Q9C0D5: Protein TANC1

General Information

Protein names	- Protein TANC1 - Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1
Gene names	TANC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9C0D5

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLKAVLKKSR EGGKGGKKEA GSDFGPETSP VLHLDHSADS PVSSLPTAED TYRVSLAKGV
        70         80         90        100        110        120
SMSLPSSPLL PRQSHLVQSR VNKKSPGPVR KPKYVESPRV PGDAVIMPFR EVAKPTEPDE
       130        140        150        160        170        180
HEAKADNEPS CSPAAQELLT RLGFLLGEGI PSATHITIED KNETMCTALS QGISPCSTLT
       190        200        210        220        230        240
SSTASPSTDS PCSTLNSCVS KTAANKSPCE TISSPSSTLE SKDSGIIATI TSSSENDDRS
       250        260        270        280        290        300
GSSLEWNKDG NLRLGVQKGV LHDRRADNCS PVAEEETTGS AESTLPKAES SAGDGPVPYS
       310        320        330        340        350        360
QGSSSLIMPR PNSVAATSST KLEDLSYLDG QRNAPLRTSI RLPWHNTAGG RAQEVKARFA
       370        380        390        400        410        420
PYKPQDILLK PLLFEVPSIT TDSVFVGRDW LFHQIEENLR NTELAENRGA VVVGNVGFGK
       430        440        450        460        470        480
TAIISKLVAL SCHGSRMRQI ASNSPGSSPK TSDPTQDLHF TPLLSPSSST SASSTAKTPL
       490        500        510        520        530        540
GSISAENQRP REDAVKYLAS KVVAYHYCQA DNTYTCLVPE FVHSIAALLC RSHQLAAYRD
       550        560        570        580        590        600
LLIKEPQLQS MLSLRSCVQD PVAAFKRGVL EPLTNLRNEQ KIPEEEYIIL IDGLNEAEFH
       610        620        630        640        650        660
KPDYGDTLSS FITKIISKFP AWLKLIVTVR ANFQEIISAL PFVKLSLDDF PDNKDIHSDL
       670        680        690        700        710        720
HAYVQHRVHS SQDILSNISL NGKADATLIG KVSSHLVLRS LGSYLYLKLT LDLFQRGHLV
       730        740        750        760        770        780
IKSASYKVVP VSLSELYLLQ CNMKFMTQSA FERALPILNV ALASLHPMTD EQIFQAINAG
       790        800        810        820        830        840
HIQGEQGWED FQQRMDALSC FLIKRRDKTR MFCHPSFREW LVWRADGENT AFLCEPRNGH
       850        860        870        880        890        900
ALLAFMFSRQ EGKLNRQQTM ELGHHILKAH IFKGLSKKTG ISSSHLQALW IGYSTEGLSA
       910        920        930        940        950        960
ALASLRNLYT PNVKVSRLLI LGGANVNYRT EVLNNAPILC VQSHLGHEEV VTLLLEFGAC
       970        980        990       1000       1010       1020
LDGTSENGMT ALCYAAAAGH MKLVCLLTKK GVRVDHLDKK GQCALVHSAL RGHGDILQYL
      1030       1040       1050       1060       1070       1080
LTCEWSPGPP QPGTLRKSHA LQQALTAAAS MGHSSVVQCL LGMEKEHEVE VNGTDTLWGE
      1090       1100       1110       1120       1130       1140
TALTAAAGRG KLEVCELLLG HGAAVSRTNR RGVPPLFCAA RQGHWQIVRL LLERGCDVNL
      1150       1160       1170       1180       1190       1200
SDKQGRTPLM VAACEGHLST VEFLLSKGAA LSSLDKEGLS ALSWACLKGH RAVVQYLVEE
      1210       1220       1230       1240       1250       1260
GAAIDQTDKN GRTPLDLAAF YGDAETVLYL VEKGAVIEHV DHSGMRPLDR AIGCRNTSVV
      1270       1280       1290       1300       1310       1320
VALLRKGAKL GNAAWAMATS KPDILIILLQ KLMEEGNVMY KKGKMKEAAQ RYQYALRKFP
      1330       1340       1350       1360       1370       1380
REGFGEDMRP FNELRVSLYL NLSRCRRKTN DFGMAEEFAS KALELKPKSY EAFYARARAK
      1390       1400       1410       1420       1430       1440
RNSRQFVAAL ADLQEAVKLC PTNQEVKRLL ARVEEECKQL QRSQQQKQQG PLPAPLNDSE
      1450       1460       1470       1480       1490       1500
NEEDTPTPGL SDHFHSEETE EEETSPQEES VSPTPRSQPS SSVPSSYIRN LQEGLQSKGR
      1510       1520       1530       1540       1550       1560
PVSPQSRAGI GKSLREPVAQ PGLLLQPSKQ AQIVKTSQHL GSGQSAVRNG SMKVQISSQN
      1570       1580       1590       1600       1610       1620
PPPSPMPGRI AATPAGSRTQ HLEGTGTFTT RAGCGHFGDR LGPSQNVRLQ CGENGPAHPL
      1630       1640       1650       1660       1670       1680
PSKTKTTERL LSHSSVAVDA APPNQGGLAT CSDVRHPASL TSSGSSGSPS SSIKMSSSTS
      1690       1700       1710       1720       1730       1740
SLTSSSSFSD GFKVQGPDTR IKDKVVTHVQ SGTAEHRPRN TPFMGIMDKT ARFQQQSNPP
      1750       1760       1770       1780       1790       1800
SRSWHCPAPE GLLTNTSSAA GLQSANTEKP SLMQVGGYNN QAKTCSVSTL SASVHNGAQV
      1810       1820       1830       1840       1850       1860
KELEESKCQI PVHSQENRIT KTVSHLYQES ISKQQPHISN EAHRSHLTAA KPKRSFIESN

V

Isoforms

- Isoform 2 of Protein TANC1

Sequence View

        10         20         30         40         50         60
MLKAVLKKSR EGGKGGKKEA GSDFGPETSP VLHLDHSADS PVSSLPTAED TYRVSLAKGV
        70         80         90        100        110        120
SMSLPSSPLL PRQSHLVQSR VNKKSPGPVR KPKYVESPRV PGDAVIMPFR EVAKPTEPDE
       130        140        150        160        170        180
HEAKADNEPS CSPAAQELLT RLGFLLGEGI PSATHITIED KNETMCTALS QGISPCSTLT
       190        200        210        220        230        240
SSTASPSTDS PCSTLNSCVS KTAANKSPCE TISSPSSTLE SKDSGIIATI TSSSENDDRS
       250        260        270        280        290        300
GSSLEWNKDG NLRLGVQKGV LHDRRADNCS PVAEEETTGS AESTLPKAES SAGDGPVPYS
       310        320        330        340        350        360
QGSSSLIMPR PNSVAATSST KLEDLSYLDG QRNAPLRTSI RLPWHNTAGG RAQEVKARFA
       370        380        390        400        410        420
PYKPQDILLK PLLFEVPSIT TDSVFVGRDW LFHQIEENLR NTELAENRGA VVVGNVGFGK
       430        440        450        460        470        480
TAIISKLVAL SCHGSRMRQI ASNSPGSSPK TSDPTQDLHF TPLLSPSSST SASSTAKTPL
       490        500        510        520        530        540
GSISAENQRP REDAVKYLAS KVVAYHYCQA DNTYTCLVPE FVHSIAALLC RSHQLAAYRD
       550        560        570        580        590        600
LLIKEPQLQS MLSLRSCVQD PVAAFKRGVL EPLTNLRNEQ KIPEEEYIIL IDGLNEAEFH
       610        620        630        640        650        660
KPDYGDTLSS FITKIISKFP AWLKLIVTVR ANFQEIISAL PFVKLSLDDF PDNKDIHSDL
       670        680        690        700        710        720
HAYVQHRVHS SQDILSNISL NGKADATLIG KVSSHLVLRS LGSYLYLKLT LDLFQRGHLV
       730        740        750        760        770        780
IKSASYKVVP VSLSELYLLQ CNMKFMTQSA FERALPILNV ALASLHPMTD EQIFQAINAG
       790        800        810        820        830        840
HIQGEQGWED FQQRMDALSC FLIKRRDKTR MFCHPSFREW LVWRADGENT AFLCEPRNGH
       850        860        870        880        890        900
ALLAFMFSRQ EGKLNRQQTM ELGHHILKAH IFKGLSKKTG ISSSHLQALW IGYSTEGLSA
       910        920        930        940        950        960
ALASLRNLYT PNVKVSRLLI LGGANVNYRT EVLNNAPILC VQSHLGHEEV VTLLLEFGAC
       970        980        990       1000       1010       1020
LDGTSENGMT ALCYAAAAGH MKLVCLLTKK GVRVDHLDKK GQCALVHSAL RGHGDILQYL
      1030       1040       1050       1060       1070       1080
LTCEWSPGPP QPGTLRKSHA LQQALTAAAS MGHSSVVQCL LGMEKEHEVE VNGTDTLWGE
      1090       1100       1110       1120       1130       1140
TALTAAAGRG KLEVCELLLG HGAAVSRTNR RGVPPLFCAA RQGHWQIVRL LLERGCDVNL
      1150       1160       1170       1180       1190       1200
SDKQGRTPLM VAACEGHLST VEFLLSKGAA LSSLDKEGLS ALSWACLKGH RAVVQYLVEE
      1210       1220       1230       1240       1250       1260
GAAIDQTDKN GRTPLDLAAF YGDAETVLYL VEKGAVIEHV DHSGMRPLDR AIGCRNTSVV
      1270       1280       1290       1300       1310       1320
VALLRKGAKL GNAAWAMATS KPDILIILLQ KLMEEGNVMY KKGKMKEAAQ RYQYALRKFP
      1330       1340       1350       1360       1370       1380
REGFGEDMRP FNELRVSLYL NLSRCRRKTN DFGMAEEFAS KALELKPKSY EAFYARARAK
      1390       1400       1410       1420       1430       1440
RNSRQFVAAL ADLQEAVKLC PTNQEVKRLL ARVEEECKQL QRSQQQKQQG PLPAPLNDSE
      1450       1460       1470       1480       1490       1500
NEEDTPTPGL SDHFHSEETE EEETSPQEES VSPTPRSQPS SSVPSSYIRN LQEGLQSKGR
      1510       1520       1530       1540       1550       1560
PVSPQSRAGI GKSLREPVAQ PGLLLQPSKQ AQIVKTSQHL GSGQSAVRNG SMKVQISSQN
      1570       1580       1590       1600       1610       1620
PPPSPMPGRI AATPAGSRTQ HLEGTGTFTT RAGCGHFGDR LGPSQNVRLQ CGENGPAHPL
      1630       1640       1650       1660       1670       1680
PSKTKTTERL LSHSSVAVDA APPNQGGLAT CSDVRHPASL TSSGSSGSPS SSIKMSSSTS
      1690       1700       1710       1720       1730       1740
SLTSSSSFSD GFKVQGPDTR IKDKVVTHVQ SGTAEHRPRN TPFMGIMDKT ARFQQQSNPP
      1750       1760       1770       1780       1790       1800
SRSWHCPAPE GLLTNTSSAA GLQSANTEKP SLMQVGGYNN QAKTCSVSTL SASVHNGAQV
      1810       1820       1830       1840       1850       1860
KELEESKCQI PVHSQENRIT KTVSHLYQES ISKQQPHISN EAHRSHLTAA KPKRSFIESN

V

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9C0D5-1-unknown	MLKAVL...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91499
Q9C0D5-1-Acetylation	MLKAVL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9C0D5-1-Acetylation	MLKAVL...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9C0D5-1-Acetylation	MLKAVL...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106963
Q9C0D5-1764-unknown	SANTEK...	1764		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt167828
Q9C0D5-1764-	SANTEK...	1764			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9C0D5-1764-	SANTEK...	1764			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IESNV	1861	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...IESNV	1861	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt87117

TopFIND

Q9C0D5: Protein TANC1

General Information

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Methodology:

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates