Q9D110: 5-formyltetrahydrofolate cyclo-ligase

General Information

Protein names	- 5-formyltetrahydrofolate cyclo-ligase - 6.3.3.2 - 5,10-methenyl-tetrahydrofolate synthetase - MTHFS - Methenyl-THF synthetase
Gene names	Mthfs
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9D110

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVTVNSAK RGLRAELKQR LRALSAEERL RQSLLLTQKV IAHNQYQNSK RISIFLSMQD
        70         80         90        100        110        120
EVETEVIIKD IFKQGKICFI PRYQFQSNHM DMVRLTSSEE IALLPKTSWN IHQPGEGDVR
       130        140        150        160        170        180
EEALSTGGLD LIFLPGLGFD KDGNRLGRGK GYYDTYLKRC VQHQEVKPYT MALAFKEQIC
       190        200
PQIPVDEHDM KVDEVLYEDS PAS

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9D110-2-unknown	MAAVTV...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9D110-2-unknown	MAAVTV...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9D110-2-Acetylation	AAVTVN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9D110-2-Acetylation	AAVTVN...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9D110-58-unknown	MQDEVE...	58		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000112854
Q9D110-58-unknown	MQDEVE...	58		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000112390
Q9D110-58-unknown	MQDEVE...	58		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118531
Q9D110-132-unknown	IFLPGL...	132		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31070

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EALSTG	126	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119881
...GGLDLI	131	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31070
...EVKPYT	169	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118531
...DSPAS	203	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	131	LDLI.\|.IFLP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MTHFS_MOUSE @131

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)