TopFIND 4.0

Q9EQH2: Endoplasmic reticulum aminopeptidase 1

General Information

Protein names
- Endoplasmic reticulum aminopeptidase 1
- 3.4.11.-
- ARTS-1
- Adipocyte-derived leucine aminopeptidase
- A-LAP
- Aminopeptidase PILS
- Puromycin-insensitive leucyl-specific aminopeptidase
- PILS-AP
- VEGF-induced aminopeptidase
Gene names Erap1
Organism Mus musculus
Protease Family
Protease ID M01.018
Chromosome location
UniProt ID Q9EQH2

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSLLPLVLT FLSVSSPSWC QNSDIESLKA SNGDSFPWNN MRLPEYMTPI HYDLMIHANL 
        70         80         90        100        110        120 
STLTFWGKTE VEIIASRPTS TIIMHSHHLQ ISKATLRRGA GEMLSEEPLK VLEYPAHEQV 
       130        140        150        160        170        180 
ALLAAQPLLA GSLYTVIIDY AANLSESFHG FYKSTYRTQE GEMRILAATQ FEPTAARMAF 
       190        200        210        220        230        240 
PCFDEPALKA SFSIKIKRDP RHLAISNMPL VKSVNVAEGL IEDHFDITVK MSTYLVAFII 
       250        260        270        280        290        300 
SDFKSVSKMT KSGVKVSVYA VPDKINQADY ALDAAVTLLE FYEDYFNIPY PLPKQDLAAI 
       310        320        330        340        350        360 
PDFQSGAMEN WGLTTYRESS LLYDKEKSSA SSKLGITMIV SHELAHQWFG NLVTMEWWND 
       370        380        390        400        410        420 
LWLNEGFAKF MEFVSVTVTH PELKVEDYFF GKCFNAMEVD ALNSSHPVST PVENPAQIRE 
       430        440        450        460        470        480 
MFDDVSYEKG ACILNMLRDY LSADTFKRGI VQYLQKYSYK NTKNEDLWNS MMHICPTDGT 
       490        500        510        520        530        540 
QTMDGFCSRS QHSSSTSHWR QEVVDVKTMM NTWTLQKGFP LITITVSGRN VHMKQEHYMK 
       550        560        570        580        590        600 
GSERFPETGY LWHVPLTFIT SKSDSVQRFL LKTKTDVLIL PEAVQWIKFN VGMNGYYIVH 
       610        620        630        640        650        660 
YADDGWASLS GLLKEAHTTI SSNDRASLIN NAFQLVSIEK LSIEKALDLT LYLKNETEIM 
       670        680        690        700        710        720 
PIFQALNELI PMYKLMEKRD MIEVETQFKD FLLKLLKDLI DKQTWTDEGS VSERMLRSQL 
       730        740        750        760        770        780 
LLLACVRNYQ PCVQRAERYF REWKSSNGNM SIPIDVTLAV FAVGAQNTEG WDFLYSKYQS 
       790        800        810        820        830        840 
SLSSTEKSQI EFSLCTSKDP EKLQWLLDQS FKGEIIKTQE FPHILTLIGR NPVGYPLAWK 
       850        860        870        880        890        900 
FLRENWNKLV QKFELGSSSI AHMVMGTTDQ FSTRARLEEV KGFFSSLKEN GSQLRCVQQT 
       910        920        930    
IETIEENIRW MDKNFDKIRL WLQKEKPELL 

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9EQH2-1-unknown MPSLLP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9EQH2-559-unknown ITSKSD... 559 inferred from cleavage unknown TopFIND Inferred from cleavage TC31133

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)