TopFIND 4.0

Q9DBY1: E3 ubiquitin-protein ligase synoviolin

General Information

Protein names
- E3 ubiquitin-protein ligase synoviolin
- 2.3.2.27
- RING-type E3 ubiquitin transferase synoviolin {ECO:0000305}
- Synovial apoptosis inhibitor 1
Gene names Syvn1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9DBY1

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKV 
        70         80         90        100        110        120 
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 
       130        140        150        160        170        180 
EDRVDFMERS PNISWLFHCR IVSLMFLLGI LDFLFVSHAY HSILTRGASV QLVFGFEYAI 
       190        200        210        220        230        240 
LMTMVLTIFI KYVLHSVDLQ SENPWDNKAV YMLYTELFTG FIKVLLYMAF MTIMIKVHTF 
       250        260        270        280        290        300 
PLFAIRPMYL AMRQFKKAVT DAIMSRRAIR NMNTLYPDAT PEELQAVDNV CIICREEMVT 
       310        320        330        340        350        360 
GAKRLPCNHI FHTSCLRSWF QRQQTCPTCR MDVLRASLPA QSPPPPEPAD QGPPPAPHPQ 
       370        380        390        400        410        420 
PLLPQPPNFP QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS GEAAAPPPTS TAVSRPSGAA 
       430        440        450        460        470        480 
TTTAAGTSTS APAPGSVPGP EAGPAPGFPF PPPWMGMPLP PPFAFPPMPV PPAGFAGLTP 
       490        500        510        520        530        540 
EELRALEGHE RQHLEARLQS LRNIHTLLDA AMLQINQYLT VLASLGPPRP ATSVNPTEET 
       550        560        570        580        590        600 
ASTVVSAAPS TSAPSSEAPT PSPGASPPIP EAEKPPAPES VGIVEELPED GEPDAAELRR 
       610    
RRLQKLESPV AH

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase synoviolin

Sequence View

        10         20         30         40         50         60 
MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKV 
        70         80         90        100        110        120 
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 
       130        140        150        160        170        180 
EDRVDFMERS PNISWLFHCR IVSLMFLLGI LDFLFVSHAY HSILTRGASV QLVFGFEYAI 
       190        200        210        220        230        240 
LMTMVLTIFI KYVLHSVDLQ SENPWDNKAV YMLYTELFTG FIKVLLYMAF MTIMIKVHTF 
       250        260        270        280        290        300 
PLFAIRPMYL AMRQFKKAVT DAIMSRRAIR NMNTLYPDAT PEELQAVDNV CIICREEMVT 
       310        320        330        340        350        360 
GAKRLPCNHI FHTSCLRSWF QRQQTCPTCR MDVLRASLPA QSPPPPEPAD QGPPPAPHPQ 
       370        380        390        400        410        420 
PLLPQPPNFP QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS GEAAAPPPTS TAVSRPSGAA 
       430        440        450        460        470        480 
TTTAAGTSTS APAPGSVPGP EAGPAPGFPF PPPWMGMPLP PPFAFPPMPV PPAGFAGLTP 
       490        500        510        520        530        540 
EELRALEGHE RQHLEARLQS LRNIHTLLDA AMLQINQYLT VLASLGPPRP ATSVNPTEET 
       550        560        570        580        590        600 
ASTVVSAAPS TSAPSSEAPT PSPGASPPIP EAEKPPAPES VGIVEELPED GEPDAAELRR 
       610    
RRLQKLESPV AH



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9DBY1-1-unknown MFRTAV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91326
    Q9DBY1-23-unknown YYLKHQ... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9DBY1-23-unknown YYLKHQ... 23 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113141
    Q9DBY1-149-unknown GILDFL... 149 inferred from electronic annotation unknown TISdb inferred from TISdb

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)