TopFIND 4.0

Q9ER04: Transmembrane protease serine 5

General Information

Protein names
- Transmembrane protease serine 5
- 3.4.21.-
- Spinesin
Gene names Tmprss5
Organism Mus musculus
Protease Family
Protease ID S01.313
Chromosome location
UniProt ID Q9ER04

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSPTLDDQSP MEIRCTEEGA GPGIFRMELG DQRQSISQSQ RWCCLQRGCV ILGVLGLLAG 
        70         80         90        100        110        120 
AGIASWLLVL YLWPAASPSI SGTLQEEEMT LNCPGVSREE ELLPSLPKTV SFRINGEDLL 
       130        140        150        160        170        180 
LQVQVRARPD WLLVCHEGWS PALGMHICKS LGHIRLTQHK AVNLSDIKLN RSQEFAQLSA 
       190        200        210        220        230        240 
RPGGLVEESW KPSANCPSGR IVSLKCSECG ARPLASRIVG GQAVASGRWP WQASVMLGSR 
       250        260        270        280        290        300 
HTCGASVLAP HWVVTAAHCM YSFRLSRLSS WRVHAGLVSH GAVRQHQGTM VEKIIPHPLY 
       310        320        330        340        350        360 
SAQNHDYDVA LLQLRTPINF SDTVGAVCLP AKEQHFPWGS QCWVSGWGHT DPSHTHSSDT 
       370        380        390        400        410        420 
LQDTMVPLLS TYLCNSSCMY SGALTHRMLC AGYLDGRADA CQGDSGGPLV CPSGDTWHLV 
       430        440        450    
GVVSWGRGCA EPNRPGVYAK VAEFLDWIHD TVQVR

Isoforms

- Isoform 1 of Transmembrane protease serine 5 - Isoform 2 of Transmembrane protease serine 5 - Isoform 3 of Transmembrane protease serine 5

Sequence View

        10         20         30         40         50         60 
MSPTLDDQSP MEIRCTEEGA GPGIFRMELG DQRQSISQSQ RWCCLQRGCV ILGVLGLLAG 
        70         80         90        100        110        120 
AGIASWLLVL YLWPAASPSI SGTLQEEEMT LNCPGVSREE ELLPSLPKTV SFRINGEDLL 
       130        140        150        160        170        180 
LQVQVRARPD WLLVCHEGWS PALGMHICKS LGHIRLTQHK AVNLSDIKLN RSQEFAQLSA 
       190        200        210        220        230        240 
RPGGLVEESW KPSANCPSGR IVSLKCSECG ARPLASRIVG GQAVASGRWP WQASVMLGSR 
       250        260        270        280        290        300 
HTCGASVLAP HWVVTAAHCM YSFRLSRLSS WRVHAGLVSH GAVRQHQGTM VEKIIPHPLY 
       310        320        330        340        350        360 
SAQNHDYDVA LLQLRTPINF SDTVGAVCLP AKEQHFPWGS QCWVSGWGHT DPSHTHSSDT 
       370        380        390        400        410        420 
LQDTMVPLLS TYLCNSSCMY SGALTHRMLC AGYLDGRADA CQGDSGGPLV CPSGDTWHLV 
       430        440        450    
GVVSWGRGCA EPNRPGVYAK VAEFLDWIHD TVQVR         10         20         30         40         50         60 
MSPTLDDQSP MEIRCTEEGA GPGIFRMELG DQRQSISQSQ RWCCLQRGCV ILGVLGLLAG 
        70         80         90        100        110        120 
AGIASWLLVL YLWPAASPSI SGTLQEEEMT LNCPGVSREE ELLPSLPKTV SFRINGEDLL 
       130        140        150        160        170        180 
LQVQVRARPD WLLVCHEGWS PALGMHICKS LGHIRLTQHK AVNLSDIKLN RSQEFAQLSA 
       190        200        210        220        230        240 
RPGGLVEESW KPSANCPSGR IVSLKCSECG ARPLASRIVG GQAVASGRWP WQASVMLGSR 
       250        260        270        280        290        300 
HTCGASVLAP HWVVTAAHCM YSFRLSRLSS WRVHAGLVSH GAVRQHQGTM VEKIIPHPLY 
       310        320        330        340        350        360 
SAQNHDYDVA LLQLRTPINF SDTVGAVCLP AKEQHFPWGS QCWVSGWGHT DPSHTHSSDT 
       370        380        390        400        410        420 
LQDTMVPLLS TYLCNSSCMY SGALTHRMLC AGYLDGRADA CQGDSGGPLV CPSGDTWHLV 
       430        440        450    
GVVSWGRGCA EPNRPGVYAK VAEFLDWIHD TVQVR         10         20         30         40         50         60 
MSPTLDDQSP MEIRCTEEGA GPGIFRMELG DQRQSISQSQ RWCCLQRGCV ILGVLGLLAG 
        70         80         90        100        110        120 
AGIASWLLVL YLWPAASPSI SGTLQEEEMT LNCPGVSREE ELLPSLPKTV SFRINGEDLL 
       130        140        150        160        170        180 
LQVQVRARPD WLLVCHEGWS PALGMHICKS LGHIRLTQHK AVNLSDIKLN RSQEFAQLSA 
       190        200        210        220        230        240 
RPGGLVEESW KPSANCPSGR IVSLKCSECG ARPLASRIVG GQAVASGRWP WQASVMLGSR 
       250        260        270        280        290        300 
HTCGASVLAP HWVVTAAHCM YSFRLSRLSS WRVHAGLVSH GAVRQHQGTM VEKIIPHPLY 
       310        320        330        340        350        360 
SAQNHDYDVA LLQLRTPINF SDTVGAVCLP AKEQHFPWGS QCWVSGWGHT DPSHTHSSDT 
       370        380        390        400        410        420 
LQDTMVPLLS TYLCNSSCMY SGALTHRMLC AGYLDGRADA CQGDSGGPLV CPSGDTWHLV 
       430        440        450    
GVVSWGRGCA EPNRPGVYAK VAEFLDWIHD TVQVR



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9ER04-1-unknown MSPTLD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9ER04-11-unknown MEIRCT... 11 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92550
    Q9ER04-145-unknown MHICKS... 145 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92549
    Q9ER04-145-unknown MHICKS... 145 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103463

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)