TopFIND 4.0

Q9CYU6: Diphthine methyltransferase

General Information

Protein names
- Diphthine methyltransferase
- 3.1.1.97
- Diphthamide biosynthesis protein 7
- DPH7
- WD repeat-containing protein 85
Gene names Dph7
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9CYU6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGSHAGTLR VLQAVDTELT ADSVEWCPVE GYQHLLACGT YQLRAPRDQP ALDGSEPQVR 
        70         80         90        100        110        120 
LGRLYLFSFS EHNTAKPLLE VQRRDSSAVL DMKWCHIPVS GHVLLGLANA SGSIGLLRLM 
       130        140        150        160        170        180 
ECENNSYTLQ PISSLALDEN CLSLSMDWST GKSVRAREQP LKIISSDSKG QLHLLMVNEG 
       190        200        210        220        230        240 
TAELQLVASW PAHHFEAWIA AFNYWQTELV YSGGDDCLLR GWDTRMLGTP VFTSKRHCMG 
       250        260        270        280        290        300 
VCSIQSSPHQ EHILATGSYD EHVLLWDTRN IRQPLADVPV QGGVWRLKWH PVHHHLLLAA 
       310        320        330        340        350        360 
CMHNGFKILN CQKAIEEKQD ITVLTSHEMP NSLVYGADWS WLFHSMKPTP TWFFDQNDMG 
       370        380        390        400        410        420 
VKAADHSSLK VTEEPPIHSQ EQTMDRQVEG PANAHTRAEL KASLLPLTED MKNSKDCSSS 
       430        440        450        460        470    
SVKTRDLSHC SGGQSFDNSL LATCSFYDHV LHLWKWETNQ ARTLCSGTGC DLGSADH

Isoforms

- Isoform 2 of Diphthamide biosynthesis protein 7 - Isoform 2 of Diphthine methyltransferase

Sequence View

        10         20         30         40         50         60 
MAGSHAGTLR VLQAVDTELT ADSVEWCPVE GYQHLLACGT YQLRAPRDQP ALDGSEPQVR 
        70         80         90        100        110        120 
LGRLYLFSFS EHNTAKPLLE VQRRDSSAVL DMKWCHIPVS GHVLLGLANA SGSIGLLRLM 
       130        140        150        160        170        180 
ECENNSYTLQ PISSLALDEN CLSLSMDWST GKSVRAREQP LKIISSDSKG QLHLLMVNEG 
       190        200        210        220        230        240 
TAELQLVASW PAHHFEAWIA AFNYWQTELV YSGGDDCLLR GWDTRMLGTP VFTSKRHCMG 
       250        260        270        280        290        300 
VCSIQSSPHQ EHILATGSYD EHVLLWDTRN IRQPLADVPV QGGVWRLKWH PVHHHLLLAA 
       310        320        330        340        350        360 
CMHNGFKILN CQKAIEEKQD ITVLTSHEMP NSLVYGADWS WLFHSMKPTP TWFFDQNDMG 
       370        380        390        400        410        420 
VKAADHSSLK VTEEPPIHSQ EQTMDRQVEG PANAHTRAEL KASLLPLTED MKNSKDCSSS 
       430        440        450        460        470    
SVKTRDLSHC SGGQSFDNSL LATCSFYDHV LHLWKWETNQ ARTLCSGTGC DLGSADH         10         20         30         40         50         60 
MAGSHAGTLR VLQAVDTELT ADSVEWCPVE GYQHLLACGT YQLRAPRDQP ALDGSEPQVR 
        70         80         90        100        110        120 
LGRLYLFSFS EHNTAKPLLE VQRRDSSAVL DMKWCHIPVS GHVLLGLANA SGSIGLLRLM 
       130        140        150        160        170        180 
ECENNSYTLQ PISSLALDEN CLSLSMDWST GKSVRAREQP LKIISSDSKG QLHLLMVNEG 
       190        200        210        220        230        240 
TAELQLVASW PAHHFEAWIA AFNYWQTELV YSGGDDCLLR GWDTRMLGTP VFTSKRHCMG 
       250        260        270        280        290        300 
VCSIQSSPHQ EHILATGSYD EHVLLWDTRN IRQPLADVPV QGGVWRLKWH PVHHHLLLAA 
       310        320        330        340        350        360 
CMHNGFKILN CQKAIEEKQD ITVLTSHEMP NSLVYGADWS WLFHSMKPTP TWFFDQNDMG 
       370        380        390        400        410        420 
VKAADHSSLK VTEEPPIHSQ EQTMDRQVEG PANAHTRAEL KASLLPLTED MKNSKDCSSS 
       430        440        450        460        470    
SVKTRDLSHC SGGQSFDNSL LATCSFYDHV LHLWKWETNQ ARTLCSGTGC DLGSADH



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9CYU6-1-unknown MAGSHA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GSADH 477 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GSADH 477 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68809

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)