Q9EQR3: Small conductance calcium-activated potassium channel protein 1

General Information

Protein names	- Small conductance calcium-activated potassium channel protein 1 - SK1 - SKCa 1 - SKCa1 - KCa2.1
Gene names	Kcnn1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9EQR3

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Small conductance calcium-activated potassium channel protein 1 - Isoform 3 of Small conductance calcium-activated potassium channel protein 1 - Isoform 4 of Small conductance calcium-activated potassium channel protein 1 - Isoform 5 of Small conductance calcium-activated potassium channel protein 1 - Isoform 6 of Small conductance calcium-activated potassium channel protein 1 - Isoform 7 of Small conductance calcium-activated potassium channel protein 1 - Isoform 8 of Small conductance calcium-activated potassium channel protein 1 - Isoform 9 of Small conductance calcium-activated potassium channel protein 1

Sequence View

        10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG         10         20         30         40         50         60
MSSHSHNGSV GQPLGSGPGF LGWEPVDPEA GRPLQPTQGP GLQMVAKGQP VRLSPGGSRG
        70         80         90        100        110        120
HPQEQEEEEE EEEEEDKTGS GKPPTVSHRL GHRRALFEKR KRLSDYALIF GMFGIVVMVT
       130        140        150        160        170        180
ETELSWGVYT KESLCSFALK CLISLSTVIL LGLVILYHAR EIQLFLVDNG ADDWRIAMTW
       190        200        210        220        230        240
ERVSLISLEL VVCAIHPVPG HYRFTWTARL AFSLVPSAAE ADLDVLLSIP MFLRLYLLAR
       250        260        270        280        290        300
VMLLHSRIFT DASSRSIGAL NRVTFNTRFV TKTLMTICPG TVLLVFSVSS WIVAAWTVRV
       310        320        330        340        350        360
CERYHDKQEV TSNFLGAMWL ISITFLSIGY GDMVPHTYCG KGVCLLTGIM GAGCTALVVA
       370        380        390        400        410        420
VVARKLELTK AEKHVHNFMM DTQLTKRVKN AAANVLRETW LIYKHTRLVK KPDQGRVRKH
       430        440        450        460        470        480
QRKFLQAIHQ AQKLRSVKIE QGKVNDQANT LAELAKAQSI AYEVVSELQA QQEELEARLA
       490        500        510        520        530
ALESRLDVLG ASLQALPGLI AQAICPLPPP WPGPGHLATA THSPQSHWLP TMGSDCG

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9EQR3-1-unknown	MSSHSH...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78788
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78789
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78790
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78791
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78792
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78793
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78794
Q9EQR3-1-unknown	MSSHSH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106858

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GSDCG	537	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GSDCG	537	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74407
...GSDCG	537	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74406
...GSDCG	537	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74412
...GSDCG	537	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74405

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q9EQR3: Small conductance calcium-activated potassium channel protein 1

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates