TopFIND 4.0

Q9D2Y4: Mixed lineage kinase domain-like protein

General Information

Protein names
- Mixed lineage kinase domain-like protein
Gene names Mlkl
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9D2Y4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDKLGQIIKL GQLIYEQCEK MKYCRKQCQR LGNRVHGLLQ PLQRLQAQGK KNLPDDITAA 
        70         80         90        100        110        120 
LGRFDEVLKE ANQQIEKFSK KSHIWKFVSV GNDKILFHEV NEKLRDVWEE LLLLLQVYHW 
       130        140        150        160        170        180 
NTVSDVSQPA SWQQEDRQDA EEDGNENMKV ILMQLQISVE EINKTLKQCS LKPTQEIPQD 
       190        200        210        220        230        240 
LQIKEIPKEH LGPPWTKLKT SKMSTIYRGE YHRSPVTIKV FNNPQAESVG IVRFTFNDEI 
       250        260        270        280        290        300 
KTMKKFDSPN ILRIFGICID QTVKPPEFSI VMEYCELGTL RELLDREKDL TMSVRSLLVL 
       310        320        330        340        350        360 
RAARGLYRLH HSETLHRNIS SSSFLVAGGY QVKLAGFELS KTQNSISRTA KSTKAERSSS 
       370        380        390        400        410        420 
TIYVSPERLK NPFCLYDIKA EIYSFGIVLW EIATGKIPFE GCDSKKIREL VAEDKKQEPV 
       430        440        450        460        470    
GQDCPELLRE IINECRAHEP SQRPSVDGRS LSGRERILER LSAVEESTDK KV

Isoforms

- Isoform 2 of Mixed lineage kinase domain-like protein

Sequence View

        10         20         30         40         50         60 
MDKLGQIIKL GQLIYEQCEK MKYCRKQCQR LGNRVHGLLQ PLQRLQAQGK KNLPDDITAA 
        70         80         90        100        110        120 
LGRFDEVLKE ANQQIEKFSK KSHIWKFVSV GNDKILFHEV NEKLRDVWEE LLLLLQVYHW 
       130        140        150        160        170        180 
NTVSDVSQPA SWQQEDRQDA EEDGNENMKV ILMQLQISVE EINKTLKQCS LKPTQEIPQD 
       190        200        210        220        230        240 
LQIKEIPKEH LGPPWTKLKT SKMSTIYRGE YHRSPVTIKV FNNPQAESVG IVRFTFNDEI 
       250        260        270        280        290        300 
KTMKKFDSPN ILRIFGICID QTVKPPEFSI VMEYCELGTL RELLDREKDL TMSVRSLLVL 
       310        320        330        340        350        360 
RAARGLYRLH HSETLHRNIS SSSFLVAGGY QVKLAGFELS KTQNSISRTA KSTKAERSSS 
       370        380        390        400        410        420 
TIYVSPERLK NPFCLYDIKA EIYSFGIVLW EIATGKIPFE GCDSKKIREL VAEDKKQEPV 
       430        440        450        460        470    
GQDCPELLRE IINECRAHEP SQRPSVDGRS LSGRERILER LSAVEESTDK KV



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9D2Y4-1-unknown MDKLGQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9D2Y4-1-unknown MDKLGQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81255

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TDKKV 472 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)