TopFIND 4.0

Q9C0I9: Leucine-rich repeat-containing protein 27

General Information

Protein names
- Leucine-rich repeat-containing protein 27
Gene names LRRC27
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9C0I9

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL 
        70         80         90        100        110        120 
EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL 
       130        140        150        160        170        180 
LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN 
       190        200        210        220        230        240 
PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL 
       250        260        270        280        290        300 
SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE 
       310        320        330        340        350        360 
LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK 
       370        380        390        400        410        420 
RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE 
       430        440        450        460        470        480 
KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV 
       490        500        510        520        530    
LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ 

Isoforms

- Isoform 2 of Leucine-rich repeat-containing protein 27 - Isoform 3 of Leucine-rich repeat-containing protein 27 - Isoform 4 of Leucine-rich repeat-containing protein 27

Sequence View

        10         20         30         40         50         60 
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL 
        70         80         90        100        110        120 
EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL 
       130        140        150        160        170        180 
LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN 
       190        200        210        220        230        240 
PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL 
       250        260        270        280        290        300 
SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE 
       310        320        330        340        350        360 
LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK 
       370        380        390        400        410        420 
RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE 
       430        440        450        460        470        480 
KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV 
       490        500        510        520        530    
LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ          10         20         30         40         50         60 
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL 
        70         80         90        100        110        120 
EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL 
       130        140        150        160        170        180 
LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN 
       190        200        210        220        230        240 
PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL 
       250        260        270        280        290        300 
SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE 
       310        320        330        340        350        360 
LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK 
       370        380        390        400        410        420 
RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE 
       430        440        450        460        470        480 
KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV 
       490        500        510        520        530    
LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ          10         20         30         40         50         60 
MEGSSSYEVP SVAAADLEEG AGQTRSLPAT PSKDVHKGVG GIIFSSSPIL DLSESGLCRL 
        70         80         90        100        110        120 
EEVFRIPSLQ QLHLQRNALC VIPQDFFQLL PNLTWLDLRY NRIKALPSGI GAHQHLKTLL 
       130        140        150        160        170        180 
LERNPIKMLP VELGSVTTLK ALNLRHCPLE FPPQLVVQKG LVAIQRFLRM WAVEHSLPRN 
       190        200        210        220        230        240 
PTSQEAPPVR EMTLRDLPSP GLELSGDHAS NQGAVNAQDP EGAVMKEKAS FLPPVEKPDL 
       250        260        270        280        290        300 
SELRKSADSS ENWPSEEEIR RFWKLRQEIV EHVKADVLGD QLLTRELPPN LKAALNIEKE 
       310        320        330        340        350        360 
LPKPRHVFRR KTASSRSILP DLLSPYQMAI RAKRLEESRA AALRELQEKQ ALMEQQRREK 
       370        380        390        400        410        420 
RALQEWRERA QRMRKRKEEL SKLLPPRRSM VASKIPSATD LIDNRKVPLN PPGKMKPSKE 
       430        440        450        460        470        480 
KSPQASKEMS ALQERNLEEK IKQHVLQMRE QRRFHGQAPL EEMRKAAEDL EIATELQDEV 
       490        500        510        520        530    
LKLKLGLTLN KDRRRAALTG NLSLGLPAAQ PQNTFFNTKY GESGNVRRYQ 



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9C0I9-1-unknown MEGSSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9C0I9-1-unknown MEGSSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79892
    Q9C0I9-1-unknown MEGSSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79893

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VRRYQ 530 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VRRYQ 530 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75509

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)