TopFIND 4.0

Q9ERA7: Mesothelin

General Information

Protein names
- Mesothelin
- Pre-pro-megakaryocyte-potentiating factor
- Protein expressed in renal carcinoma
- Megakaryocyte-potentiating factor
- MPF
- Mesothelin, cleaved form
Gene names Msln
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9ERA7

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALPTAQPLL GSCGSPICSR SFLLLLLSLG WLPLLQTQTT RTSQEAALLH AVTGTVDFAS 
        70         80         90        100        110        120 
LPTGLFLGLM CDEVSGLSMG HAKELAMAVR QKNIVLQVHQ LRCLARRLPK HLTNEELDAL 
       130        140        150        160        170        180 
PLDLLLFLNP AMFPGQQACA HFFSLISKAN VNVLPRRSLE RQRLLTGALK CQGVYGFQVS 
       190        200        210        220        230        240 
ETDARALGGL ACDLPGEFVA KSSEVLLPWL ARCGGPLDQG QAKAVREVLR SGRAPYGPPS 
       250        260        270        280        290        300 
TWSVSTLDAL QGLLVVLDES IVHSIPKDVI TEWLQGISRE PSRLGSKWTV THPRFRRDTE 
       310        320        330        340        350        360 
QKACPPGKEP NVVDENLIFY QNWELEACVD GTLLAGQMDL VNEIPFTYEQ LSIFKHKLDK 
       370        380        390        400        410        420 
TYPQGYPESL IKQLGHFFRY VSPEDIRQWN VTSPDTVNTL LKVSKGQKMD AQVIALVACY 
       430        440        450        460        470        480 
LRGGGKLDED IVKALDNIPL SYLCDFSPQD LHAIPSSVMW LVGLHDLDKC SQRHLGILYQ 
       490        500        510        520        530        540 
KACSAFQNVS GLEYFEKIRT FLGGASREDL RALSQHNVSM DIATFKKLQV DALVGLSVAE 
       550        560        570        580        590        600 
VQKLLGPHIG DLKTEEDKSP VRDWLFRQQQ KDLDSLGLGL QGGIPNGYLI LDFNVREAFS 
       610        620    
SGAPLLGPGF VFAWIPALLS ALRLS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9ERA7-36-unknown QTQTTR... 36 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9ERA7-298-unknown DTEQKA... 298 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LGSKWT 288 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...REAFSS 600 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)