEPLRLFCED DQRPVCLVCR ESQEHQTHAM 
       130        140        150        160        170        180 
APIDEAFESY RTGNFDIHVD EWKRRLIRLL LYHFKQEEKL LKSQRNLVAK MKKVMHLQDV 
       190        200        210        220        230        240 
EVKNATQWKD KIKSQRMRIS TEFSKLHNFL VEEEDLFLQR LNKEEEETKK KLNENTLKLN 
       250        260        270        280        290        300 
QTIASLKKLI LEVGEKSQAP TLELLQNPKE VLTRSEIQDV NYSLEAVKVK TVCQIPLMKE 
       310        320        330        340        350        360 
MLKRFQVAVN LAEDTAHPKL VFSQEGRYVK NTASASSWPV FSSAWNYFAG WRNPQKTAFV 
       370        380        390        400        410        420 
ERFQHLPCVL GKNVFTSGKH YWEVESRDSL EVAVGVCRED VMGITDRSKM SPDVGIWAIY 
       430        440        450        460        470        480 
WSAAGYWPLI GFPGTPTQQE PALHRVGVYL DRGTGNVSFY SAVDGVHLHT FSCSSVSRLR 
       490        500    
PFFWLSPLAS LVIPPVTDRK 



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9C037-1-unknown MEAEDI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9C037-1-unknown MEAEDI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93063
    Q9C037-1-unknown MEAEDI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93064

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VTDRK 500 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VTDRK 500 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88681

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)