TopFIND 4.0

Q9CY62: E3 ubiquitin-protein ligase RNF181

General Information

Protein names
- E3 ubiquitin-protein ligase RNF181
- 2.3.2.27
- RING finger protein 181
- RING-type E3 ubiquitin transferase RNF181 {ECO:0000305}
Gene names Rnf181
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9CY62

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASYFDEHDC EPLNPEREAR NNMLLELARR VRGAWSWAPG GRSLFNRMDF EDLGLVDWEH 
        70         80         90        100        110        120 
HLPPPAAKAV VESLPRTVIS SAKADLKCPV CLLEFEAEET VIEMPCHHLF HSNCILPWLS 
       130        140        150        160    
KTNSCPLCRH ELPTDDDSYE EHKKDKARRQ QQQHRLENLH GAMYT

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF181 - Isoform 3 of E3 ubiquitin-protein ligase RNF181

Sequence View

        10         20         30         40         50         60 
MASYFDEHDC EPLNPEREAR NNMLLELARR VRGAWSWAPG GRSLFNRMDF EDLGLVDWEH 
        70         80         90        100        110        120 
HLPPPAAKAV VESLPRTVIS SAKADLKCPV CLLEFEAEET VIEMPCHHLF HSNCILPWLS 
       130        140        150        160    
KTNSCPLCRH ELPTDDDSYE EHKKDKARRQ QQQHRLENLH GAMYT         10         20         30         40         50         60 
MASYFDEHDC EPLNPEREAR NNMLLELARR VRGAWSWAPG GRSLFNRMDF EDLGLVDWEH 
        70         80         90        100        110        120 
HLPPPAAKAV VESLPRTVIS SAKADLKCPV CLLEFEAEET VIEMPCHHLF HSNCILPWLS 
       130        140        150        160    
KTNSCPLCRH ELPTDDDSYE EHKKDKARRQ QQQHRLENLH GAMYT



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9CY62-1-unknown MASYFD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9CY62-48-unknown MDFEDL... 48 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87930

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)