Q9D0L8: mRNA cap guanine-N7 methyltransferase

General Information

Protein names	- mRNA cap guanine-N7 methyltransferase - 2.1.1.56 {ECO:0000250\|UniProtKB:O43148} - RG7MT1 - mRNA (guanine-N(7)-)-methyltransferase - mRNA cap methyltransferase
Gene names	Rnmt
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9D0L8

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of mRNA cap guanine-N7 methyltransferase - Isoform 3 of mRNA cap guanine-N7 methyltransferase

Sequence View

        10         20         30         40         50         60
MEGSAKASVA SDPESPPGGN EPAAASGQRL PENTPPCQQV DQPKMQKEFG EDLVEQNSSY
        70         80         90        100        110        120
VQDSPSKKRK LDVEIILEEK HSEDDGGSAK RSKLERGDVS EDEPSLGRLN QTKRKLQPQD
       130        140        150        160        170        180
DEVPQKLQKL EEGHSSAVAA HYNELQEVGL AKRSQSRIFY LRNFNNWIKS ILIGEILEKV
       190        200        210        220        230        240
RQRKTRDITV LDLGCGKGGD LLKWRKGRIS RLVCADIADI SMKQCQQRYE DMRCRRDNEH
       250        260        270        280        290        300
IFSAEFITAD CSKELLVEKF RDPEMYFDVC SCQFACHYSF ESQVQADTML RNACGRLNPG
       310        320        330        340        350        360
GYFIGTTPNS FELIRRLEAS ETESFGNEIY TVKFQKKGNY PLFGCKYDFN LEGVVDVPEF
       370        380        390        400        410        420
LVYFPLLTEM AKKYNMKLIY KKTFLEFYEE KIKNNENKML LKRMQALEQY PAHENSKLAS
       430        440        450        460
EKVGDYTHAA EYLKKSQVRL PLGTLSKSEW EATSIYLVFA FEKQQ         10         20         30         40         50         60
MEGSAKASVA SDPESPPGGN EPAAASGQRL PENTPPCQQV DQPKMQKEFG EDLVEQNSSY
        70         80         90        100        110        120
VQDSPSKKRK LDVEIILEEK HSEDDGGSAK RSKLERGDVS EDEPSLGRLN QTKRKLQPQD
       130        140        150        160        170        180
DEVPQKLQKL EEGHSSAVAA HYNELQEVGL AKRSQSRIFY LRNFNNWIKS ILIGEILEKV
       190        200        210        220        230        240
RQRKTRDITV LDLGCGKGGD LLKWRKGRIS RLVCADIADI SMKQCQQRYE DMRCRRDNEH
       250        260        270        280        290        300
IFSAEFITAD CSKELLVEKF RDPEMYFDVC SCQFACHYSF ESQVQADTML RNACGRLNPG
       310        320        330        340        350        360
GYFIGTTPNS FELIRRLEAS ETESFGNEIY TVKFQKKGNY PLFGCKYDFN LEGVVDVPEF
       370        380        390        400        410        420
LVYFPLLTEM AKKYNMKLIY KKTFLEFYEE KIKNNENKML LKRMQALEQY PAHENSKLAS
       430        440        450        460
EKVGDYTHAA EYLKKSQVRL PLGTLSKSEW EATSIYLVFA FEKQQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9D0L8-1-unknown	MEGSAK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9D0L8-1-unknown	MEGSAK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80604
Q9D0L8-1-unknown	MEGSAK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80605
Q9D0L8-54-unknown	VEQNSS...	54	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31064
Q9D0L8-54-unknown	VEQNSS...	54	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139456
Q9D0L8-54-unknown	VEQNSS...	54	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139458

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FGEDLV	53	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31064
...FGEDLV	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122543
...FGEDLV	53	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122545
...PLLTEM	369	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76222
...FEKQQ	465	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FEKQQ	465	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76223

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	53	EDLV.\|.VEQN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MCES_MOUSE @53

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)