TopFIND 4.0

Q9CQG2: RNA N6-adenosine-methyltransferase METTL16 {ECO:0000305}

General Information

Protein names
- RNA N6-adenosine-methyltransferase METTL16 {ECO:0000305}
- Methyltransferase 10 domain-containing protein
- Methyltransferase-like protein 16
- N6-adenosine-methyltransferase METTL16 {ECO:0000250|UniProtKB:Q86W50}
- 2.1.1.348 {ECO:0000305|PubMed:29262316}
- U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase {ECO:0000250|UniProtKB:Q86W50}
- 2.1.1.346 {ECO:0000250|UniProtKB:Q86W50}
Gene names Mettl16
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9CQG2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALSKSMHAR NRYKDKPPDF AYLASKYPDF KQHIQINLNG RVSLNFKDPE AVRALTCTLL 
        70         80         90        100        110        120 
REDFGLSIDI PLERLIPTVP LRLNYIHWVE DLIGHQDSDK TTLRRGIDIG TGASCIYPLL 
       130        140        150        160        170        180 
GATLNGWYFL ATEVDDMCFN YAKKNVEQNN LSDLIKVVKV PQKTLLMDAL KEESEIVYDF 
       190        200        210        220        230        240 
CMCNPPFFAN QLEAKGVNSR NSRRPPPSSV NTGGITEIMA EGGELEFVKR IIHDSLQLKK 
       250        260        270        280        290        300 
RLRWYSCMLG KKCSLAPLKE ELRIQGVPKV TFTEFCQGRT MRWALAWSFY DDVTVPSPPS 
       310        320        330        340        350        360 
KRRKLEKPRK PITFVVLESV MKELSLKASS LGSETAEGIV VVTTWIEKIL TDLKVQHKRI 
       370        380        390        400        410        420 
PCGREEVSLF LTAIENSWIH LRRKRRERVR QLREVPRAPE DVILALEERK STPKELSSGQ 
       430        440        450        460        470        480 
DVAHSPQESA LCGLDVPGGE AAADGGHCLS QKLLCQEETP EATEDERDEE RGGMEAMESC 
       490        500        510        520        530        540 
KGSSNGAQDG EASEKGDRLD GAAGRYLFKC LVNIKKEAGD AVVEMHWVEG QNRDLMNQLC 
       550    
TYVRNQILRL VAS

Isoforms

- Isoform 2 of Methyltransferase-like protein 16 - Isoform 2 of RNA N6-adenosine-methyltransferase METTL16

Sequence View

        10         20         30         40         50         60 
MALSKSMHAR NRYKDKPPDF AYLASKYPDF KQHIQINLNG RVSLNFKDPE AVRALTCTLL 
        70         80         90        100        110        120 
REDFGLSIDI PLERLIPTVP LRLNYIHWVE DLIGHQDSDK TTLRRGIDIG TGASCIYPLL 
       130        140        150        160        170        180 
GATLNGWYFL ATEVDDMCFN YAKKNVEQNN LSDLIKVVKV PQKTLLMDAL KEESEIVYDF 
       190        200        210        220        230        240 
CMCNPPFFAN QLEAKGVNSR NSRRPPPSSV NTGGITEIMA EGGELEFVKR IIHDSLQLKK 
       250        260        270        280        290        300 
RLRWYSCMLG KKCSLAPLKE ELRIQGVPKV TFTEFCQGRT MRWALAWSFY DDVTVPSPPS 
       310        320        330        340        350        360 
KRRKLEKPRK PITFVVLESV MKELSLKASS LGSETAEGIV VVTTWIEKIL TDLKVQHKRI 
       370        380        390        400        410        420 
PCGREEVSLF LTAIENSWIH LRRKRRERVR QLREVPRAPE DVILALEERK STPKELSSGQ 
       430        440        450        460        470        480 
DVAHSPQESA LCGLDVPGGE AAADGGHCLS QKLLCQEETP EATEDERDEE RGGMEAMESC 
       490        500        510        520        530        540 
KGSSNGAQDG EASEKGDRLD GAAGRYLFKC LVNIKKEAGD AVVEMHWVEG QNRDLMNQLC 
       550    
TYVRNQILRL VAS         10         20         30         40         50         60 
MALSKSMHAR NRYKDKPPDF AYLASKYPDF KQHIQINLNG RVSLNFKDPE AVRALTCTLL 
        70         80         90        100        110        120 
REDFGLSIDI PLERLIPTVP LRLNYIHWVE DLIGHQDSDK TTLRRGIDIG TGASCIYPLL 
       130        140        150        160        170        180 
GATLNGWYFL ATEVDDMCFN YAKKNVEQNN LSDLIKVVKV PQKTLLMDAL KEESEIVYDF 
       190        200        210        220        230        240 
CMCNPPFFAN QLEAKGVNSR NSRRPPPSSV NTGGITEIMA EGGELEFVKR IIHDSLQLKK 
       250        260        270        280        290        300 
RLRWYSCMLG KKCSLAPLKE ELRIQGVPKV TFTEFCQGRT MRWALAWSFY DDVTVPSPPS 
       310        320        330        340        350        360 
KRRKLEKPRK PITFVVLESV MKELSLKASS LGSETAEGIV VVTTWIEKIL TDLKVQHKRI 
       370        380        390        400        410        420 
PCGREEVSLF LTAIENSWIH LRRKRRERVR QLREVPRAPE DVILALEERK STPKELSSGQ 
       430        440        450        460        470        480 
DVAHSPQESA LCGLDVPGGE AAADGGHCLS QKLLCQEETP EATEDERDEE RGGMEAMESC 
       490        500        510        520        530        540 
KGSSNGAQDG EASEKGDRLD GAAGRYLFKC LVNIKKEAGD AVVEMHWVEG QNRDLMNQLC 
       550    
TYVRNQILRL VAS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9CQG2-1-unknown MALSKS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9CQG2-1-unknown MALSKS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80927
    Q9CQG2-18-unknown PDFAYL... 18 inferred from electronic annotation unknown TISdb inferred from TISdb
    Q9CQG2-18-unknown PDFAYL... 18 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195112

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLVAS 553 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RLVAS 553 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76545

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)